| SATURDAY |
| 1:30 pm - 4:30 pm | Arrival and Check-in |
| 3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:15 pm - 4:00 pm | Cell Junctions and Disease Pathogenesis |
| Discussion Leaders: Carien Niessen (University of Cologne) and Adi Dubash (Northwestern University) |
| 3:15 pm - 3:30 pm | Michelle Rengarajan (Stanford University)
"Rho effectors regulate Listeria monocytogenes invasion in endothelial cells"
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| 3:30 pm - 3:35 pm | Discussion |
| 3:35 pm - 3:50 pm | Vanessa Andries (VIB & Ghent University)
"Role of NANOS family members in tumor progression"
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| 3:50 pm - 4:00 pm | Discussion |
| 4:00 pm - 5:30 pm | Poster Session I |
| 5:30 pm - 7:30 pm | Junction Dynamics |
| Discussion Leaders: Elisabetta Dejana (FIRC Institute for Molecular Oncology) and Chantel Cadwell (Emory University) |
| 5:30 pm - 5:45 pm | Natalie Hudson (University College London)
"Paxillin mediates vascular endothelial cadherin internalization during lymphocyte transmigration"
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| 5:45 pm - 5:50 pm | Discussion |
| 5:50 pm - 6:05 pm | Alejandro Adam (Albany Medical College)
"The many faces of the endothelial adherens junction"
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| 6:05 pm - 6:10 pm | Discussion |
| 6:10 pm - 6:25 pm | Sara Stahley (Emory University)
"Desmosome assembly and disassembly are membrane raft-dependent"
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| 6:25 pm - 6:30 pm | Discussion |
| 6:30 pm - 6:45 pm | Matthias Ruebsam (University of Cologne)
"Classical cadherins control epidermal barrier function: regulation through actomyosin?"
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| 6:45 pm - 6:50 pm | Discussion |
| 6:50 pm - 7:05 pm | Selwin Wu (University of Queensland)
"Cadherin-actomyosin dynamics regulate force at the epithelia adherens junctions"
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| 7:05 pm - 7:10 pm | Discussion |
| 7:10 pm - 7:25 pm | Sabine Fischer (Goethe University)
"Intercellular adhesion determines the formation of three-dimensional cellular spheroids"
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| 7:25 pm - 7:30 pm | Discussion |
| 8:00 pm | Dinner |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 10:20 am | Cytoskeletal Attachments |
| Discussion Leaders: Alpha Yap (University of Queensland) and Koen Tyberghein (VIB & Ghent University) |
| 9:00 am - 9:15 am | Lauren Albrecht (Northwestern University)
"The role of post-translational modification cascades in regulating desmoplakin interactions with intermediate filaments"
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| 9:15 am - 9:20 am | Discussion |
| 9:20 am - 9:35 am | Christopher Wilson (Genentech)
"Rasip1 Regulates Endothelial Junctional Actin Organization and Vascular Stability" |
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 9:55 am | Akila Surendran (National University of Singapore)
"Role of nitric oxide in cytoskeletal regulation during HGF-induced migration of epithelial cells"
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| 9:55 am - 10:00 am | Discussion |
| 10:00 am - 10:15 am | David Escobar (Northwestern University)
"Alpha-catenin-based adhesion relies on a dual-kinase phosphorylation mechanism"
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| 10:15 am - 10:20 am | Discussion |
| 10:20 am - 11:00 am | Career Panel: "Building a global scientific career: making connections and finding your niche" |
|
Panelists:
- Elisabetta Dejana (FIRC Institute for Molecular Oncology)
- Alpha Yap (University of Queensland)
- John Wallingford (University of Texas at Austin)
- Carien Niessen (University of Cologne)
|
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Tissue Patterning and Development |
| Discussion Leaders: John Wallingford (University of Texas at Austin) and Abbye McEwen (Northwestern University) |
| 1:30 pm - 1:45 pm | Shuichi Hayashi (Riken Center for Developmental Biology)
"Protocadherin-17 sustains amygdala axon extension by contact-dependent mechanisms"
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| 1:45 pm - 1:50 pm | Discussion |
| 1:50 pm - 2:05 pm | Tom Van Nieuwenhuysen (Ghent University)
"Embryonic wound healing requires activation of junctional actomyosin contractility by the catenin p0071"
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| 2:05 pm - 2:10 pm | Discussion |
| 2:10 pm - 2:25 pm | George Eisenhoffer (University of Utah)
"Desmoplakin buffers epithelia against mechanical tension during development to prevent cell shedding"
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| 2:25 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
