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Cell Contact and Adhesion (GRS)

Gordon Research Seminar

Regulation of Molecular and Mechanical Signaling by Cellular Adhesions

June 24 - 25, 2023
Chairs Gabriel Muhire Gihana and Lotte van den Goor
Colby-Sawyer College
541 Main Street
New London, New Hampshire, United States
 Venue and Travel Information

Conference Description

The Cell Contact and Adhesion GRS provides a unique forum for young doctoral and post-doctoral researchers to present their work, discuss new methods, cutting edge ideas, and pre-published data, as well as to build collaborative relationships with their peers. Experienced mentors and trainee moderators will facilitate active participation in scientific discussion to allow all attendees to be engaged participants rather than spectators.

The 2023 Cell Contact and Adhesion Gordon Research Seminar will feature trainee scientists who are unraveling the biology of cellular attachments. Particular attention will be paid to the studies investigating how cellular adhesions regulate molecular and mechanical signals within cells and tissues.

Related Meeting

This GRS will be held in conjunction with the "Cell Contact and Adhesion" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Phase Separation Promotes Integrin Receptor Clustering and Downstream Signaling
Discussion Leader: Tadamoto Isogai (UT Southwestern Medical Center, United States)
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:20 pm
Lindsay Case (MIT, United States)
"Phase Separation Promotes Integrin Receptor Clustering and Downstream Signaling"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Basic Biology of Cell Contacts and Adhesions
Discussion Leader: Claira Sohn (UT Health San Antonio, United States)
7:30 pm - 7:45 pm
Zie Craig (University of Michigan, United States)
"Anillin Regulates Rho Activity during Cell-Cell Junction Remodeling"
7:45 pm - 7:55 pm
Discussion
7:55 pm - 8:10 pm
Tanmay Sadhanasatish (University of Muenster, Germany)
"A Molecular Optomechanics Approach to Reveal Functional Relevance of Force-Bearing Cellular Linkages"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
Rozemarijn van der Veen (Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Germany)
"Nanoscale Insight into the Role of Occludin in Tight Junction Architecture"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:00 pm
Hanyin Zhang (CECAD, Germany)
"Epithelial Actomyosin State Determines How Adherens Junctions Promote Desmosome Assembly"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Cecilia Arriagada (Rutgers University, United States)
"Role of Mesodermal Fibronectin in Mechanotransduction During Cardiac Development"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Cell Attachments in Disease and Beyond
Discussion Leader: Navaneetha Krishnan Bharathan (The Pennsylvania State University, United States)
9:00 am - 9:15 am
Sayantika Ghosh (University of Warwick, United Kingdom)
"Study of Cell-Cell Adhesion Formation and Dynamics in Cancer Cells Using a Hybrid Cell - Lipid Bilayer System"
9:15 am - 9:25 am
Discussion
9:25 am - 9:40 am
Ludovico Maggi (Biozentrum, University of Basel (CH), Switzerland)
"Dynamic Regulation of Actomyosin Tension within Junction-based Lamellipodia (JBL) Drives Endothelial Cell Rearrangements during Blood Vessel Morphogenesis"
9:40 am - 9:50 am
Discussion
9:50 am - 10:05 am
Junior West (Johns Hopkins University School of Medicine, United States)
"The Tight Junction Inhibits Cancer Invasion and Metastasis"
10:05 am - 10:15 am
Discussion
10:15 am - 10:30 am
Coryn Hoffman (Penn State College of Medicine, United States)
"A Novel Role for the Endoplasmic Reticulum (ER) as a Cell Adhesion Stress Sensor"
10:30 am - 10:40 am
Discussion
10:40 am - 10:55 am
Aurore Maciejewski (INSERM DRPA11, France)
"Roles of Vinculin at Intercellular Junctions in Collective Amoeboid Migration of Colorectal Cancer Clusters"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: What's my PhD Worth? Career Opportunities After Your PhD/Postdoc
Discussion Leader: Abbey Perl (Northwestern University, United States)
1:30 pm - 2:30 pm
Panel Discussion
What's my PhD Worth? Career Opportunities After Your PhD/Postdoc
  • Timothy Fessenden (Journal of Cell Biology, United States)
  • Lindsay Case (MIT, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes

Contributors

National Institutes of Health (NIH)
Gene Tools, LLC
United Therapeutics Corporation

Research reported in this publication was supported by the National Cancer Institute of the National Institutes of Health under Award Number R13CA281325. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Conference Links

Conference History Cell Contact and Adhesion
Additional Fee Info

Cell Contact and Adhesion
June 8 - 13, 2025


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