| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:00 pm | Welcome and Keynote Address |
| Pietro DeCamilli (Yale University)
"Endocytic mechanisms at the synapse" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | DENDRITIC mRNA AND FRAGILE X SYNDROME |
| Discussion Leader: William Greenough (University of Illinois) |
| 9:00 am - 9:30 am | William Greenough (University of Illinois)
"Overview: Molecular and cell biology of Fragile X Syndrome" |
| 9:30 am - 10:00 am | Claudia Bagni (University of Rome)
"mRNA translation at synapses: a common role for the Fragile X Mental Retardation Protein and the non coding RNA BC1" |
| 10:00 am - 10:45 am | Photo & Coffee Break |
| 10:45 am - 11:15 am | Gary Bassell (Albert Einstein College of Medicine)
"RNA binding proteins in synaptic development, plasticity and
Fragile X" |
| 11:15 am - 12:00 pm | Short Talks |
| Stephanie Cemen (University of Illinois)
"Phosphorylation influences the translation state of FMRP-associated polyribosomes" |
| Jennifer Darnell (Rockefeller University)
"FMRP associates with brain polyribosomes through KH2 domain binding to a kissing complex RNA" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | SYNAPTIC CYTOMATRIX & CELL ADHESION |
| Discussion Leader: Oleg Shupliakov (Karolinska Institute) |
| 7:30 pm - 8:00 pm | Britta Qualmann (Leibniz Institute for Neurobiology)
"Interconnection of the actin cytoskeleton to pre- and postsynaptic cytomatrix components" |
| 8:00 pm - 8:15 pm | Craig Garner (Stanford University)
"Biogenesis of active zone precursor vesicles" |
| 8:15 pm - 8:45 pm | Short Talks |
| Viviana Torres (Stanford University)
"Mechanisms of active zone formation" |
| Toshihisa Otsuka (KAN Research Institute, Kyoto)
"Biochemistry of the presynaptic active zone" |
| 8:45 pm - 9:15 pm | Deanna Benson (Mount Sinai School of Medicine)
"Multifunctional cadherins during outgrowth and synaptogenesis" |
| 9:15 pm - 9:30 pm | Short Talk |
| Kentaro Abe (RIKEN)
"Stability of dendritic spines and synaptic contacts is controlled by alphaN-catenin" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | ACTIN CYTOSKELETON AT GROWTH CONES & SYNAPSES |
| Discussion Leader: James Bamburg (Colorado State) |
| 9:00 am - 9:30 am | Marie-France Carlier (CNRS)
"Control of actin assembly dynamics in actin-based motility, a biomimetic approach" |
| 9:30 am - 10:00 am | Paul Forscher (Yale University)
"Cytoskeletal protein dynamics and signaling during axon
guidance events" |
| 10:00 am - 10:30 am | Coffee Break |
| 10:30 am - 10:45 am | Short Talk |
| Lorene Lanier (University of Minnesota)
"ARP2/3 function in growth cone motility: proof that a growth cone is not juts a fibroblast on a leash" |
| 10:45 am - 11:15 am | Tomoaki Shirao (Gunma University)
"Genetic and activity-dependent control of drebrin clustering in spine formation" |
| 11:15 am - 12:15 pm | Short Talks |
| Ann-Marie Craig (Washington Univ. School of Medicine)
"Regulated synaptic protein mobility in dendritic spines" |
| Bonnie Firestein (Rutgers University)
"The role of cypin in regulating dendrite number" |
| Short Talks - Ubiquitin Mini-Session |
| Marcie Colledge (UT Southwestern)
"Ubiquitination at the postsynaptic density" |
| Daniel Pak (Georgetown University)
"Discarding synaptic proteins in the SNK disposal" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | UBIQUITIN, PROTEIN DEGRADATION & NEURONAL FUNCTION |
| Discussion Leader: Mike Ehlers (Duke University) |
| 7:30 pm - 8:00 pm | Mike Ehlers (Duke University)
"Ubiquitin in the deconstruction of synapses" |
| 8:00 pm - 8:30 pm | Christine Holt (University of Cambridge)
"Degradation and endocytosis in growth cone chemotropic guidance" |
| 8:30 pm - 9:00 pm | Joshua Kaplan (Mass. General, Harvard)
"Ubiquitin-mediated regulation of synaptic transmission in C. elegans" |
| 9:00 pm - 9:30 pm | Erin Schuman (Cal Tech)
"Rapid requirement for the proteasome in AMPA receptor endocytosis" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | FUSION PORES AND VESICLE CYCLING |
| Discussion Leader: Reinhard Jahn (Max-Planck-Institute) |
| 9:00 am - 9:30 am | Haruo Kasai (National Institute for Physiological Science, Okazaki)
"Two-photon excitation imaging of exocytosis and endocytosis" |
| 9:30 am - 10:00 am | Guy Rutter (University of Bristol)
"What drives insulin secretory vesicle dynamics and fusion at the plasma membrane?" |
| 10:00 am - 10:30 am | William Betz (University of Colorado)
"Synaptic vesicle pools in frog motor neuron terminals" |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 12:30 pm | VESICLE DOCKING AND FUSION |
| Discussion Leader: Ling-Gang Wu (NIH) |
| 11:00 am - 11:30 am | Wolf Almers (Vollum Institute)
"Tracking SNARE complex formation in live cells by intramolecular FRET" |
| 11:30 am - 12:00 pm | Nils Brose (Max-Planck Institute)
"Regulation of synaptic short term plasticity by second messengers: Molecules and mechanisms" |
| 12:00 pm - 12:30 pm | Short Talks |
| Robin Hiesinger (Baylor)
"The role of the V0 v-ATPase complex in synaptic transmission" |
| Jakob Soerensen (Max-Planck-Institute)
"The SNARE complex affects different phases of exocytosis in chromaffin cells" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | LIPID SIGNALING MECHANISMS AT THE SYNAPSE |
| Discussion Leader: Janet Richmond (Univ. Illinois, Chicago) |
| 7:30 pm - 8:00 pm | Mattijs Verhage (Center for Neurogenomics & Cognitive Research)
"The molecular mechanisms that harbour secretory vesicles at their target" |
| 8:00 pm - 8:30 pm | Erik Jorgensen (University of Utah)
"Synaptic vesicle exocytosis in C. elegans" |
| 8:30 pm - 9:00 pm | Kendal Broadie (Vanderbilt University)
"New Drosophila mutants reveal essential lipid signaling mechanisms at the synapse" |
| 9:00 pm - 9:30 pm | Short Talks |
| Jiang Liu (University of Michigan)
"Syntaxin1A-Munc18 interactions in vivo: analysis by FRET" |
| Andrea M. Holgado (University of Illinois at Chicago)
"Role of the C. elegans tomosyn homolog (TOM-1) in synaptic transmission" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | LONG-TERM SYNAPTIC MODIFICATION |
| Discussion Leader: Jeff Lichtman (Washington Univ. St. Louis) |
| 9:00 am - 9:30 am | Craig Bailey (Columbia University College of Physicians & Surgeons)
"Synaptic growth, synaptic maintenance and the persistence of long-term memory storage" |
| 9:30 am - 10:00 am | Anne McKinney (University of Zurich)
"The role of glutamatergic transmission in dendritic spine dynamics" |
| 10:00 am - 10:30 am | Coffee Break |
| 10:30 am - 11:00 am | Kristen Harris (Medical College of Georgia)
"Transendocytosis via dendritic spinules" |
| 11:00 am - 11:30 am | Mary Kennedy (Cal Tech)
"Effects of synaptic signaling machinery on neuronal apoptosis" |
| 11:30 am - 12:15 pm | Short Talks |
| Camin Dean (U. Wisconsin)
"Neuroligin/Neurexin mediated synapse formation in the CNS" |
| Adi Mizrahi (Duke University)
"In vivo imaging of dendritic trees in the mouse olfactory bulb" |
| Anthony Holtmaat (Cold Spring Harbor Laboratory)
"Spine turnover and stability in the neocortex" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Banquet |
| 8:00 pm - 9:00 pm | Special Lecture |
| Jeff Lichtman (Washington Univ. St. Louis) |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
