Saturday |
2:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | Keynote Session: Mechanisms of Cell Shape Change In Vivo |
| Discussion Leader: Elaine Fuchs (The Rockefeller University, USA) |
3:45 pm - 4:25 pm | Bob Goldstein (University of North Carolina at Chapel Hill, USA) "Mechanisms of Cell Shape Change In Vivo" |
4:25 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Measuring Cell Polarity – Analytical Imaging Tools and Modelling |
| Discussion Leader: Daniel Lew (Duke University Medical Center, USA) |
7:30 pm - 7:45 pm | Aaron Mertz (Rockefeller University, USA) "How Is a Stratified Epithelium Built Mechanically In Vivo?" |
7:45 pm - 7:50 pm | Discussion |
7:50 pm - 8:05 pm | Abhijit Deb Roy (University of Connecticut Health Center, USA) "An Optogenetic Approach to Delineate Spatial Regulation of Semaphorin-Plexin Signaling in Contact Inhibition of Locomotion" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:25 pm | Floris Bosveld (Institut Curie, France) "Spindle Orientation in Epithelial Tissue" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:45 pm | Teresa Zulueta-Coarasa (University of Toronto, Canada) "Dynamic, Stochastic Actomyosin Pulses Promote Collective Cell Migration and Rapid Embryonic Wound Repair" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:05 pm | Olga Loza (Tel Aviv University, Israel) "A Synthetic Biology Approach for Studying Fat4-Ds1 Planar Cell Polarity Signaling" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Allyson Sgro (Princeton University, USA) "From Intracellular Signaling to Collective Behavior: Understanding the Dynamical Origins of Collective cAMP Oscillations in Dictyostelium discoideum" |
9:25 pm - 9:30 pm | Discussion |
Sunday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Polarity in Cell Migration and Disease |
| Discussion Leader: Luke McCaffrey (McGill University, Canada) |
9:00 am - 9:15 am | Danielle Park (Francis Crick Institute, United Kingdom) "Extracellular Matrix Anisotropy in Cancer Invasion and Metastasis" |
9:15 am - 9:20 am | Discussion |
9:20 am - 9:35 am | Yuliya Petrova (University of Virginia, USA) "Roles of E-Cadherin Mutations and Adhesion Activity in Cancer" |
9:35 am - 9:40 am | Discussion |
9:40 am - 9:55 am | Mukhtar Ahmed (Vanderbilt University, USA) "The Par3-Exocyst Interaction Is Central for Mammary Epithelial Cell Survival" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:15 am | Vanesa Jimenez-Amilburu (Max Planck Institute for Heart and Lung Research, Germany) "Cardiomyocyte Polarity Dynamics During Heart Trabeculation" |
10:15 am - 10:20 am | Discussion |
10:20 am - 10:35 am | Manuel Hotz (Stanford University, USA) "Pumilio-Dependent Transcript Asymmetry Drives Polarization of Chemotactic Cells" |
10:35 am - 10:40 am | Discussion |
10:40 am - 10:55 am | Paulina Mrozowska (Tohoku University, Japan) "Regulation of Podocalyxin Trafficking by Rab Small GTPases in 2D and 3D Epithelial Cell Cultures" |
10:55 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Polarity in Morphogenesis and Signal Transduction |
| Discussion Leader: Jody Rosenblatt (Huntsman Cancer Institute, University of Utah, USA) |
1:30 pm - 1:45 pm | Andrea Dimitracopoulos (MRC Laboratory for Molecular Cell Biology, University College London, United Kingdom) "The Role of Mitotic Rounding in Spindle Positioning" |
1:45 pm - 1:50 pm | Discussion |
1:50 pm - 2:05 pm | Mitchell Butler (The University of Texas at Austin, USA) "The Control of Planar Cell Polarity Patterning Dynamics During Vertebrate Development" |
2:05 pm - 2:10 pm | Discussion |
2:10 pm - 2:25 pm | Matias Escobar (University of Pennsylvania, USA) "Dissecting Microtubule-Actin Crosslinking Factor (Macf1) Function in Establishing Oocyte Polarity and Nuclear Positioning" |
2:25 pm - 2:30 pm | Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |