Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Fungal Hijacking and Host Manipulation
Discussion Leader: João Araújo (The New York Botanical Garden, United States)
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:05 pm
Matthew Kasson (West Virginia University, United States)
"Exploring the Genetic Underpinnings of Secondary Metabolite Production in the Cicada Pathogen Massospora cicadina "
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:30 pm
Sam Edwards (University of Copenhagen, Denmark)
"Zombie Flies: Behavioral Manipulation by an Insect-Destroying Fungus"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:55 pm
Pietro Spanu (Imperial College London, United Kingdom)
"Cross-Kingdom smallRNA Signalling: New Insights into the Complex Cross-Talk in Cereal Powdery Mildews"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
Elizabeth Ballou (University of Exeter , United Kingdom)
"How do Bacteria Influence Fungal Responses to Stress?"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Cellular Organization and Molecular Biology
Discussion Leader: James Kronstad (University of British Columbia, Canada)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:25 am
Joshua Nosanchuk (Albert Einstein College of Medicine, United States)
"What Candida Extracellular Vesicles Teach Us"
9:25 am - 9:35 am
Discussion
9:35 am - 9:50 am
Duncan Wilson (University of Exeter, United Kingdom)
"From Ions to Biomes: How Micronutrient Scavenging Shapes Environmental Adaptation"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
Lillian Fritz-Laylin (University of Massachusetts, United States)
"Chytrid Fungi and the Functional Specification of Actin Networks"
10:15 am - 10:25 am
Discussion
10:25 am - 10:50 am
Coffee Break
10:50 am - 11:05 am
Robert Arkowitz (University of Côte d'Azur, France)
"Fungal Invasion - Growing Against a Resistive Force"
11:05 am - 11:15 am
Discussion
11:15 am - 11:30 am
Richard Wilson (University of Nebraska-Lincoln, United States)
"tRNA Modification and Codon Usage Tune Magnaporthe oryzae Effector Secretion in Living Host Rice Cells"
11:30 am - 11:40 am
Discussion
11:40 am - 11:55 am
Jenna Christensen (University of California, San Diego, United States)
"Uncovering Design Principles of Intracellular Transport Using Fungal Comparative Biology"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:20 pm
Marisela Garduño-Rosales (CICESE, Mexico)
"From Cap to Collar: Ontogeny of the Endocytic Collar in Neurospora crassa "
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Elaine Bignell (The University of Exeter, United Kingdom) and Christina Cuomo (Broad Institute of MIT and Harvard, United States)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Fungal Mutualism and Symbiotic Interactions
Discussion Leader: Christine Voisey (AgResearch, New Zealand)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 7:55 pm
Gregory Bonito (Michigan State University, United States)
"The Mortierella Microbiome: Symbiosis with Bacteria and Photobionts"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:20 pm
Anna Rosling (Uppsala University, Sweden)
"Genomic Signatures Linked to the Obligate Symbiotic Lifestyle of Arbuscular Mycorrhizal Fungi"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Gabriel Giger (Eidgenössische Technische Hochschule Zürich, Switzerland)
"Expanding the Host Range for a Fungal Endosymbiont Through Implantation by FluidFM"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:05 pm
General Discussion
9:05 pm - 9:20 pm
Neftaly Cruz Mireles (The Sainsbury Laboratory, United Kingdom)
"Phosphoproteomic Analysis"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Genomic Perspectives on Fungal Evolution
Discussion Leader: Christina Cuomo (Broad Institute of MIT and Harvard, United States)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:25 am
David Hibbett (Clark University, United States)
"O Shiitake Mushrooms! Phylogenomics and Evolution of the Genus Lentinula Above and Below the Species Level"
9:25 am - 9:35 am
Discussion
9:35 am - 9:50 am
Daniel Croll (University of Neuchatel, Switzerland)
"Evolving Fungal Genomes: How Plasticity Fuels Adaptation in Plant Pathogens"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
Bridget Barker (Northern Arizona University, United States)
"Dust Devil or Fantastic Yeast? The Mysterious Life of Coccidioides"
10:15 am - 10:25 am
Discussion
10:25 am - 10:50 am
Coffee Break
10:50 am - 11:05 am
Emile Gluck-Thaler (University of Neuchatel, Switzerland)
"Giant Starship Elements Mobilize Accessory Genes in Fungal Genomes"
11:05 am - 11:15 am
Discussion
11:15 am - 11:30 am
Hung-Ji Tsai (University of Birmingham, United Kingdom)
"Pleiotropic Effects of Aneuploidy in Stress Adaptation"
11:30 am - 11:40 am
Discussion
11:40 am - 11:55 am
Antonis Rokas (Vanderbilt University, United States)
"Evolving Moldy Murderers: Aspergillus as a Model for Studying the Repeated Evolution of Opportunistic Pathogenicity"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:20 pm
Lori Huberman (Cornell University, United States)
"Investigating Fungicide Mode of Action Using Massively Parallel Screens"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Fungi in the Microbiome and Complex Communities
Discussion Leader: Gregory Bonito (Michigan State University, United States)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 7:55 pm
Nina Gunde-Cimerman (University of Ljubljana, Slovenia)
"Surprising Fungal Life on Greenland Ice Sheet"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:20 pm
Iliyan Iliev (Weill Cornell Medicine, United States)
"Functional Mycobiota Exploration: Mechanisms of Mucosal Immunity Regulation and Beyond"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Teresa Pawlowska (Cornell University, United States)
"Unraveling the Mechanisms of Symbiosis Formation Between Early-divergent Fungi and Bacteria"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:10 pm
Michelle Afkhami (University of Miami, United States)
"Environmental Stress Destabilizes Microbial Networks"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Fungal Virulence and Drug Resistance
Discussion Leader: Elaine Bignell (The University of Exeter, United Kingdom)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:25 am
Antonio Di Pietro (Universidad de Córdoba, Spain)
"Host Adaptation in the Trans-kingdom Pathogen Fusarium oxysporum "
9:25 am - 9:35 am
Discussion
9:35 am - 9:50 am
Tamara Doering (Washington University Medical School, United States)
"Naturally Occurring Genome Variants that Influence Cryptococcal Virulence"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
Jeniel Nett (University of Wisconsin-Madison, United States)
"Neutrophil-Candida auris Interactions: Focus on the Cell Wall"
10:15 am - 10:25 am
Discussion
10:25 am - 10:50 am
Coffee Break
10:50 am - 11:05 am
Jessica Brown (University of Utah, United States)
"Exploiting Synergistic and Antagonistic Interactions Between Drugs to Improve Treatment of Systemic Fungal Infections"
11:05 am - 11:15 am
Discussion
11:15 am - 11:30 am
Carol Munro (University of Aberdeen, United Kingdom)
"Targeting the Fungal Cell Wall"
11:30 am - 11:40 am
Discussion
11:40 am - 11:55 am
Mike Bromley (University of Manchester, United Kingdom)
"The COFUN Project: Competitive Fitness Profiling Reveals Insights into Mechanisms of Drug Resistance and Virulence in A. fumigatus "
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:20 pm
Iuliana Ene (Institut Pasteur, France)
"Mapping Genome Evolution Towards Increased Azole Resistance"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
7:30 pm - 9:30 pm
Fungi as Bioresources
Discussion Leader: Nancy Keller (University of Wisconsin-Madison, United States)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 7:55 pm
Jason Slot (The Ohio State University, United States)
"Breaking Out of the Mold: Evolutionary Considerations for Prospecting in Genomes"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:20 pm
Isabelle Benoit Gelber (Concordia University, Canada)
"Biosynthetic Gene Clusters in Aspergillus niger : Insights into Structure and Regulation"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Sarah Beattie (University of Iowa, United States)
"Look into the Light: A Luciferase-Based Assay for the Identification of Novel, Mold-Active Antifungals"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:10 pm
Joseph Spraker (Hexagon Bio, Inc, United States)
"Merging Computational and Synthetic Biology for the Discovery of Bioactive Fungal Natural Products"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Sensing, Signaling and Development
Discussion Leader: Alexander Idnurm (University of Melbourne, Australia)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:25 am
Yi Liu (University of Texas Southwestern Medical Center, United States)
"Synonymous but not Silent, Codon Usage Regulates Gene Expression and Protein Structure"
9:25 am - 9:35 am
Discussion
9:35 am - 9:50 am
Shay Covo (Hebrew University of Jerusalem, Israel)
"UV Response of Fusarium Species"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
Janet Quinn (Newcastle University, United Kingdom)
"Fungal Stress-Signalling Pathways as Mediators of Virulence (and How We can Exploit This)"
10:15 am - 10:25 am
Discussion
10:25 am - 10:50 am
Coffee Break
10:50 am - 11:05 am
Neil Brown (University of Bath, United Kingdom)
"Host Nutrient Sensing: Drivers of Fungal Development and Disease"
11:05 am - 11:15 am
Discussion
11:15 am - 11:30 am
Daniel Kornitzer (Technion - Israel Institute of Technology, Israel)
"Sensing, Response and Utilization of Different Iron Sources"
11:30 am - 11:40 am
Discussion
11:40 am - 11:55 am
Lauren Ryder (The Sainsbury Laboratory, United Kingdom)
"A Sensor Kinase Controls Turgor-driven Plant Cell Invasion by the Rice Blast Fungus Magnaporthe oryzae "
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:20 pm
Julia Schumacher (Bundesanstalt für Materialforschung und -prüfung (BAM), Germany)
"Fungi in Extreme Habitats: Lessons from the Microcolonial Black Fungus Knufia petricola "
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Late-Breaking Topics
Discussion Leaders: Nick Talbot (The Sainsbury Laboratory, United Kingdom) and Anna Selmecki (University of Minnesota Medical School, United States)
7:30 pm - 7:40 pm
Ana Rodríguez-López (University of Córdoba, Spain)
"Monitoring Transposon Dynamics in the Genome of the Phytopathogenic Fungus Fusarium oxysporum "
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
David Diaz Escandon (University of Alberta, Canada)
"An Overlooked Symbiotic Clade in Ascomycota"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Kristyn Robinson (University of Massachusetts Amherst, United States)
"Amphibian Mucus Triggers a Developmental Transition in the Frog-Killing Chytrid Fungus"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Rina Zuchman (Technion, Israel)
"Phosphorylation/Dephosphorylation of the Cochliobolus heterostrophus Stress-Activated MAPK Hog1 in Response to Plant Phenolic Acids"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Zoë Hilbert (University of Utah, United States)
"Training a Pathogen: Uncovering the Evolutionary Mechanisms of Host Adaptation in a Human Fungal Pathogen"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Charles Puerner (Dartmouth College, Geisel School of Medicine, United States)
"Unique and Conserved Responses to Oxygen Availability in Aspergillus fumigatus Isolates Reveals Biofilm Population Heterogeneity"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Corey Frazer (Brown University, United States)
"Candida albicans Cell Fate is Determined by Transcription Factor Condensates Acting at Super-Enhancer-Like Elements"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Abigail LaBella (Vanderbilt University, United States)
"Synonymous Codon Usage as a Lens into the Metabolic Ecology of Budding Yeasts"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure