SUNDAY |
4:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 8:30 pm | Sudden Cardiac Death: Where are we and where are we going in the next 20 years? |
7:30 pm - 7:45 pm | Conference Introduction: José Jalife (SUNY Upstate Medical University) |
7:45 pm - 8:30 pm | Douglas P. Zipes (Indiana University) Sudden Cardiac Death: Where are we and where are we going in the next 20 years? |
8:30 pm - 9:30 pm | Panel Discussion |
| Major challenges and opportunities related to the mechanisms of arrhythmias and sudden cardiac death |
| Discussion Leader: Douglas P. Zipes (Indiana University) |
| David Lathrop (National Institutes of Health) |
| Roger Karam (Procter & Gamble Pharmaceuticals) |
| Walter Olson (Medtronic, Inc) |
| Mark Kroll (St. Jude, Inc) |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Photo |
9:00 am - 12:30 pm | Sodium Channel Dysfunction as a Trigger of Arrhythmias |
| Discussion Leader: Augustus Grant (Duke University) |
9:00 am - 10:00 am | Robert Kass (Columbia University) Mutations in cardiac sodium channels: clinical implications |
10:00 am | Coffee Break |
10:30 am - 11:30 am | Jonathan Makielski (University of Wisconsin - Madison)
Trafficking defects and rescue of Na channel arrhythmia mutations |
11:30 am - 12:30 pm | Yoram Rudy (Washington University) Modeling the electrophysiological consequences of sodium channel dysfunction |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Potassium Channels and Reentrant Mechanisms |
| Discussion Leader: Gideon Koren (Harvard University) |
7:30 pm - 8:10 pm | Jeanne Nerbonne (Washington University) Voltage-regulated channels and arrhythmias |
8:10 pm - 8:50 pm | Louis J. Ptacek (University of Utah) Genetics of Kir2.x channels and arrhythmias |
8:50 pm - 9:30 pm | Anatoli Lopatin (University of Michigan) Inward rectifying channels in mouse models of fibrillation |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Intracellular Calcium Cycling and Arrhythmias |
| Discussion Leader: Donald Bers (Loyola University) |
9:00 am - 10:00 am | David Yue (Johns Hopkins)
Calmodulin regulation of L-type (CaV1) Ca2+ channels: impact on ventricular excitability and beyond |
10:00 am | Coffee Break |
10:30 am - 11:30 am | Steven Pogwizd (University of Illinois) Na/Ca exchange, contractile dysfunction and arrhythmogenesis |
11:30 am - 12:30 pm | Guy Salama (University of Pittsburgh) Intracellular Calcium as a trigger of Arrhythmias |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Cell-to-Cell Communication in Health and in Disease |
| Discussion Leader: Denis Escande(Universite De Nantes, France) |
7:30 pm - 8:10 pm | Mario Delmar (SUNY Syracuse) Regulation of connexin function by their binding partners |
8:10 pm - 8:50 pm | Jeffrey Saffitz (Washington University) Gap junctions and cell junctions in health and disease |
8:50 pm - 9:30 pm | Stephan Rohr (University of Berne) Coupling of cardiac myocytes by fibroblasts of cardiac origin |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Reentry and Ventricular Fibrillation |
| Discussion Leader: Igor Efimov (Washington University) |
9:00 am - 10:00 am | Peter Backx (University of Toronto)
Regulation of K+ channels and heterogeneity of repolarization in the heart |
10:00 am | Coffee Break |
10:30 am - 11:30 am | Alexey Zaitsev (SUNY Syracuse) Many Faces of Ventricular Fibrillation in an Ischemic Heart |
11:30 am - 12:30 pm | Alain Karma (Northeastern University) Nonlinear dynamics of fibrillation |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Mechanisms of Atrial Fibrillation from Bench to Bedside |
| Discussion Leader: David Van Wagoner (Cleveland Clinic) |
7:30 pm - 8:10 pm | Ursula Ravens (Technical University Dresden, Germany) Ion channel remodeling and atrial fibrillation |
8:10 pm - 8:50 pm | Stanley Nattel (Montreal Heart Institute) Mechanisms of atrial fibrillation in animal models |
8:50 pm - 9:30 pm | Andrea Natale (Cleveland Clinic) Mechanisms of atrial fibrillation in man |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Genetics and Arrhythmogenesis |
| Discussion Leader: Michael Sanguinetti (University of Utah) |
9:00 am - 10:00 am | Ira Cohen (SUNY at StonyBrook) Genes, Stem Cells, Funny Currents and Biological Pacemakers |
10:00 am | Coffee Break |
10:30 am - 11:30 am | Barry London (University of Pittsburgh) Molecular genetics of Channelopathies |
11:30 am - 12:30 pm | Wojciech Zareba (University of Rochester) Risk stratification of channelopathies |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Stem Cells and the future of Cardiac Arrhythmias |
| Discussion Leader: André Kléber (University of Berne) |
7:30 pm - 8:10 pm | Leo Gepstein (Technion, Haifa Israel) Somatic gene and cell therapy strategies for the treatment of cardiac arrhythmias |
8:10 pm - 8:50 pm | Ronald Li (Johns Hopkins)
Electrophysiological properties of pluripotent human and mouse embryonic stem cells |
8:50 pm - 9:30 pm | Timothy Kamp (University of Wisconsin - Madison) Diversity of cardiomyocytes derived from human embryonic stem cells |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |