SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Session |
| Discussion Leader: Graeme Davis (UCSF, San Francisco, CA) |
7:40 pm - 8:20 pm | Catherine DuLac (HHMI, Harvard University, Boston, MA)
"Neurons Controlling Opposing Social Behaviors" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Yuh-Nung Jan (HHMI, UCSF, San Francisco CA)
"Molecular Mechanisms of Axon and Dendrite Remodeling"
|
9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Developmental Mechanisms |
| Discussion Leader: Esther Stoeckli (ETH, Zurich, Switzerland) |
9:00 am - 9:25 am | Madeline Lancaster (Institute of Molecular Biotechnology, Vienna, Austria) |
9:25 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Xiaowei Zhuang (HHMI, Harvard University, Boston MA)
"A Periodic Submembrane Cytoskeletal Structure in Axons"
|
10:05 am - 10:20 am | Discussion |
10:20 am | Group Photo / Coffee Break |
10:50 am - 11:15 am | Esther Stoeckli (ETH, Zurich, Switzerland)
"Transcription, Translation, and Trafficking in Axonal Behavior at Choice Points"
|
11:15 am - 11:30 am | Discussion |
11:30 am - 11:55 am | Beth Stevens (Harvard University, Boston MA)
"Wiring and Unwiring the Brain: Role of Microglia and the Complement Cascade"
|
11:55 am - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Shiri Yaniv (Weizmann Institute of Science)
"NO Acts as a Molecular Switch in the Transition Between Developmental Axon Pruning and Regrowth"
|
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Models of Disease |
| Discussion Leader: Claudia Bagni (VIB, University of Leuven, Leuven, Belgium) |
7:30 pm - 7:55 pm | Claudia Bagni (VIB, University of Leuven, Leuven, Belgium)
"Fragile X and Autism: Shared Pathways at Synapses"
|
7:55 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Mike Ehlers (Pfizer, Cambridge, MA)
"Synaptic Control of Secretory Trafficking in Dendrites" |
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Anirvan Ghosh (Roche, Basel, Switzerland; UCSD, San Diego, CA)
"Regulation of Synaptic Connectivity and Function by LRR Proteins" |
9:15 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Synaptic Transmission |
| Discussion Leader: Christian Rosenmund (Charité, Berlin, Germany) |
9:00 am - 9:25 am | Takeshi Sakaba (Doshisha University, Kyoto, Japan)
"Presynaptic Recordings from an Inhibitory Terminal"
|
9:25 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Christian Rosenmund (Charité, Berlin, Germany)
"The Role of SNARE's in Vesicle Priming and Regulation of Release Probability" |
10:05 am - 10:20 am | Discussion |
10:20 am | Coffee Break |
10:50 am - 11:15 am | Erik Jorgensen (HHMI, University of Utah, Salt Lake City, UT)
"Ultrafast Endocytosis"
|
11:15 am - 11:30 am | Discussion |
11:30 am - 11:55 am | Matthijs Verhage (Free University, Amsterdam, The Netherlands)
"Trafficking and Fusion of Dense Core Vesicles in Mammalian CNS Neurons"
|
11:55 am - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Josta Kevenaar (Utrecht University)
"Kinesin Binding Protein Provides a Novel Mechanism for Regulating Kinesin Motor Activity"
|
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Glial Biology / Keynote Lecture |
| Discussion Leader: Nils Brose (Max Planck Insitute of Experimental Medicine, Goettingen, Germany) |
7:30 pm - 7:55 pm | Klaus Nave (Max Planck Institute of Experimental Medicine, Goettingen, Germany)
"Myelination and Glial Support of Long Axons"
|
7:55 pm - 8:10 pm | Discussion |
8:10 pm - 9:10 pm | Keynote Lecture: Thomas Südhof (HHMI, Stanford University, Palo Alto, CA)
"Neurexins and Their Ligands in Synapse Formation and Function"
|
9:10 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Neural Plasticity |
| Discussion Leader: Gina Turrigiano (Brandeis University, Boston, MA) |
9:00 am - 9:25 am | Lu Chen (Stanford University, Palo Alto, CA)
"Interplay Between Synaptic RA Signaling and LTP"
|
9:25 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Susumu Tomita (Yale University, New Haven, CT)
"Molecular Machinery to Determine Synaptic Strength"
|
10:05 am - 10:20 am | Discussion |
10:20 am | Coffee Break |
10:50 am - 11:15 am | Gina Turrigiano (Brandeis University, Boston, MA)
"Transcriptional Control of AMPAR Trafficking During Synaptic Scaling Up"
|
11:15 am - 11:30 am | Discussion |
11:30 am - 11:55 am | Kelsey Martin (UCLA, Los Angeles, CA) |
11:55 am - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Andrea Stavoe (Yale University)
"Synaptic Vesicle Clustering Requires Autophagy Pathway Components in C. elegans"
|
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Cellular Physiology |
| Discussion Leader: Tim Ryan (Weill Cornell Medical School, New York, NY) |
7:30 pm - 7:55 pm | Tom Schwarz (Harvard University, Boston MA)
"Regulating the Dynamics of Neuronal Mitochondria"
|
7:55 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Ryohei Yasuda (Max Planck Florida Institute, Jupiter, FL)
"Spatiotemporal Dynamics of Biochemical Signaling in Neurons"
|
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Tim Ryan (Weill Cornell Medical School, New York, NY)
"The Control of Calcium Channel Function at Nerve Terminals"
|
9:15 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Degeneration and Regeneration |
| Discussion Leader: Yishi Jin (HHMI, UCSD, La Jolla, CA) |
9:00 am - 9:25 am | Barris Bingol (Genentech, South San Francisco, CA)
"Mitophagy and Parkinson's Disease" |
9:25 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Aaron Gitler (Stanford University, Palo Alto, CA)
"Yeast Genetic Screen Reveals Novel Insights into Mechanisms of Parkinson's Disease"
|
10:05 am - 10:20 am | Discussion |
10:20 am | Coffee Break |
10:50 am - 11:15 am | Mark Freeman (HHMI, University of Massachusetts, Worcester, MA)
"Genetic Regulation of Axon Maintenance and Degeneration"
|
11:15 am - 11:30 am | Discussion |
11:30 am - 11:55 am | Yishi Jin (HHMI, UCSD, La Jolla, CA)
"Molecular Dynamics in Injured Axons: Views from C. elegans"
|
11:55 am - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | L. Niels Cornelisse (Center for Neurogenomics and Cognitive Research (CNCR))
"Additive Regulatory Effects on the Energy Barrier of Synaptic Vesicle Fusion Cause Supralinear Effects on the Vesicle Fusion Rate" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Protein Trafficking |
| Discussion Leader: Erika Holzbaur (University of Pennsylvania, Philadelphia, PA) |
7:30 pm - 7:55 pm | Volker Haucke (FMP, Berlin, Germany)
"Where the Tortoise and the Hare Meet: The Role of Clathrin/AP-2 in Synaptic Vesicle Cycling"
|
7:55 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Robert Edwards (UCSF, San Francisco, CA)
"Biogenesis of the Regulated Secretory Pathway"
|
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Erika Holzbaur (University of Pennsylvania, Philadelphia, PA)
"Axonal Transport Dynamics and the Maintenance of Neuronal Homeostasis"
|
9:15 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |