SUNDAY |
4:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:45 pm | Welcome / Introductory Comments by GRC Site Staff |
7:45 pm - 9:00 pm | A 3-DIMENSIONSIONAL BASIS FOR CHEMISTRY AND BIOCHEMISTRY |
7:45 pm - 8:00 pm | Chair: George Truscott (Keele University, UK) |
8:00 pm - 8:30 pm | Madeleine Helliwell (University of Manchester, UK)
"The chemical basis of the bathochromic shift in the lobster carapace; crystal structures of unbound carotenoids" |
8:30 pm - 9:00 pm | Hansgeorg Ernst (BASF, Germany)
"The remarkable dual-functional antioxidant properties of the bacterial carotenoid dihydroxisorenieratene and its affinity for DPPC membranes I: Synthesis" |
| Hans-Dieter Martin (University of Duesseldorf, Germany)
"The remarkable dual-functional antioxidant properties of the bacterial carotenoid dihydroxisorenieratene and its affinity for DPPC membranes II: Properties" |
9:00 pm - 9:20 pm | Discussion |
9:20 pm | Mixer |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | CAROTENOID ANALYSIS, CHEMISTRY AND PROPERTIES |
9:00 am - 9:15 am | Chair: Synnøve Liaaen-Jensen (Norwegian University of Science and Technology, Trondheim, Norway) |
9:15 am - 9:45 am | Richard van Breemen (University of Illinois at Chicago, IL)
"Quantitative analysis of carotenoids using LC-MS-MS: Application to a clinical trial of prostate cancer chemoprevention by lycopene" |
9:45 am - 10:15 am | Klaus Albert (Universität Tübingen, Germany)
"Hyphenated techniques in carotenoid research" |
10:15 am - 10:45 am | C. Caris-Veyrat (INRA Avignon, France)
"Carotenoids derived products: from chemistry to biological relevance" |
10:45 am - 11:15 am | Coffee Break |
11:15 am | Group Photo |
11:30 am - 12:00 pm | Harry Klee (University of Florida, Gainesville, FL)
"Apocarotenoid volatiles in plants: synthesis and activities" |
12:00 pm - 12:30 pm | General Discussion: George Truscott (Keele University, UK) |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | ELECTRONIC STATES, PHOTOCHEMISTRY, AND PHOTOSYNTHESIS |
7:30 pm - 7:45 pm | Chair: Ana Moore (Arizona State University, Tempe, AZ) |
7:45 pm - 8:15 pm | Tomas Polivka (University of South Bohemia, Czech Republic)
"Carbonyl carotenoids in natural and artificial antenna systems" |
8:15 pm - 8:45 pm | Hideki Hashimoto (Osaka City University, Japan)
"Very early photophysics of carotenoids probed by sub-20 fs degenerated four-wave mixing (DFWM) spectroscopy" |
8:45 pm - 9:15 pm | Bruno Robert (Gif-sur-Yvette Cedex, France)
"Carotenoid molecules and Photoprotection in Photosynthesis" |
9:15 pm - 9:30 pm | General Discussion: Richard Cogdell (University of Glasgow, UK) |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | HUMAN HEALTH I: CAROTENOID METABOLITES, GENE REGULATION, AND CANCER A |
9:00 am - 9:15 am | Chair: Helmut Sies (Heinrich-Heine-Universitaet, Dusseldorf, Germany) |
9:15 am - 9:45 am | Xiang-Dong Wang (Jean Mayer USDA HNRCA at Tufts University, Boston)
"Molecular mechanisms underlying the biological activity of carotenoid metabolites" |
9:45 am - 10:15 am | Olaf Sommerburg (Children's University Hospital III, Heidelberg, Germany)
"Clinical need of Carotenoid Supplementation - How to find a way to do it safely?" |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:30 am | John Erdman, Jr. (University of Illinois, U.-C., IL)
"Lycopene, are lycopene metabolites bioactive?" |
11:30 am - 12:00 pm | Peter Gann (University of Illinois at Chicago, IL)
"Preliminary Results from a Phase II Trial of Lycopene-Rich Tomato Extract in Men with High-Grade Prostatic Intraepithelial Neoplasia (HGPIN)" |
12:00 pm - 12:30 pm | General Discussion: Adrian Wyss (DSM, Kaiseraugst, Switzerland) |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | HUMAN HEALTH II: CAROTENOID NUTRITION/BIOAVAILABILITY AN INTERNATIONAL PERSPECTIVE |
7:30 pm - 7:45 pm | Chair: Rob Russell (Jean Mayer USDA HNRCA at Tufts University, Boston) |
7:45 pm - 8:15 pm | Keith West (Johns Hopkins University, Baltimore, MD)
"Maternal Carotenoid Intake and Status in Rural South Asia: Implications for Health during Pregnancy and Infancy" |
8:15 pm - 8:45 pm | Richard Semba (Johns Hopkins U.)
"Relationship of carotenoids with muscle strength and physical performance in older adults" |
8:45 pm - 9:15 pm | Guangwen Tang (Jean Mayer USDA HNRCA at Tufts University, Boston)
"Vitamin A value of plant foods" |
9:15 pm - 9:30 pm | General Discussion: TBA |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | HUMAN HEALTH III: CAROTENOIDS IN THE EYE |
9:00 am - 9:15 am | Chair: Erik van Kuijk (University of Texas Medical Branch, Galveston, TX) |
9:15 am - 9:45 am | Julie Mares (University of Madison, Wisconsin)
"Impact of a long-term, low-fat, high fruit and vegetable diet, and other health and medical attributes on retinal macular pigment optical density in older women" |
9:45 am - 10:15 am | Malgorzata Rozanowska (Cardiff University, UK)
"Susceptibility of lutein do iron-mediated degradation and blue light-induced reactivity of the degradation products" |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:30 am | Paul Bernstein (University of Utah, Salt Lake City, UT)
"Vertebrate and Invertebrate Carotenoid-Binding Proteins" |
11:30 am - 12:00 pm | Emily Chew (NEI, Washington, D.C.)
"Long-term Follow-up of AREDS1 and Design of AREDS2" |
12:00 pm - 12:30 pm | General Discussion: Wolfgang Schalch (DSM, Kaiseraugst, Switzerland) |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | CAROTENOIDS IN HUMAN HEALTH IV: CAROTENOIDS, METABOLITES, GENETIC REGULATION AND CANCER B |
7:30 pm - 7:45 pm | Chair: Yoav Sharoni (Ben-Gurion University, Israel) |
7:45 pm - 8:15 pm | Margaret Wright (NCI, Washington, D.C.)
"Effects of Beta-carotene supplementation on molecular markers of lung carcinogenesis in male smokers: results from the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study" |
8:15 pm - 8:40 pm | Ouliana Ziouzenkova (Brigham and Women's Hospital, Boston)
"Asymmetric cleavage of beta-carotene yields a transcriptional PPAR and RXR repressor" |
8:40 pm - 9:05 pm | Joseph Levy (Ben-Gurion University, Israel)
"Epigenetic regulation in cancer prevention by carotenoid derivatives" |
9:05 pm - 9:30 pm | General Discussion: Joseph Levy (Ben-Gurion University, Israel) |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | CAROTENOIDS IN NATURE: PLANT BIOSYNTHESIS AND OCCURRENCE IN ANIMALS |
9:00 am - 9:15 am | Chair: Jonathan Blount (University of Exeter, Cornwall Campus, UK) |
9:15 am - 9:45 am | Claudia Schmidt-Dannert (University of Madison, Wisconsin)
"Making and breaking of carotenoids in engineered cells" |
9:45 am - 10:15 am | Eleanore Wurtzel (Lehman College, CUNY, New York)
"Regulation of provitamin A carotenoid accumulation in cereal crops" |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:30 am | Kevin McGraw (Arizona State University, Tempe, AZ)
"Carotenoid partitioning among body tissues in an avian model species: implications for trade-offs and differential functions" |
11:30 am - 12:00 pm | Kozo Tsuchida (National Inst. Infectious Diseases, Tokyo, Japan)
"Intracellular carotenoid transport by the Yellow blood ( Y ) gene of silkworm" |
12:00 pm - 12:30 pm | General Discussion: TBA |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 8:00 pm | Notable Young Investigator Presentations |
| Norman Krinsky (Tufts University, Boston, Mass) & Harry Frank (University of Connecticut, Storrs, Connecticut) |
8:00 pm - 9:30 pm | KEYNOTE LECTURE: CAROTENOID OXIDASES |
8:00 pm - 8:15 pm | Discussion Leader: John Erdman, Jr. (University of Illinois, U.-C., IL) |
8:15 pm - 9:00 pm | Johannes von Lintig (University of Freiberg, Germany)
"β-Carotene oxidase, discovery, functions, and prospects" |
9:00 pm - 9:30 pm | General Discussion: Harry Frank (University of Connecticut, Storrs, Connecticut) |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |