The Developmental Origins of Cartilage Disease

The Gordon Research Seminar on Cartilage Biology and Pathology provides a unique platform for early career researchers to discuss their work with peers working in the global field. Organized and led by early-career scientists, this meeting provides an informal environment to generate meaningful discussion of cutting-edge research, and an opportunity to network with other trainees. The meeting will cover mechanisms underpinning cartilage development, maintenance, and disease, with a focus on the developmental origin of cartilage pathologies. Formation and preservation of healthy cartilage is crucial for many aspects of the human skeleton, including synovial joints, intervertebral discs, and growth plates. A deeper understanding of how the fine-tuning of cartilage growth in early life contributes to pathologic changes will serve to advance clinically unmet needs for both congenital- and age-related cartilage disease therapies. This two-day meeting will address these issues from multiple angles including biology, genetics, and tissue engineering with the hope of launching a progressive dialogue that advances the field through the sharing of data and establishment of international collaborations.