Session 1.
(Sunday eve) |
Cellulose - The substrate |
| Discussion Leader: Henri Chanzy (France) |
| 7:00 - 7:30 |
Wilson & Bayer
Welcome |
| 7:30 - 7:45 |
Henri Chanzy
Overview |
| 7:45 - 8:15 |
Rajai Atalla (USA)
The complexity of the world of cellulose |
| 8:15 - 8:30 |
Breather |
| 8:30 - 9:00 |
Junji Sugiyama (Japan)
Aspects of native cellulose microfibril at molecular dimension |
| 9:00 - 9:30 |
Paul Langan (USA)
Recent insight into the molecular description of cellulose crystals |
| 9:30 - 10:0 |
Claire Boisset (France) *
Hydrolysis of cellulose substrates by cellulases and cellulosomes |
| From 10:00 |
General Discussion |
|
* Featured Young Scientist's Talk |
| Session 2. (Monday morn) |
Free cellulases versus cellulosomes |
| Discussion Leader: Göran Pettersson (Sweden) |
| 9:00 - 9:15 |
Göran Pettersson
Opening Remarks |
| 9:15 - 9:45 |
Tuula Teeri (Sweden)
Trichoderma reesei: Free cellulase systems in fungi |
| 9:45 - 10:15 |
Neil Gilkes (Canada)
Cellulomonas fimi: Free cellulase systems in bacteria |
| 10:15 - 10:30 |
General Discussion |
| 10:30 - 10:45 |
Coffee Break |
| 10:45 - 11:15 |
Pierre Béguin (France)
Clostridium thermocellum: Cellulosome complexes in bacteria |
| 11:15 - 11:45 |
Oded Shoseyov (Israel)
Why plant cellulases lack CBDs |
| 11:45 - 12:15 |
Rustem Aminov (USA)
The genomes of cellulolytic rumen bacteria |
| 12:15 - 12:30 |
General Discussion |
| 12:30 |
Lunch |
| Afternoon |
Discussions and Poster Sessions |
| 6:00 |
Dinner |
| Session 3. (Monday eve) |
The modular structure of cellulases and cellulosomes |
| Discussion Leader: Roy Doi (USA) |
| 7:30 - 7:45 |
Roy Doi
Opening Remarks |
| 7:45 - 8:15 |
Gideon Davies (England)
Family Planning: Specificity and mechanism of glycoside hydrolases |
| 8:15 - 8:45 |
Harry Gilbert (England)
Structures of accessory domains |
| 8:45 - 9:15 |
Doug Kilburn (Canada)
Families of cellulose-binding domains CBDs |
| 9:15 - 9:45 |
David Wu (USA)
The cohesin-dockerin interaction |
| 9:45 - 10:00 |
General Discussion |
| Session 4. (Tuesday morn) |
Structure of catalytic modules |
| Discussion Leaders: T. Alwyn Jones (Sweden) and Richard Haser (France) |
| 9:00 - 9:45 |
Alwyn Jones and Jerry Ståhlberg (Sweden)
Crystal structures of cellulases from Trichoderma reesei |
| 9:45 - 10:15 |
Pedro Alzari (France)
Structure and mechanism of cellulosomal glycosidases from C. thermocellum |
| 10:15 - 10:30 |
Breather |
| 10:30 - 10:45 |
Richard Haser (France)
Structures of cellulosomal cellulases from C. cellulolyticum |
| 10:45 - 11:15 |
Goetz Parsiegla (France)
The 3D structure and mechanism of action of a Family-48 catalytic module |
| 11:15 - 11:45 |
David Rose (Canada)
Probing the catalytic mechanism of ß-glycosidases through structural studies of covalent intermediates |
| 11:45 - 12:15 |
John Brady (USA)
Molecular mechanics studies of cellulases |
| 12:15 - 12:30 |
General Discussion |
| 12:30 |
Lunch |
| Afternoon |
Discussions and Poster Sessions |
| Session 5. (Tuesday eve) |
Mechanisms of cellulase action |
| Discussion Leaders: Marc Claeyssens (Belgium) and Hugues Driguez (France) |
| 7:30 - 8:00 |
Marc Claeyssens & Hugues Driguez
Opening Remarks |
| 8:00 - 8:30 |
Dave Zechel (Canada)
On the catalytic mechanisms of the glycosyl hydrolases |
| 8:30 - 9:00 |
Michael L. Sinnott (England)
Kinetic probes of cellulase action |
| 9:00 - 9:30 |
Larry P. Walker (USA)
Bridging the gap from molecular mechanisms to heterogeneous reactions |
| 9:30 - 9:45 |
Brian Barr *
Binding of oligosaccharides |
| 9:45 - 10:00 |
General Discussion |
|
* Featured Young Scientist's Talk |
| Session 6. (Wednesday morn) |
Structures and functions of accessory modules |
| Discussion Leader: Anthony J. Clarke (Canada) |
| 9:00 - 9:15 |
Anthony J. Clarke
Opening Remarks |
| 9:15 - 9:45 |
Markus Linder (Finland)
Family -I CBD and mutants |
| 9:45 - 10:15 |
Lawrence McIntosh (Canada)
Solution structures of CBDs |
| 10:15 - 10:30 |
General Discussion |
| 10:30 - 10:45 |
Breather |
| 10:45 - 11:15 |
Yuval Shoham (Israel)
Crystal structures of scaffoldin domains |
| 11:15 - 11:45 |
Joshua Sakon (USA)
Structure and function of Family-IIIc CBD |
| 11:45 - 12:15 |
Henri-Pierre Fierobe (France) *
The relationship between structure and function of the dockerin domain |
| 12:15 - 12:30 |
General Discussion |
| 12:30 |
Lunch |
| Special Session (Wednesday afternoon) |
Cellulases and their components in industry |
| Discussion Leader: M. Bhat (England) |
| 3:00 - 3:30 |
M. Bhat
Opening Remarks |
| 3:30 - 4:00 |
Martin Schülein (Denmark)
Properties and applications of the Humicola cellulases |
| 4:00 - 4:30 |
Theresa C. White (Canada)
The role of Trichoderma cellulase catalytic and binding domains in enzymatic cellulose hydrolysis for biomass conversion |
| 4:30 - 5:00 |
Pennina Safer (Israel)
Emerging platforms in CBD-based biotechnology |
| 5:00 - 5:30 |
General Discussion |
| 6:00 |
Dinner |
| Session 7. (Wednesday eve) |
Applications of cellulases, cellulosomes and their components |
| Discussion Leaders: Mike Penner (USA) and M. Bhat (England) |
| 7:30 - 8:00 |
Mike Penner |
| 8:00 - 8:30 |
Mike Himmel (USA)
Improved cellulases for bioethanol production |
| 8:30 - 9:00 |
Jack Saddler (Canada)
Use of cellulases to modify fiber characteristics in Kraft, mechanical and dissolving pulps |
| 9:00 - 9:30 |
Itai Ben-Har (Israel) *
Applications of CBD in antibody engineering |
| 9:30 - 10:00 |
General Discussion |
|
* Featured Young Scientist's Talk |
| Session 8. (Thursday morn) |
Microbial cellulase systems
- Free cellulases and/or cellulosomes? |
| Discussion Leaders: Jean-Pierre Belaich (France) and L. Ljungdahl (USA) |
| 9:00 - 9:15 |
Diana Irwin (USA)
The cellulase system of Thermomonospora fusca |
| 9:15 - 9:30 |
Frederic Barras (France)
The cellulase system of Erwinia |
| 9:30 - 9:45 |
Cecil Forsberg (Canada)
The cellulase system of Fibrobacter succinogenes |
| 9:45 - 10:00 |
Hildgund Schrempf (Germany)
The cellulase system of Streptomyces |
| 10:00 - 10:15 |
Breather |
| 10:15 - 10:30 |
Jean-Pierre Belaich (France)
The cellulosome of Clostridium cellulolyticum |
| 10:30 - 10:45 |
Kazuo Sakka (Japan)
The cellulosome of Clostridium josui |
| 10:45 - 11:00 |
Susan Leschine (USA)
The cellulosome of Clostridium papyrosolvens |
| 11:00 - 11:15 |
Shiyou Ding (Israel)
Cellulosomes in Acetivibrio cellulolyticus and Bacteroides cellulosolvens |
| 11:15 - 11:30 |
Harry Flint (Scotland)
Cellulosomes in Ruminococcus flavefaciens |
| 11:30 - 11:45 |
Kunio Omiya (Japan)
Cellulosomes in Ruminococcus albus |
| 11:45 - 12:00 |
Lars Ljungdahl (USA)
The cellulosome of the polycentric, anaerobic fungus Orpinomyces |
| 12:00 - 12:30 |
General Discussion |
| 12:30 |
Lunch |
| Afternoon |
Discussions and Poster Sessions |
| 6:00 |
GRC Banquet |
| Session 9. (Thursday eve) |
After banquet speeches |
|
David Wilson and Ed Bayer
Introductory Remarks |
|
Doug Eveleigh (USA)
Microbial Mining of Manure - Cellulase |
|
Pierre Beguin (France)
Cellulases : What you find is more fun than what you look for |
