Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
Neuronal Signaling and Molecular Substrates of Catecholamine Systems
Discussion Leader: Eric Szelenyi (University of Washington, United States)
3:15 pm - 3:20 pm
Introduction by Discussion Leader
3:20 pm - 3:35 pm
Rianne Stowell (University of Rochester, United States)
"Frontal Cortical Microglia Respond to Dopaminergic Signals from the Adolescent Mesofrontal Circuit"
3:35 pm - 3:40 pm
Discussion
3:40 pm - 3:55 pm
Darshana Kapri (Tata Institute of Fundamental Research, India)
"Norepinephrine Regulates Mitochondrial Biogenesis and Function in the Hippocampus"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Catecholamine Systems in Reward and Learning
Discussion Leader: Ali Mohebi (University of California, San Francisco, United States)
5:30 pm - 5:45 pm
Carla Golden (New York University, United States)
"Estrogenic Gain Control of Reward Prediction Errors and Learning"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
Monica Dawes (Wake Forest University School of Medicine, United States)
"Methamphetamine and Fentanyl Co- Self-Administration Modifies Fentanyl Taking and Exacerbates Mesolimbic Dopamine Deficits"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
Juan Enriquez Traba (National Institute of Mental Health, United States)
"Dissociable Control of Motivation and Goal-Directed Behavior by Distinct Ventral Striatal Dopamine Receptors"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Arthur Godino (Icahn School of Medicine at Mount Sinai, United States)
"Dopaminoceptive D1 and D2 Neurons in Ventral Hippocampus Arbitrate Approach and Avoidance in Anxiety"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Cameron Ogg (St. Jude Children's Research Hospital, United States)
"Dynamic Locus Coeruleus Activity Affects the Organization of Orbitofrontal Cortex Neural Ensembles and Promotes Behavioral Flexibility"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Elizabeth Doncheck (Medical University of South Carolina, United States)
"Resolving Prefrontal Cortical Activity Dynamics and Noradrenergic Modulation of Relapse to Opioid Seeking"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Catecholamine Systems Dysfunction in Disease States
Discussion Leaders: Violet Kimble (Yale University, United States) and Naveen Nagarajan (University of Utah, United States)
9:00 am - 9:15 am
Nathaniel Jones (University of Ottawa, Canada)
"Chronic in vivo Two-Photon Imaging of Cortical Noradrenaline Reveals Altered Spatiotemporal Release Dynamics During Motor Learning in a Mouse Model of Autism"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Kelly Clemenza (Albert Einstein College of Medicine, United States)
"A Novel Gene Therapy-Based Approach for Lasting Protection from Opioid Use Disorder"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Nicolette Moya (Northwestern University, United States)
"The Role of Nigrostriatal and Striatal Cell Subtype Signaling in Behavioral Impairments Related to Schizophrenia"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Lauren Reynolds (CNRS - ESPCI Paris, France)
"Nicotine in Adolescence Freezes Dopamine Circuits in an Immature State"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Emily "Gracie" Peck (Wake Forest University School of Medicine, United States)
"Syanaptogyrin-3 as a Novel Modulator of the Dopamine Transporter in Cocaine Abuse Vulnerability"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Marine Salery (Icahn School of Medicine Mount Sinai, United States)
"Capturing and Profiling Cocaine-Recruited Arc Neuronal Ensembles Encoding Drug-Context Associations in the Nucleus Accumbens"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Unraveling the Physiology of Catecholamine Circuits
Discussion Leader: Jacquelyn Tomaio (Advanced Science Research Center at Graduate Center, CUNY, United States)
1:30 pm - 1:45 pm
Suzanne Nolan (Vanderbilt University, United States)
"Axonal and Somatodendritic Dopamine Dynamics Are Governed by Compartmentalized Experience-Dependent Mechanisms"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Aida Mohammadkhani (University of Calgary, Canada)
"Effects of Chronic Morphine on LH Orexin and Dynorphin Modulation of VTA Dopamine Neurons"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Adam Gordon-Fennell (University of Washington, United States)
"Dynamics of Lateral Hypothalamus GABA and Glutamate Neuron and Dopamine Release During Consummatory Behavior"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
