Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: The Cell Biology Revolution in Neuroscience
7:40 pm - 8:25 pm
"Exocytosis of Synaptic Vesicles: 25 Years of Molecular Research"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 9:20 pm
"Towards a Cell Biology of Synapse Formation"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Organelle, Protein and RNA Trafficking
9:00 am - 9:25 am
"Making, Breaking and Parking Neuronal Mitochondria"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"The ER-Mitochondria Interface Is Critical for Calcium Homeostasis and Synaptic Function in Mammalian Neurons"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Polarity of Neuronal Membrane Traffic Requires Sorting of Kinesin Motor-Cargo During Entry into Dendrites by a Microtubule-Associated Septin"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Group Photo / Coffee Break
11:00 am - 11:25 am
"Neuroaxonal Dystrophy and Autophagy Defects Caused by Failure of AP-4-Mediated Export of ATG9A from the TGN"
11:25 am - 11:35 am
Discussion
11:35 am - 12:00 pm
"Axonal Transport of Actin: A New Trafficking Paradigm"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:20 pm
"Opioid Receptors Reveal a Parallel Cycle of Regulated Presynaptic Membrane Trafficking"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Transcriptional, Translational and Posttranslational Regulation
7:30 pm - 7:55 pm
"Epigenetic Regulation of Axon Regeneration: The Role of Gene Repression"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"Single-Cell Transcriptomics and the Study of the Brain"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"Single Molecule Analyses of Endogenous β-Actin mRNA Trafficking Reveal a Mechanism for Compartmentalised mRNA Localization in Axons"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"The Tubulin Code: How Cells Encode Specificity into Their Microtubule Networks"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Synapse Dynamics and Function
9:00 am - 9:25 am
"Mechanisms of Presynaptic Biogenesis and Function"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Shaping Membrane During Ultrafast Endocytosis"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Ca2+ -Dependent Control of the Synaptic Vesicle Replenishment Rate"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"Metabolic Basis of Synaptic Performance"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Visualizing Compensatory Endocytosis in 'Xenapses', TIRF-Amenable Synapses"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"SynGO: Evidence-Based Annotation of Synaptic Genes"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Exocytosis Frozen in Time: Synchronous, Asynchronous and Multivesicular Release"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:55 pm
"Trash Talk: C. elegans Neurons Throw out Garbage (Aggregates, Mitochondria)"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"Excitatory Neurogliomal Synapses Drive Brain Tumor Proliferation"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"Gamma-Neurexin and Frizzled Mediate Parallel Synaptogenic Pathways Antagonized by Receptor Endocytosis"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Trafficking Mechanisms for Neuronal Extracellular Vesicle Cargoes"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Synaptic Alignment and Connectivity
9:00 am - 9:25 am
"Mechanism of Nanoscale Transsynaptic Alignment"
9:25 am - 9:35 am
Discussion
9:35 am - 9:45 am
"Filopodia Conduct Target Selection in Cortical Neurons Using Differences in Signal Kinetics of a Single Kinase"
9:45 am - 9:50 am
Discussion
9:50 am - 10:15 am
"Assembly and Function of the Presynaptic Active Zone"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"An Input-Specific Synaptic Organizing Complex Controls Mossy Fiber Synapse Development and Function"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"SALM1 Controls Synapse Development by Regulating F-Actin/PIP2-Dependent Clustering of Neurexin"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Mitochondrial Dynamics and Dendritic Computation in the Drosophila Visual System"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"An Activity-Dependent Autocrine BMP Pathway Organizes Presynaptic Terminals at the Drosophila NMJ"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Homeostasis, Aggregation and Autophagy
7:30 pm - 7:55 pm
"Oligodendroglial Autophagy"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"Energy Homeostasis in Health and Disease: Importance of Remobilizing Mitochondria in Distal Axons"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"Expression of WIPI2B Counteracts Age-Related Decline in Autophagosome Biogenesis in Neurons"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:05 pm
"Regulation of Vesicle Acidification at the Neuronal Synapse"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"An Activity-Regulated Septin Subunit Is Required for the Entry of Endoplasmic Reticulum into Dendritic Spines and Spatial Discrimination"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cell Biology of Neuronal Degeneration and Regeneration
9:00 am - 9:25 am
"Distinct Roles of Multiple RNA-Mediated Pathways in Axon Regeneration"
9:25 am - 9:35 am
Discussion
9:35 am - 9:45 am
"VPS13A and VPS13C, Proteins Linked to Chorea-Acanthocytosis and Parkinson's, Are Lipid Transporters at Membrane Contact Sites"
9:45 am - 9:50 am
Discussion
9:50 am - 10:15 am
"Disrupted Motor Axonal Development in Motor Neuron Disease"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"Mitochondrial Homeostasis in Parkinsonian Neurodegeneration"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"The Golgi Outpost Protein TPPP Nucleates Microtubules and Is Critical for Myelination"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Inhibition of Mitophagy Through the Loss of Ataxia Gene Vps13D Reveals Novel Neuron-Glia Coordination of Mitochondrial Destruction"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Modeling a Dynamic Axonal ER Network by Hereditary Spastic Paraplegia Proteins"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Keynote Session: From Static Images to Imaging Dynamics in Living Neurons
5:30 pm - 6:15 pm
"The Enigmatic TMEM16 Family"
6:15 pm - 6:30 pm
Discussion
6:30 pm - 7:15 pm
"Spatial and Temporal Dynamics of ER-Organelle Contact Sites in Neurons"
7:15 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure