| SATURDAY |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | An Academic Career in Megakaryocyte/Platelet Biology |
| 3:45 pm - 4:15 pm | Barry Coller (Rockefeller Institute)
"An academic career in translational platelet biology" |
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 8:15 pm | Career II |
| 7:30 pm - 8:00 pm | Elliott Barnathan (Centocor)
"Hemostasis/thrombosis Career Development in Industry" |
| 8:00 pm - 8:15 pm | Discussion |
| 8:15 pm - 9:30 pm | Short Presentations in Megakaryocyte/Platelet Biology |
| Discussion Leader: Mitchell Weiss (University of Pennsylvania) |
| 8:15 pm - 8:30 pm | Hui Huang (Children's Hospital Boston)
"Tyrosine Phosphorylation of Runx1 In Megakaryocytes by Src Family Kinases" |
| 8:30 pm - 8:40 pm | Discussion |
| 8:40 pm - 8:55 pm | Ronghua Meng (University of Pennsylvania)
"Slc35d3 regulates biogenesis of platelet dense granules from an early endosomal compartment" |
| 8:55 pm - 9:05 pm | Discussion |
| 9:05 pm - 9:20 pm | Teshell K. Green (Children's Hospital of Philadelphia)
"Understanding Ectopically Expressed Factor VIII (F8) in Megakaryocytes: Implications for Optimum Platelet-Delivered F8 Activity for Gene Therapy" |
| 9:20 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 10:40 am | Short Presentations in Megakaryocyte/Platelet Biology II |
| Discussion Leader: Barry Coller (Rockefeller Institute) |
| 9:00 am - 9:15 am | Paul S. Hartley (University of Edinburgh)
"CLOCK regulates thrombopoietin expression and megakaryocyte development" |
| 9:15 am - 9:25 am | Discussion |
| 9:25 am - 9:40 am | Bethany Kerr (Cleveland Clinic Foundation)
"Platelet Alpha-Granules Sequester and Release the Tumor Secretome" |
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:05 am | Maxim A. Pimkin (Children's Hospital of Philadelphia)
"Lineage-specific GATA1 and TAL1 functions in erythromegakaryopoiesis revealed by genome-wide analysis of transcription factor chromatin occupancy and mRNA expression" |
| 10:05 am - 10:15 am | Discussion |
| 10:15 am - 10:30 am | Alexander Zaslavsky (University of Pennsylvania)
"Calcineurin signalling inhibits megakaryopoiesis" |
| 10:30 am - 10:40 am | Discussion |
| 10:40 am - 12:30 pm | Poster Session II |
| 12:30 pm | Lunch |
| 1:30 pm - 3:00 pm | Short Presentations in Megakaryocyte/Platelet Biology III |
| Discussion Leader: Elliot Barnathan (Centocor) |
| 1:30 pm - 1:45 pm | Stephan C. Lindsey (University of Delaware)
"The Aryl Hydrocarbon Receptor (AhR) Modulates Megakaryocytic Polyploidization Through Interactions With Hes1" |
| 1:45 pm - 1:55 pm | Discussion |
| 1:55 pm - 2:10 pm | Jae-Won Shin (University of Pennsylvania)
"Myosin-II inhibition and soft 2D matrix maximize maturation of platelet-producing megakaryocytes" |
| 2:10 pm - 2:20 pm | Discussion |
| 2:20 pm - 3:00 pm | Evaluation Period |
| (Fill out GRS Evaluation Forms) |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
