Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Routing and Remodeling Membranes at Synapses
Discussion Leader: Christian Hoffmann (German Center for Neurodegenerative Diseases (DZNE), Germany)
3:45 pm - 4:15 pm
Avital Rodal (Brandeis University, United States)
"Routing and Remodeling Membranes at Synapses"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Neuronal Growth, Development and Repair
Discussion Leader: Cathleen Hagemann (Francis Crick, United Kingdom)
7:30 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:05 pm
Christabel Tan (Duke University, United States)
"Ctnnd2 Controls Layer-Specific Astrocyte Morphogenesis by Astrocyte-Neuron Cadherin Interactions Cadherin Interactions"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Andrea Cuentas-Condori (Yale University, United States)
"The Epithelial Na+ Channel, UNC-8, Triggers an Endocytic Mechanism that Recycles Presynaptic Components From Old to New Boutons in Remodeling Neurons"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Anne Quatraccioni (University of Bonn, Germany)
"Regulation of Inhibitory Synaptic Connections and Distal Neuronal Complexity by the Ste20-Like Kinase SLK"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Rajan Thakur (Brown University, United States)
"PDZD8 Promotes Autophagy at ER-Lysosome Contact Sites to Regulate Synaptic Growth"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Irene Dalla Costa (University of South Carolina, United States)
"Acetylation of Axonal G3BP1 Promotes Axon Growth"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Neuronal Plasticity and Function
Discussion Leader: Irene Dalla Costa (University of South Carolina, United States)
9:00 am - 9:20 am
Introduction by Discussion Leader
9:20 am - 9:35 am
Rachel Cain (Thomas Jefferson University, United States)
"Nanoscale Rules governing the Organization of Glutamate Receptors in Spine Synapses are Subunit Specific"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Matthew Koenig (University of Iowa, United States)
"Development of an In-Vitro Model for Axonal Proteostasis"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Cathleen Hagemann (Francis Crick, United Kingdom)
"Going the Distance: Systematically Modelling Axonal Length in Human iPSC-Derived Motor Neurons Using a Bioengineered Platform to Understand Underlying Homeostatic Mechanisms"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Tyler Ogunmowo (The Johns Hopkins University School of Medicine, United States)
"Intersectin Condensates Maintain Replacement Sites for Short Term Plasticity"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Christian Hoffmann (German Center for Neurodegenerative Diseases (DZNE), Germany)
"a-Synuclein Modulates Phase Separation of Presynaptic Condensates"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Panel
Discussion Leader: Rajan Thakur (Brown University, United States)
1:30 pm - 2:30 pm
Panel Discussion
Career Panel: 50/50 Hindsight
Dan Carlin (Alexion, AstraZeneca Rare Disease, United States)
Miriam Leenders (National Institute of Neurological Disorders and Stroke, NIH, United States)
Avital Rodal (Brandeis University, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
