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Cell Biology of Megakaryocytes and Platelets (GRS)

Gordon-Merck Research Seminar

Establishing a Research Career in Platelet Biology and Hemostasis/Thrombosis

March 19 - 20, 2011
Chair Rudy Fuentes
Grand Galvez
2024 Seawall Boulevard
Galveston, Texas, United States
 Venue and Travel Information

Conference Description

The Gordon Research Seminar on Cell Biology of Megakaryocytes & Platelets is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The focus of this meeting is on the brightest young investigators (graduate students and post-docs) in the fields of megakaryopoiesis and platelet biology and their latest advances in understanding megakaryocyte and platelet formation and function in hemostasis/thrombosis. Through career oriented presentations and a round table discussion with both academic and pharmaceutical leaders in this field, this GKRS will also provide young researchers with valuable career advice from experts conducting basic, translational and pharmaceutical research.

Related Meeting

This GRC will be held in conjunction with the "Cell Biology of Megakaryocytes and Platelets" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Conference Program

SATURDAY
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmAn Academic Career in Megakaryocyte/Platelet Biology
3:45 pm - 4:15 pm Barry Coller (Rockefeller Institute)
"An academic career in translational platelet biology"
4:15 pm - 4:30 pm Discussion
4:30 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 8:15 pmCareer II
7:30 pm - 8:00 pm Elliott Barnathan (Centocor)
"Hemostasis/thrombosis Career Development in Industry"
8:00 pm - 8:15 pm Discussion
8:15 pm - 9:30 pmShort Presentations in Megakaryocyte/Platelet Biology
Discussion Leader: Mitchell Weiss (University of Pennsylvania)
8:15 pm - 8:30 pm Hui Huang (Children's Hospital Boston)
"Tyrosine Phosphorylation of Runx1 In Megakaryocytes by Src Family Kinases"
8:30 pm - 8:40 pm Discussion
8:40 pm - 8:55 pm Ronghua Meng (University of Pennsylvania)
"Slc35d3 regulates biogenesis of platelet dense granules from an early endosomal compartment"
8:55 pm - 9:05 pm Discussion
9:05 pm - 9:20 pm Teshell K. Green (Children's Hospital of Philadelphia)
"Understanding Ectopically Expressed Factor VIII (F8) in Megakaryocytes: Implications for Optimum Platelet-Delivered F8 Activity for Gene Therapy"
9:20 pm - 9:30 pm Discussion
SUNDAY
7:30 am - 8:30 amBreakfast
9:00 am - 10:40 amShort Presentations in Megakaryocyte/Platelet Biology II
Discussion Leader: Barry Coller (Rockefeller Institute)
9:00 am - 9:15 am Paul S. Hartley (University of Edinburgh)
"CLOCK regulates thrombopoietin expression and megakaryocyte development"
9:15 am - 9:25 am Discussion
9:25 am - 9:40 am Bethany Kerr (Cleveland Clinic Foundation)
"Platelet Alpha-Granules Sequester and Release the Tumor Secretome"
9:40 am - 9:50 am Discussion
9:50 am - 10:05 am Maxim A. Pimkin (Children's Hospital of Philadelphia)
"Lineage-specific GATA1 and TAL1 functions in erythromegakaryopoiesis revealed by genome-wide analysis of transcription factor chromatin occupancy and mRNA expression"
10:05 am - 10:15 am Discussion
10:15 am - 10:30 am Alexander Zaslavsky (University of Pennsylvania)
"Calcineurin signalling inhibits megakaryopoiesis"
10:30 am - 10:40 am Discussion
10:40 am - 12:30 pmPoster Session II
12:30 pmLunch
1:30 pm - 3:00 pmShort Presentations in Megakaryocyte/Platelet Biology III
Discussion Leader: Elliot Barnathan (Centocor)
1:30 pm - 1:45 pm Stephan C. Lindsey (University of Delaware)
"The Aryl Hydrocarbon Receptor (AhR) Modulates Megakaryocytic Polyploidization Through Interactions With Hes1"
1:45 pm - 1:55 pm Discussion
1:55 pm - 2:10 pm Jae-Won Shin (University of Pennsylvania)
"Myosin-II inhibition and soft 2D matrix maximize maturation of platelet-producing megakaryocytes"
2:10 pm - 2:20 pm Discussion
2:20 pm - 3:00 pmEvaluation Period
(Fill out GRS Evaluation Forms)
3:00 pmGordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm.

Contributors

Conference Links

Conference History Cell Biology of Megakaryocytes and Platelets
Additional Fee Info

Cell Biology of Megakaryocytes and Platelets
March 2 - 7, 2025


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