Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Impact of Environmental Stressors on the Dopaminergic System
Discussion Leader: Patricia Janak (Johns Hopkins University, USA)
3:45 pm - 3:50 pm
Opening Remarks
3:50 pm - 4:05 pm
Abigail Schindler (University of Washington, USA)
"Persistent Dopaminergic and Behavioral Dysfunction Following Blast Exposure in Mice and Combat Veterans"
4:05 pm - 4:10 pm
Discussion
4:10 pm - 4:25 pm
Millie Rincon-Cortes (University of Pittsburgh, USA)
"Stress and Postpartum Effects on the Dopamine System"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Neurobiology of Motivated Behaviors: Multiple Circuits and Neurotransmitter Systems
Discussion Leaders: Michael Saddoris (University of Colorado Boulder, USA) and Lauren Burgeno (University of Washington, USA)
7:30 pm - 7:45 pm
Anne Collins (University of California, Los Angeles, USA)
"Pause, Collaboration, and Listen: How Nucleus Accumbens Acetylcholine Modulates Cue-Evoked Dopamine to Regulate Cue-Motivated Reward Seeking"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Dan Covey (University of Maryland, Baltimore, USA)
"Endocannabinoid Synthesis by Dopamine Neurons Controls Cue-Directed Reinforcement and Motivation"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Jocelyn Richard (Johns Hopkins University, USA)
"Ventral Pallidal Encoding of Reward Seeking Depends on the Underlying Associative Structure"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Vivien Zell (University of California, San Diego, USA)
"Do Ventral Tegmental Area Glutamate Neurons Drive Reinforcement Independent of Dopamine?"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Luke Coddington (Janelia Research Campus, Howard Hughes Medical Institute, USA)
"Midbrain Dopamine Neurons Encode Predictions During Action Initiation"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Zachary Brodnik (Drexel University, USA)
"Cocaine Potency at the Dopamine Transporter Is Determined by Dopamine Neuron Activation"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Pathological Implications of Catecholaminergic Disregulation / Mentorship Component: NIH Fellowships Discussion
Discussion Leader: Erin Calipari (Icahn School of Medicine at Mount Sinai, USA)
9:00 am - 9:15 am
Thomas Steinkellner (University of California, San Diego, USA)
"Selective Vulnerability of Substantia Nigra Dopamine Neurons to VGLUT2"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Arin Pamukcu (Northwestern University, USA)
"Alteration of Inputs form the Subthalamic Nucleus (STN) to the External Globus Pallidus (GPe) in Parkinson's Disease"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Lauren Reynolds (McGill University, Canada)
"Drugs of Abuse Disrupt DCC-Dependent Dopamine Axon Targeting in Adolescence"
9:55 am - 10:00 am
Discussion
10:00 am - 10:50 am
Roger Sorensen (National Institute on Drug Abuse, NIH / U.S. Department of Health and Human Services, USA)
"NIH Fellowships Discussion"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Circuit Mechanisms Governing the Noradrenergic Control of Behavior
Discussion Leader: David Weinshenker (Emory University School of Medicine, USA)
1:30 pm - 1:45 pm
Kirsten Porter-Stransky (Emory University, USA)
"Noradrenergic Transmission in the Ventral Periaqueductal Gray Modulates Wakefulness"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Jacki Rorabaugh (Emory University, USA)
"Chemogenetic Locus Coeruleus Activation Restores Reversal Learning in a Rat Model of Alzheimer's Disease"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Nicholas Harris (Vanderbilt University, USA)
"Uncovering the Excitatory Roles of Postsynaptic a2A-Adrenergic Receptors Within the Bed Nucleus of the Stria Terminalis"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
