Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Lysosome Function, Dysfunction and Neurodegenerative Disease
Discussion Leader: Andrea Stavoe (University of Pennsylvania, USA)
3:45 pm - 4:15 pm
Shawn Ferguson (Yale University School of Medicine, USA)
"Lysosome Function, Dysfunction and Neurodegenerative Disease"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Building a Dynamic Neuron: Transport, Translation and Motility
Discussion Leader: Colleen Gillon (University of Toronto, Canada)
7:30 pm - 7:50 pm
Dominique Lessard (University of Vermont, USA)
"Novel Regulation of Kinesin-3 Motility During Axonal Transport by Tau"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Lakshmi Sundararajan (Vanderbilt University, USA)
"Netrin/UNC-6 Triggers Actin Assembly and Non-Muscle Myosin II Activity to Drive Dendrite Retraction in a Self-Avoidance Response"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Yu-Ting Mao (Thomas Jefferson University, USA)
"Filopodia Conduct Target Selection in Cortical Neurons Using Differences in Signal Kinetics of a Single Kinase"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Nicol Birsa (UCL Institute of Neurology, University College London, United Kingdom)
"ALS-Associated FUS Mutant Impairs Protein Translation in Spinal Motor Neurons"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Minding the Gap: Exploring the Uniqueness of Synapses
Discussion Leader: Elizabeth Davenport (University of Edinburgh, United Kingdom)
9:00 am - 9:10 am
Grant Kusick (The Johns Hopkins University School of Medicine, USA)
"Exocytosis Frozen in Time: Synchronous, Asynchronous and Multivesicular Release"
9:10 am - 9:15 am
Discussion
9:15 am - 9:35 am
Vincent Huson (Vrije Universiteit Amsterdam, The Netherlands)
"Overcoming the Barrier: Energetic Contributions of Synaptotagmin-1 to Synaptic Vesicle Fusion"
9:35 am - 9:45 am
Discussion
9:45 am - 9:55 am
Andrea Cuentas-Condori (Vanderbilt University, USA)
"Bulk Endocytosis Removes Presynaptic Terminals in Remodeling GABA Neurons"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
Paul Donlin-Asp (Max Planck Institute for Brain Research, Germany)
"Localization and Dynamics of Translation at the Synapse"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
Mandi Schmidt (University of British Columbia, Canada)
"Death-Associated Protein Kinase 1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Loss in Huntington Disease"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Insider Tips on Publishing in High Impact Journals
Discussion Leader: Erika Holzbaur (University of Pennsylvania, USA)
1:30 pm - 2:00 pm
Moran Furman (Trends in Neurosciences, Cell Press, USA)
"Q&A with an Editor from Trends in Neurosciences "
2:00 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
