Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Metals in Host-Fungal Interactions
Discussion Leader: Karrera Djoko (The University of Queensland, Australia)
3:45 pm - 4:05 pm
Valeria Culotta (Johns Hopkins University, USA)
"Winning the Battle with Metals and ROS: Tales of a Successful Fungal Pathogen"
4:05 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
Edward Culbertson (Johns Hopkins School of Public Health, USA)
"Copper, Iron and Ceruloplasmin During Fungal Infection"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Metals in Host-Bacterial Interactions
Discussion Leader: Duncan Wilson (University of Aberdeen, United Kingdom)
7:30 pm - 7:50 pm
Jules Stephan (Massachusetts Institute of Technology, USA)
"Methionine Oxidation Increases the Protease Sensitivity of Calprotectin by Altering Its Oligomeric State"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Kyle Grim (University of Illinois at Urbana-Champaign, USA)
"The Metallophore Staphylopine Enables Staphylococcus aureus to Compete with the Host for Zinc and Overcome Nutritional Immunity"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Victoria Pederick (The University of Adelaide, Australia)
"The Role of Pht Proteins in Pneumococcal Zinc Acquisition"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Jiefei Wang (Indiana University Bloomington, USA)
"The Response of Acinetobacter baumannii to Human-Mediated Zinc Starvation"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Julia Quintana (Worcester Polytechnic Institute, USA)
"Dissecting Copper Distribution Networks in Pseudomonas aeruginosa "
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Maria Alessandra Martini (Durham University, United Kingdom)
"Modelling a Network of Metal Sensors"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Metals in Human Disease
Discussion Leader: Edward Culbertson (Johns Hopkins School of Public Health, USA)
9:00 am - 9:20 am
Vinit Shanbhag (University of Missouri, USA)
"Role for ATP7A Copper Transporter in Cisplatin Resistance, Tumorigenesis and Metastasis"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Subha Bakthavatsalam (Duke University, USA)
"Copper Prochelator as Prodrug for Prostate Cancer"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
Sayani Das (Tata Institute of Fundamental Research, India)
"Mn(II) Sensor Diaries: Stumbling upon a Hg(II) Sensor and What We Learn from It"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Lisa Cunden ( Massachusetts Institute of Technology, USA)
"Modulation of the Zn(II)-Binding and Functional Roles of S100A7 Through Its Intramolecular Disulfide Bonds"
10:25 am - 10:30 am
Discussion
10:30 am - 10:50 am
Viktoria Desiree Paul (Philipps-Universität Marburg, Germany)
"With a Little Help from My Friends: The Human YAE1D1-ORAOV1 Adaptor Complex Recruits the CIA Machinery to Facilitate Fe-S Cluster Incorporation into ABCE1"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Keynote Session: Metals in Eukaryotic Physiology
Discussion Leader: Vinit Shanbhag (University of Missouri, USA)
1:30 pm - 1:50 pm
Sven Freibert (Philipps-Universität Marburg, Germany)
"Structural and Functional Insights into Mitochondrial Fe/S Cluster Synthesis"
1:50 pm - 2:00 pm
Discussion
2:00 pm - 2:20 pm
Dennis Thiele (Duke University School of Medicine, USA)
"A Winding Journey from Yeast to Mammals Guided by Metals"
2:20 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
