Saturday
1:30 pm - 4:30 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Keynote Session: Metal Sensing and Homeostasis
Discussion Leader: Sven Freibert (Philipps-Universität Marburg, Germany)
3:15 pm - 3:45 pm
David Giedroc (Indiana University, USA)
"Fighting over Metals: Transition Metal Homeostasis in Bacterial Pathogens"
3:45 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Metals in Cellular Physiology
Discussion Leader: Joel Brandis (University of Maryland School of Pharmacy, USA)
5:30 pm - 5:45 pm
Cherish Taylor (The University of Texas at Austin, USA)
"Activity of SLC30A10 in the Brain Protects Against Manganese Neurotoxicity During Overexposure"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
Florelle Domart (University of Bordeaux, France)
"Correlating Super Resolution Microscopy with Synchrotron X-Ray Fluorescence Imaging to Study Metal Functions in Neuronal Cells"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
Jason Shapiro (Feinberg School of Medicine, Northwestern University, USA)
"Jumonji-C Histone Demethylases Are Cellular Iron Sensors Controlling mTORC1 Activity"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Ana Silva (ITQB NOVA, Portugal)
"Understanding the Biogenesis of c-type Cytochromes: Incorporation of Heme in the Polypeptide Chain"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Thomas Hercher (TU Braunschweig, Germany)
"Crosstalk Between the Biosynthesis Pathways for Moco and FeS-Clusters: Rehabilitating Yeast to Synthesize Moco"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Tessa Young (Durham University, United Kingdom)
"The Cobalt Delivery Pathway for Vitamin B12"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Strategies for Metal Acquisition and Virulence
Discussion Leader: Karina Baksh (University of Toronto, Canada)
9:00 am - 9:15 am
Corinna Probst (Duke University, USA)
"The Role of Cryptococcus neoformans Cu Homeostasis Machinery for Cell Wall Remodeling During Host Infection"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Clémentine Laffont (Aix-Marseille Université, France)
"The Very Ancient Roots of Nicotianamine: Discovery, Diversity, Evolution and Regulation of Nicotianamine-Based Metallophore"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Inês Trindade (Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA), Portugal)
"Unraveling the Mechanisms of Ferric-Siderophore Reduction: The Unforeseen Versatility of SfSIP, a Siderophore-Interacting Protein from Shewanella frigidimarina "
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Jacqueline Zaengle-Barone (Duke University, USA)
"The Role of Copper in the Mode of Action of a β-Lactamase-Activated Antibacterial Prochelator"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Jessica Sheldon (Vanderbilt University Medical Center, USA)
"The Role of Histamine in Iron Acquisition by Acinetobacter baumannii "
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Cassandra Nelson (University of Maryland, Baltimore, USA)
"Response of Pseudomonas aeruginosa to Calprotectin-Mediated Multi-Metal Sequestration"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career and Networking Panel Discussion
Discussion Leader: Elizabeth Robinson (University of Maryland School of Pharmacy, USA)
1:30 pm - 2:30 pm
Panel Discussion
What's Next? Exploring Careers Beyond Your Graduate and Post-Doctoral Training
Amanda Bird (The Ohio State University, USA)
Iqbal Hamza (University of Maryland, USA)
Fiona Marston (Centre of Excellence in Infectious Diseases Research, United Kingdom)
Neil Withers (Chemistry World, Royal Society of Chemistry, United Kingdom)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes