Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
The Locus Coeruleus: Noradrenergic Regulation of Behavior
Discussion Leader: Lindsay Schwarz (St. Jude Children's Research Hospital, USA)
3:45 pm - 3:50 pm
Opening Remarks
3:50 pm - 4:05 pm
Mohsen Omrani (Brain Health Institute, Rutgers University, USA)
"Locus Coeruleus Activity in a Classical Conditioning Task"
4:05 pm - 4:10 pm
Discussion
4:10 pm - 4:25 pm
Natale Sciolino (National Institute of Environmental Health Sciences, NIH, USA)
"A Role for the Locus Coeruleus in the Modulation of Feeding"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Circuit Mechanisms: Dopaminergic Regulation of Learning
Discussion Leader: Joshua Berke (University of California, San Francisco, USA)
7:30 pm - 7:45 pm
David Ottenheimer (Johns Hopkins University, USA)
"Ventral Pallidum: A Critical Node for Value Computations in the Mesolimbic Circuit"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Dan Covey (University of Maryland, Baltimore, USA)
"Accumbal Dopamine Release Tracks the Expectation of Dopamine Neuron-Mediated Reinforcement"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Nick Hollon (Salk Institute for Biological Studies, USA)
"Action-Specific Suppression of Nigrostriatal Dopamine Release by Goal-Directed Behavior"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Munir Kutlu (Vanderbilt University School of Medicine, USA)
"A Novel Framework for Diametric Stimulus Encoding in the Nucleus Accumbens"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Taylor Stowe (Wake Forest School of Medicine, USA)
"Time-of-Day Variation in Reward-Associated and Learning Behaviors and in Rapid Dopamine Signaling"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Rebekah Evans (National Institutes of Health, USA)
"A Dendrite-Specific Striatonigral Circuit Facilitates Dopamine Rebound"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Dopaminergic Dysregulation: Implications for Addiction / Mentorship Component: NIH Fellowships
Discussion Leader: Jocelyn Richard (University of Minnesota, USA)
9:00 am - 9:15 am
Lauren DePoy (University of Pittsburgh, USA)
"Circadian- and Sex-Dependent Increases in Intravenous Cocaine Self-Administration in Npas2 Mutant Mice"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Lauren Burgeno (University of Oxford, United Kingdom)
"Diametric Changes in Ventral Striatal Dopamine Release Underlie Drug-Taking and Drug-Seeking Behaviors"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Tamara Markovic (Washington University in St. Louis, USA)
"Dissecting Dopamine Pathways Altered by Pain-Induced Dysfunction in Opioid Signaling"
9:55 am - 10:00 am
Discussion
10:00 am - 10:55 am
Roger Sorensen (National Institute on Drug Abuse, NIH, USA)
"A Discussion of NIH Fellowship Opportunities"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Synaptic Mechanisms: Regulation of Cellular Dynamics
Discussion Leader: Gary Aston-Jones (Rutgers Brain Health Institute, USA)
1:30 pm - 1:45 pm
Dennis Burke (National Institute on Alcohol Abuse and Alcoholism, NIH, USA)
"Dopamine Receptor Independent Actions of Dopamine on Medium Spiny Neuron Synaptic Transmission in the Nucleus Accumbens"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Michelle Corkrum (University of Minnesota, USA)
"Astrocytes Mediate Dopamine Neuromodulation in the Nucleus Accumbens"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Polina Kosillo (University of California, Berkeley, USA)
"mTORC1 and mTORC2 Differentially Control the Structure and Output of Midbrain Dopamine Neurons"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
