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Carbohydrates (GRS)

Gordon Research Seminar

Approaches in Carbohydrate Synthesis and Tools to Investigate Glycan Functions

June 17 - 18, 2023
Chairs and
Holderness School
33 Chapel Lane
Holderness, New Hampshire, United States
 Venue and Travel Information

Conference Description

The Carbohydrates GRS provides a unique forum for young doctoral and post-doctoral researchers to present their work, discuss new methods, cutting edge ideas, and pre-published data, as well as to build collaborative relationships with their peers. Experienced mentors and trainee moderators will facilitate active participation in scientific discussion to allow all attendees to be engaged participants rather than spectators.

Carbohydrates are implicated in a wide range of biological functions and disease. Challenges in the development of carbohydrate tools and potential therapeutics are often attributed to the complexities of structure and function relationships. The 2023 Gordon Research Seminar (GRS) on Carbohydrates will encompass multi-disciplinary research from topics on synthesis to biological applications. Through oral presentations, poster presentations, and discussions, we will advance our understanding and generate ideas to drive innovation in synthesis, biological applications and therapeutic uses of carbohydrates.

Due to limited accommodations at this venue, guest housing is very limited. To request family/guest housing please reach out to your Conference Operations Associate.

Related Meeting

This GRS will be held in conjunction with the "Carbohydrates" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: From Stereocontrolled Glycosylation to Automated Chemical Synthesis of Glycans
Discussion Leader:
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:20 pm
"From Stereocontrolled Glycosylation to Automated Chemical Synthesis of Glycans"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Recent Methodologies in Carbohydrate Synthesis
Discussion Leader:
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:45 pm
"Synthesis of Streptococcus Pneumoniae 6A/6C Capsulare Polysaccharide Fragments"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
"Construction of a 4-N-Acetyl Sialoside Library to Explore Biological Functions of 4-O-Acetyl Sialic Acid"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Expanding the Scope of Stereoselective A-Galactosylation Using Glycosyl Halides"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
"Rational Design and Expedient Synthesis of Heparan Sulfate-Like Oligosaccharides from Natural Aminoglycosides for Structure and Activity Relationship Studies"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:05 pm
"Synthesis of a Novel Hyaluronic Acid Mimetic via an Anionic Ring Opening Polymerization"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Advancing Academic Glyco Ideas for Commercial Purposes"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Tools for Glycan Analysis and Biological Function in Vitro and in Vivo
Discussion Leader:
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:20 am
"Production of a Glycan Microarray to Rapidly Investigate Carbohydrate-Protein Interactions"
9:20 am - 9:25 am
Discussion
9:25 am - 9:40 am
"A Sweet Treat: Employment of Human Milk Oligosaccharides as Adjuvants in the Antimicrobial Arms Race"
9:40 am - 9:45 am
Discussion
9:45 am - 10:00 am
"Fine Glycan Specificity of Immune Lectins: A Comprehensive Mass Spectrometry Study"
10:00 am - 10:05 am
Discussion
10:05 am - 10:20 am
"GMMA as an Alternative Carrier for a Glycoconjugate Vaccine against Group A Streptococcus"
10:20 am - 10:25 am
Discussion
10:25 am - 10:40 am
"The Role of Sialidase for Coronavirus Infection"
10:40 am - 10:45 am
Discussion
10:45 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Navigating a Career in Carbohydrate Chemistry and Glycobiology
Discussion Leader:
1:30 pm - 1:50 pm
Introduction by Discussion Leader
1:50 pm - 2:30 pm
Panel Discussion
Careers in Carbohydrate Chemistry and Glycobiology
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes

Contributors

National Institutes of Health (NIH)
New England BioLabs, Inc.
Omicron Biochemicals, Inc.
Glycan Therapeutics

Research reported in this publication was supported by the National Institute Of Allergy And Infectious Diseases of the National Institutes of Health under Award Number R13AI161936. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Conference Links

Conference History Carbohydrates
Additional Fee Info

Carbohydrates
June 15 - 20, 2025


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