Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Chemical, Biological, and Systems-Based Methods for the Study of Glycosylation
Discussion Leader: Alyssa Pirinelli (University of Minnesota Morris, USA)
3:45 pm - 4:20 pm
Lara Mahal (New York University, USA)
"Cracking the Glycocode"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Uncovering the Role of Carbohydrates in Immunology
Discussion Leaders: Christian Toonstra (Johns Hopkins University, USA) and Klare Lazor (University of Delaware, USA)
7:30 pm - 7:50 pm
Helene Pfister (National Institutes of Health, USA)
"Neutralization of Neuropathy-Inducing Anti-MAG Antibodies by Multivalent Glycoconjugates"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Raiees Andrabi (The Scripps Research Institute, USA)
"Glycans as Anchors for Inducing HIV Broadly Neutralizing Antibodies"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Kelly Craft (Vanderbilt University, USA)
"Human Milk Oligosaccharides and Their Effect on Group B Streptococcus"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Wei Qin (Peking University, China)
"O-GlcNAc Regulates Box C/D snoRNP Biogenesis by Stablizing the Core Components"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Jason Labonte (Johns Hopkins University, USA)
"RosettaCarbohydrate: A Framework for Residue-Centric Modeling and Design of Saccharide and Glycoconjugate Structures"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Katelyn Erickson (University of North Carolina at Charlotte, USA)
"Development and Analysis of a Novel Targeting Strategy for Bacterial Sugars"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Complex Carbohydrates: Using Chemistry to Answer Critical Biological Questions
Discussion Leaders: Matthew Zhou (Stanford University, USA) and Teodora Kljaic (University of Maryland, USA)
9:00 am - 9:20 am
Benjamin Schumann (Stanford University, USA)
"Glycosyltransferase Bump-Hole Engineering to Dissect Mucin-Type O-Glycosylation in Living Cells"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Shonoi Ming (U.S. Food and Drug Administration, USA)
"Mechanism of Action of Neisseria Meningitis C Polysialyltransferase"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
Regis Saliba (Indiana University, USA)
"Challenges in the Automated Solution Phase Syntheses of Potential Immunological Oligosaccharide Adjuvants"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Eric Sletten (University of Iowa, USA)
"Neo-Glycopolymer Heparan Sulfate Polysaccharide Mimics as Potent Tight-Binding Inhibitors of Heparanase"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Shifra Lansky (The Hebrew University of Jerusalem, Israel)
"Multiple Conformational States of a Unique Extracellular Arabinanase Suggest a 'Harpoon' Mechanism of Action"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Jenna DeSousa (Vanderbilt University, USA)
"Studies Towards the Total Synthesis of Arimetamycin A and Its Biological Disaccharide"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Panel
Discussion Leaders: Victoria Kohout (Indiana University, USA) and Ross Mancini (University of Toronto, Canada)
1:30 pm - 2:30 pm
Panel Discussion
Careers in Academic, Government, and Primarily Undergraduate Institutions
Nicole Snyder Lee (Davidson College, USA)
Steven Townsend (Vanderbilt University, USA)
Willie Vann (U.S. Food and Drug Administration, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
