Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: CAZymes from Terrestrial and Aquatic Ecosystems
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:20 pm
"Mining Microbiomes for Nature's CAZymes"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:05 pm
"Functional Exploration of the CAZy Databank and Beyond: Discovery of New Families and Substrate Specificities"
9:05 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Plant Cell Walls and Implications to Their Bioconversion
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"The Importance of Precise Substitution Patterns for Interactions of Hemicelluloses with Cellulose Fibrils"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Sugars from the Sea: Cell Wall Polysaccharides from Macroalgae"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Functional Analysis of Polygalacturonases During Water-Conducting Cell Formation Required for Plant Adaptation to Land"
11:15 am - 11:25 am
Discussion
11:25 am - 11:50 am
"The Remarkable Wall-Loosening Actions of a Maize β-Expansin"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
"Visualizing Polysaccharide Uptake Using Fluorescent Glycan Conjugates and Single Cell Microscopy"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Enzyme Action on Intermolecular Linkages and Complex Carbohydrate Structures
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Elucidating the Action of Glucuronoyl Esterases: From Model Substrates to Action on Lignin Carbohydrate Complexes"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Systems Biology Approaches to Characterize Bacterial Chitinases: A Microbe-Centric Perspective on the Degradation of Complex Insoluble Substrates"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:10 pm
"Divide and Conquer: Using Subfamily Analysis to Refine Specificity Determination and Prediction in GH16"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Carbohydrate Active Enzyme Cascades from Diverse Habitats
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Solving the Puzzle of Anaerobic Biomass Degradation: Metatranscriptomics of Rumen Fungi"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Where the Wild Things Are: CAZyme Lessons Learnt from Wild and Domestic Herbivores"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:05 am
"The Critical Roles of Sulfatases and Fucosidases in Mucin Utilization by Bacteroides"
11:05 am - 11:10 am
Discussion
11:10 am - 11:35 am
"Expanding the Notion of Polysaccharide Utilization Loci: Carrageenan Catabolism in Marine Heterotrophic Bacteria"
11:35 am - 11:45 am
Discussion
11:45 am - 12:10 pm
"Exploring the Marine Glyco-Carbon Cycle with CAZymes"
12:10 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Multi-Enzyme Complexes in Nature and by Design
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Ancestral Enzymes: Towards Highly Efficient Biomass Conversion"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Seaweedosome: Engineering of an Efficient Agarose-Degrading Multi-Enzyme Complex"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"VersaTile: A High-Throughput DNA Assembly Method for the Combinatorial Construction and Evaluation of Cellulosome Components"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Oxidative Enzymes and Their Partners
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Connecting the Dots Between Oxidoreductases in Lignocellulose Conversion"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Discovery of Fungal Copper Proteins Evolutionarily Related to Lytic Polysaccharide Monooxygenases"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
"Activation of a Bacterial Lytic Polysaccharide Monooxygenase Using a Small C-Type Cytochrome"
11:10 am - 11:15 am
Discussion
11:15 am - 11:40 am
"Biophysical Studies of Cellulose Oxidation: Effects on Water and Enzyme Interactions with Cellulose Surfaces"
11:40 am - 11:50 am
Discussion
11:50 am - 12:15 pm
"Lytic Polysaccharide Monooxygenases in Preparation of Cellulosic Materials"
12:15 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Carbohydrate-Active Enzymes for New Bio-Based Chemicals and Materials
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Engineering of Glycosidases for Enzymatic Synthesis of Human Milk Oligosaccharides"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"New Cellulosic Materials via Cellulose Endo-Transglycosylases and Cellodextrin Phosphorylases"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"Interplay Between Cellulose Defects, Nanomechanics and Cellulases: New Insights and Implications for Production of Nanocellulose"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Emerging Tools for CAZyme Discovery, Design and Development
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Production Hosts for the Characterization of New Carbohydrate-Active Enzymes"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Unbiased Simulations of CAZy Reaction Mechanisms for Enzyme Engineering"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Redesigning N-Glycosylation Sites to Improve CAZyme Efficiency"
11:15 am - 11:25 am
Discussion
11:25 am - 11:50 am
"Machine Learning in Enzyme and Biomaterial Design"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Selected Poster Presentations
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"The Effect of LPMOs and Endoglucanases on Cellulose Accessibility and Productive Enzyme Binding"
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Roseburia intestinalis : A Primary Degrader of Dietary β-Mannans"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Breakdown and Utilization of Arabinogalactan by Bacteroides in the Human Gut"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:05 pm
"The Role of TonB in Polysaccharide Utilization by the Bacteroidetes"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:20 pm
"Increasing the Digestibilty of Non-Starch Dietary Polysaccharides with CAZymes Bioprospected from the Chicken Intestinal Microbiome"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure