Conference Description
The Cell Death community is thrilled to participate in the GRC Connects 2.0 pilot program in 2024. GRC Connects 2.0 matches a long-time attendee
at a Gordon Research Conference with a first-time attendee to ensure new attendees feel welcomed and included as a member of the community.
Mentors and mentees will be invited to meet at a reception from 5:00 p.m.- 6:00 p.m. on Sunday immediately prior to dinner and the Sunday
evening session. Funding has been generously provided by the Gordon and Betty Moore Foundation for the 2024 pilot program. If you are
interested in participating, please contact connects@grc.org. Space is limited and available on a first come, first serve basis.
The Cell Death GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.
Cell death and inflammation are closely linked arms of the innate immune response to combat infection and tissue malfunction. While the ability to sense danger is central to any organism’s strategy for maintaining tissue function, uncontrolled or excessive inflammatory responses can cause tissue damage and contribute to the pathogenesis of chronic inflammatory diseases, including psoriasis, neurodegenerative diseases, inflammatory bowel disease and asthma. Further, tumor cells frequently evade immune detection and elimination by suppressing cell death and innate immune responses. Recent advancements in our understanding of the intricate signals originating from dying cells have revealed that cell death serves as more than just an endpoint. It facilitates the exchange of information between the dying cell and cells of the tissue micro-environment, particularly immune cells, alerting and recruiting them to the site of disturbance. However, not all deaths are suspicious. While different types of cell deaths contribute to tissue homeostasis and defence against pathogens, dysfunctional or mis-timed cell death can lead to developmental abnormalities, immune deficiencies, inflammatory conditions, and cancer. At this conference, we will examine the molecular mechanisms that regulate various cell death processes and how this knowledge can be harnessed to treat immunological disorders, neurodegenerative disease, infections, and cancer.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by March 30, 2024. Please check back for updates.
Keynote Session: Perspectives on the Mechanism and Function of Cell Death in Health and Disease
Discussion Leaders
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Ana Garcia-Saez (University of Cologne, Germany)
Speakers
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Manolis Pasparakis (University of Cologne, Germany)
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Francis Chan (Liangzhu Laboratory, Zhejiang University, China)
Fundamental Mechanisms of Cell Death
Discussion Leaders
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Lynn Wong (University of Zurich, Switzerland)
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Douglas Green (St. Jude Children's Research Hospital, United States)
Speakers
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Kim Newton (Genentech, United States)
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John Silke (Walter and Eliza Hall Institute of Medical Research, Australia)
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Junying Yuan (Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, China)
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Michelle Kelliher (UMass Chan Medical School, United States)
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Mathieu Bertrand (Ghent University, Belgium)
Innate Immune Sensing and Cell Death
Discussion Leaders
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Katia Cosentino (University of Osnabrück, Germany)
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Andrew Oberst (University of Washington, United States)
Speakers
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Kate Schroder (The University of Queensland, Australia)
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Kate Fitzgerald (Umass Chan Medical School, United States)
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Veit Hornung (Ludwig-Maximilians-Universität Munich, Germany)
Regulation of Lytic Forms of Cell Death
Discussion Leaders
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Henning Walczak (University of Cologne, Germany / University College London, United Kingdom)
Speakers
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James Murphy (Walter and Eliza Hall Institute of Medical Research, Australia)
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Katia Cosentino (University of Osnabrück, Germany)
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Domagoj Vucic (Genentech, United States)
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Feng Shao (National Institute of Biological Sciences, Beijing, China)
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Monica Yabal (Technical University of Munich, Germany)
Inflammation and Cell Death
Discussion Leaders
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John Silke (Walter and Eliza Hall Institute of Medical Research, Australia)
Speakers
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Hamid Kashkar (University of Cologne, Germany, Germany)
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Lynn Wong (University of Zurich, Switzerland)
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Kevin Ryan (Cancer Research UK Beatson Institute, United Kingdom)
Cell Death Signalling Platforms
Discussion Leaders
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Kevin Ryan (Cancer Research UK Beatson Institute, United Kingdom)
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Kim Newton (Genentech, United States)
Speakers
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Marion MacFarlane (MRC Toxicology Unit, University of Cambridge, United Kingdom)
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Henning Walczak (University of Cologne, Germany / University College London, United Kingdom)
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Tiffany Reese (University of Texas Southwestern Medical Center, United States)
Non-Canonical Forms of Cell Death
Discussion Leaders
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Michelle Kelliher (UMass Chan Medical School, United States)
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Mathieu Bertrand (Ghent University, Belgium)
Speakers
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Marcus Conrad (Helmholtz Zentrum Munich, Germany)
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Silvia von Karstedt (University of Cologne, Germany)
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Eric Baehrecke (University of Massachusetts Chan Medical School, United States)
Cancer and the Immune System
Discussion Leaders
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Silvia von Karstedt (University of Cologne, Germany)
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Hamid Kashkar (University of Cologne, Germany, Germany)
Speakers
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Andreas Strasser (Walter and Eliza Hall Institute of Medical Research, Australia)
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Stephen Tait (Cancer Research UK Scotland Institute, United Kingdom)
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Anthony Letai (Dana-Farber Cancer Institute, United States)
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Judy Lieberman (Boston Children's Hospital, Harvard Medical School, United States)
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Jannie Borst (Leiden University Medical Center, The Netherlands)
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Gemma Kelly (Walter and Eliza Hall Institute of Medical Research, Australia)
Inflammation and Tissue Homeostasis
Discussion Leaders
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James Murphy (Walter and Eliza Hall Institute of Medical Research, Australia)
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Marion MacFarlane (MRC Toxicology Unit, University of Cambridge, United Kingdom)
Speakers
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Theresa Pizarro (Case Western Reserve University School of Medicine, United States)
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Andrew Oberst (University of Washington, United States)
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Douglas Green (St. Jude Children's Research Hospital, United States)
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LORENZO GALLUZZI (Weill Cornell Medicine, United States)
The GRC Power Hour™
Organizers
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Monica Yabal (Technical University of Munich, Germany)
