Saturday |
1:30 pm - 4:30 pm | Arrival and Check-in |
3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:15 pm - 4:00 pm | Engineered Tissue: What's New? |
| Discussion Leader: Eva Rog-Zielinska (Imperial College London, NHLI, United Kingdom) |
3:15 pm - 3:25 pm | Adriana Blazeski (Johns Hopkins University School of Medicine, USA) "Functional Studies of Human Pluripotent Stem Cell-Derived Cardiomyocytes on Engineered Heart Slices" |
3:25 pm - 3:30 pm | Discussion |
3:30 pm - 3:40 pm | Haruyo Yasui (Osaka University Graduate School of Medicine, Japan) "Electrical Properties of Three-Dimensional Engineered Hearts Using Decellularized Extracellular Matrix" |
3:40 pm - 3:45 pm | Discussion |
3:45 pm - 4:00 pm | General Discussion |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | Ion Channels and Arrhythmias |
| Discussion Leader: Francis Ortega (Weill Cornell Medical College, USA) |
5:30 pm - 6:00 pm | Keynote: Jose Jalife (University of Michigan, USA) "What is Hot, Up and Coming in Cardiac Arrhythmia Research Now and in the Next Ten Years" |
6:00 pm - 6:15 pm | Discussion |
6:15 pm - 6:25 pm | Mathilde Rivaud (New York University Medical Center, USA) "Location-Specific Remodeling of Distinct Sodium Channel Pools in the Murine Failing Heart" |
6:25 pm - 6:30 pm | Discussion |
6:30 pm - 6:40 pm | Rosy Joshi-Mukherjee (Johns Hopkins University School of Medicine, USA) "Loss of Calmodulin-Mediated Regulation of Na+ Channel Causes Remodeling of Electrical and Junctional Proteins; and Induces Dilated Cardiomyopathy in IQ/AA+/- Mice" |
6:40 pm - 6:45 pm | Discussion |
6:45 pm - 6:55 pm | Przemyslaw Radwanski (The Ohio State University, USA) "A Novel Role for Nav1.6 in Arrhythmogenic Diastolic Ca2+ Release: Neuronal Na+ Channels and the Microdomain Na+/ Ca2+" |
6:55 pm - 7:00 pm | Discussion |
7:00 pm - 7:10 pm | Jerome Clatot (Case Western Reserve University, USA) "Interaction of the Cardiac Sodium Channel α-Subunits Leads to Coupled Gating Properties" |
7:10 pm - 7:15 pm | Discussion |
7:15 pm - 7:25 pm | Nicoline Smit (Academic Medical Center, The Netherlands) "Human Adipose Tissue-Derived Stromal Cells Exert Pro-Arrhythmic Effects Through Direct Interaction in Monolayers of Cardiomyocytes" |
7:25 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
Sunday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Integrated Approaches to Translational Science |
| Discussion Leader: Elisa Passini (University of Bologna, Italy) |
9:00 am - 9:10 am | Bastiaan Boukens (Washington University at St. Louis, USA) "Slow and Discontinuous Conduction Underlie Fractionation in the Human RVOT" |
9:10 am - 9:15 am | Discussion |
9:15 am - 9:25 am | Gary Mirams (University of Oxford, United Kingdom) "Mathematical Electrophysiology Modelling in Cardiac Safety Testing" |
9:25 am - 9:30 am | Discussion |
9:30 am - 9:40 am | Farhad Pashakhanloo (Johns Hopkins University, USA) "Novel High-Resolution Image-Based Model of Whole Human Atria with Realistic Subject-Specific Fiber Orientation" |
9:40 am - 9:45 am | Discussion |
9:45 am - 9:55 am | Jheel Patel (Krannert Institute of Cardiology, USA) "Stellate Ganglion Damage Induced by Vagal Nerve Stimulation and Renal Sympathetic Nerve Ablation" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Panel Discussion |
| "Obtaining Funding and Starting Your Own Lab" |
|
- Peter Kohl (Imperial College London, United Kingdom)
- Alex Quinn (Dalhousie University, Canada)
|
10:30 am - 11:00 am | Panel Discussion |
| "Career Paths After PhD/Post-Doc" |
|
- Jose Jalife (University of Michigan, USA)
- Mark Marshall (Medtronic, USA)
- Gail Robertson (University of Wisconsin, Madison, USA)
|
11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Novel Perspectives on Intercellular Transduction |
| Discussion Leader: David Jones (University of Wisconsin-Madison, USA) |
1:30 pm - 1:40 pm | Colin Peters (Simon Fraser University, Canada) "Proton Dependency of Ionic and Gating Currents in the E1784K Brugada Syndrome Mutant" |
1:40 pm - 1:45 pm | Discussion |
1:45 pm - 1:55 pm | Katherine Holzem (Washington University at St. Louis, USA) "3-Dimensional Molecular Phenotyping of the Human Cardiac Conduction System Using CLARITY" |
1:55 pm - 2:00 pm | Discussion |
2:00 pm - 2:10 pm | Emily Ongstad (Clemson University / Virginia Tech Carillon Research Institute, USA) "A Cx43 CT-Mimetic Peptide Alters Cx43 and Cx43pS368 Heterocellular Interactions in the Injury Border Zone" |
2:10 pm - 2:15 pm | Discussion |
2:15 pm - 2:25 pm | Anastasia Vasilyeva (Ural Federal University, Russia) "Increase in Heterogeneity Between Subepi- and Subendocardial Myocytes Under Acute Ischemia May Facilitate Rhythm Disturbances in the Myocardium" |
2:25 pm - 2:30 pm | Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |