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Cardiac Regulatory Mechanisms

Gordon Research Conference

July 19 - 24, 1998
Chair Eduardo Marban
Vice Chair Donald M. Bers
Colby-Sawyer College
541 Main Street
New London, New Hampshire, United States
 Venue and Travel Information

Conference Description

This conference will bring together experts from around the world to focus on new developments in cardiac excitability and excitation-contraction coupling. Links to human disease, particularly arrhythmias and heart failure, will be emphasized wherever possible. Consistent with the general philosophy of the Gordon Research Conferences, the speakers will present novel, unpublished results with vigorous discussion to follow. Late-breaking developments and younger scientists will participate as presenters of thematically-organized posters. Each platform session will also include one 10 min talk selected by competition among such participants.

International Advisory Committee: Paul D. Allen (Harvard); Yoshi Kurachi (Osaka U., Japan); Ursula Ravens (Dresden, Germany); Guy Vassort (Montpellier, France); Andy Wasserstrom (Northwestern Univ.)

Conference Program

Receptors/signal transduction - July 19 PM
Discussion leader: Susan Steinberg (Columbia Univ.)
  • Ed Lakatta (NIA, NIH): New developments in ß-adrenergic signalling
  • Marlene Hosey (Northwestern Univ.): G protein-coupled receptors
  • Brian Kobilka (Stanford Univ.): Molecular analysis of adrenergic receptors
Ion channels I - July 20 AM
Discussion leader: Akinori Noma (Kyoto Univ.)
  • Claire Townsend (Thomas Jefferson Univ): Sodium channels
  • David Yue (Johns Hopkins Univ.): Calcium channels
  • Edward Perez-Reyes (Loyola Univ.): Molecular structure of T-type channels
  • Cruickshank Lecturer: Lily Jan (UCSF): Inward rectifier channels
Ion channels II - July 20 PM
Discussion leader: Jeanne Nerbonne (Wash. U.)
  • Rodolphe Fischmeister (Orsay, France): Local control of cardiac Ca2+ channel regulation"
  • Yoshi Kurachi (Osaka, Japan): Heterogeneity of KATP channels
  • Michel Lazdunski (Valbonne, France): Novel cardiac potassium channels
Control of cardiac excitability and contractility by energy metabolism - July 21 AM
Discussion leader: Guy Vassort (Montpellier, France)
  • Brian O’Rourke (Johns Hopkins Univ.): Primary oscillations of energy metabolism
  • Robert Balaban (NIH): Control of cardiac energy metabolism
  • James N. Weiss (UCLA): Effects of metabolic inhibition on E-C coupling
  • Colin Nichols (Wash. U.): ATP-dependent potassium channels
Cell-cell communication - July 21 PM
Discussion leader: Jose Jalife (Syracuse, NY)
  • Eric Beyer (Washington U.): Molecular biology of gap junctions
  • Stephan Rohr (Bern, Switzerland): Insights into arrhythmias from patterned cell growth
  • Yoram Rudy (Case Western Reserve): Quantitative models of excitation and propagation
Calcium cycling proteins - July 22 AM
Discussion leader: Cecilia Mundiña-Weilenmann (La Plata, Argentina)
  • Ken Philipson (UCLA): Sodium-calcium exchange
  • Michitoshi Tada (Osaka, Japan): Interactions between phospholamban and SERCA
  • Michael Fill (Loyola Univ.): Cardiac ryanodine receptors
  • Jon Lederer (U. of Maryland): Local control of calcium release
Excitation-contraction coupling - July 22 PM
Discussion leader: Martin Morad (Georgetown)
  • Don Bers (Loyola): Inward and outward calcium flux pathways
  • Gil Wier (U. of Maryland): Sparks and subsparks
  • Peter Lipp (Cambridge, England): Subcellular calcium release mechanisms
Links between calcium and force generation - July 23 AM
Discussion leader: Masao Endoh (Yamagata Univ., Japan)
  • Greg Ferrier (Dalhousie, Nova Scotia): Voltage-dependent calcium release
  • Larry Jones (Krannert Institute): Triadin, junctin et al.
  • John Solaro (U. of Illinois): New insights into myofilament structure-function relationships
  • Neal Epstein (NIH): Molecular bases of heritable cardiomyopathies
After-dinner speaker - July 23 PM
  • Mark Keating (U. of Utah): Molecular genetics of cardiovascular disease

Contributors

American Heart Association, Basic Science Council
Bristol Myers Squibb
Cardiac Muscle Society
Eli Lilly Co.
Gordon Research Conferences
Hoffmann/LaRoche Pharmaceuticals
Japan Heart Foundation
Medtronic Inc.
Merck Laboratories
Procter & Gamble Pharmaceuticals

Conference Links

Conference History
Additional Fee Info

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