SATURDAY |
1:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | New Concepts / Emerging Themes in Cardiovascular Biology |
| Discussion Leader: Andrew Edwards (Oslo University Hospital, Norway) |
3:45 pm - 3:57 pm | Pearl Quijada (San Diego State University Heart Institute)
"Enhancing Myocardial Repair with CardioChimeras" |
3:57 pm - 4:00 pm | Discussion |
4:00 pm - 4:12 pm | Ronald Vagnozzi (Cincinnati Children's Hospital)
"Revealing the Contribution of Endogenous c-Kit+, Sca-1+, and ABCG2+ Cells to Post-Myocardial Infarction Cardiac Regeneration Using Genetic Lineage Tracing" |
4:12 pm - 4:15 pm | Discussion |
4:15 pm - 4:27 pm | Emma Monte (University of California, Los Angeles)
"HMGB2 Regulates Chromatin Organization, Counteracting Hypertrophic Remodeling" |
4:27 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Frontiers in Calcium Handling and Cardiac Hypertrophy |
| Discussion Leaders: Kimberley Mellor (University of Auckland, New Zealand) and Anuradha Kalyanasundaram (Ohio State University) |
7:30 pm - 7:44 pm | Robert N. Correll (Cincinnati Children's Hospital)
"Enhanced Cardiac Expression of STIM1 Results in Hypertrophy and RyR2 Dysfunction" |
7:44 pm - 7:50 pm | Discussion |
7:50 pm - 8:04 pm | Joe Zhang (University of Otago, New Zealand)
"The Role of Histidine-Rich Ca2+ Binding Protein (HRC) in Regulation of Store Overload Induced Ca2+ release (SOICR)" |
8:04 pm - 8:10 pm | Discussion |
8:10 pm - 8:24 pm | Girish Melkani (San Diego State University Heart Institute)
"Laminopathy Induced Cardiomopathy Reveals Cytoplasmic Aggregates and Altered Redox Homeostasis" |
8:24 pm - 8:30 pm | Discussion |
8:30 pm - 8:44 pm | Michael Frisk (University of Olso, Norway)
"In Vivo Strain Measurements Predict Regional Disruption of Cardiomyocyte Structure and Ca2+ Homeostasis During Heart Failure" |
8:44 pm - 8:50 pm | Discussion |
8:50 pm - 9:04 pm | Michael Makara (Ohio State University Wexner Medical Center)
"Ankyrin-G Coordinates Intercalated Disc Signaling Platform to Regulate Cardiac Excitability In Vivo" |
9:04 pm - 9:10 pm | Discussion |
9:10 pm - 9:24 pm | Christopher Traynham (Temple University)
"Elucidating the Role of GRK5 in Physiological Hypertrophy" |
9:24 pm - 9:30 pm | Discussion |
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | New Insights into Cardiac Injury and Regeneration |
| Discussion Leaders: Agnese Petrera (University of Freiburg, Germany) and Jennifer Schwanekamp (Cincinnati Children's Hospital) |
9:00 am - 9:14 am | Carlos A. Valverde (Centro de Investigaciones Cardiovascular, La Plata, Argentina)
"Ca2+ Sparks and Ca2+ Waves Are the Subcellular Events Underlying Ca2+ Overload During Ischemia and Reperfusion in Perfused Intact Hearts" |
9:14 am - 9:20 am | Discussion |
9:20 am - 9:34 am | Jennifer Kwong (Cincinnati Children's Hospital)
"Mitochondrial Phosphate Depletion as a Novel Model of Cardiac Energy Starvation" |
9:34 am - 9:40 am | Discussion |
9:40 am - 9:54 am | Moshi Song (Washington University School of Medicine)
"Mitochondrial Fission and Fusion Coordinate Biogenesis and Reciprocally Orchestrate Mitophagic Culling in Mouse Hearts" |
9:54 am - 10:00 am | Discussion |
10:00 am - 10:14 am | Charles Gray (University of California, San Diego)
"CaMKIId Splice Variants Exert Differential Effects on Ischemia / Reperfusion Injury and NF-κB Signaling" |
10:14 am - 10:20 am | Discussion |
10:20 am - 10:34 am | Varun Nagpal (Northwestern University)
"Specific MiRNAs Are Critical for Fibroblast-to-Myofibroblast Transition and Cardiac Fibrosis In Vivo" |
10:34 am - 10:40 am | Discussion |
10:40 am - 10:55 am | Catherine Makarewich (Temple University School of Medicine)
"Transient Receptor Potential Channels Contribute to Pathological Structural and Functional Remodeling After Myocardial Infarction" |
10:55 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:45 pm | Training Tomorrow's Cardiovascular Researchers: Perspectives from Pioneers |
| How Scientific Breakthroughs Actually Happen and the Personal Qualities that Most Contribute to Exceptional Careers |
| Discussion Leaders: Jerry Curran (Ohio State University) and Mirko Völkers (University Hospital Heidelberg, Germany) |
1:30 pm - 1:50 pm | Jeffrey Robbins (Cincinnati Children's Hospital)
"Transformative Science in an Uncertain Era" |
1:50 pm - 1:55 pm | Discussion |
1:55 pm - 2:15 pm | Thomas Eschenhagen (University Medical Center of Hamburg-Eppendorf, Germany)
"Engineering Cardiac Tissues - Take an Opportunity and Keep on Going" |
2:15 pm - 2:20 pm | Discussion |
2:20 pm - 2:40 pm | Gerald W. Dorn II (Washington University School of Medicine)
"Doing Biomedical Research in a Quantum Universe" |
2:40 pm - 2:45 pm | Discussion |
2:45 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |