SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:45 pm | Welcome / Introductory Comments by GRC Site Staff, Chair and Vice-Chair |
7:45 pm - 9:30 pm | SETTING THE STAGE, MATCHING ENZYME AND SUBSTRATE |
| Discussion Leader: Edward Bayer (Weitzmann Institute, Israel) |
7:45 pm - 8:15 pm | Michael Himmel (DOE-NREL, USA) "Understanding Plant Cell Walls: Towards Improved Biomass Conversion and New Materials" |
8:15 pm - 8:25 pm | Discussion |
8:25 pm - 8:55 pm | Alisdair Boraston (University of Victoria, Canada) "Protein-carbohydrate recognition" |
8:55 pm - 9:05 pm | Discussion |
9:05 pm - 9:30 pm | General Discussion |
9:30 pm | Additional Discussions at Proctor Academy Clubhouse |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | CELL WALL ARCHITECTURE AND DISPLAY |
| Discussion Leader: Udaya C. Kalluri (DOE-ONL, USA) |
9:00 am - 9:25 am | Vincent Bulone (KTH, Seden) "Cellulose biosynthesis" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Claire Halpin (University of Dundee, UK) "Lignin biosynthesis and manipulation" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:35 am | Coffee Break |
10:35 am - 11:00 am | Debra Mohnen (UGA, USA) "Understand the laying down of the complete plant cell wall" |
11:00 am - 11:10 am | Discussion |
11:10 am - 11:35 am | Paul Knox (University of Leeds UK) "The use of molecular probes to generate an integrated view of polysaccharides and plant cell wall structures" |
11:35 am - 11:45 am | Discussion |
11:45 am - 12:10 pm | Paul Dupree (University of Cambridge, UK) "Profiling plant cell wall polysaccharide quantity and structures with
hydrolases" |
12:10 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | PLANT CELL WALL HYDROLASE STRUCTURE AND FUNCTION - CELLULOSOMAL MODULE INTERACTIONS |
| Discussion Leader: Stephen Smith (Queens University, Canada) |
7:30 pm - 8:00 pm | Henri-Pierre Fierobe (CNRS, Marseille, France) "Cellulosome chimeras displaying novel characteristics" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Ilit Noach (Weizmann Institute, Israel) "Cellulosome diversity, flexibility and modular arrangement revealed from cohesin structural studies" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Michael Crowley ((DOE-NREL, USA) "From Dissecting to Building the Cellulosome: Structural Studies of Multi-Modular Complexes" |
9:20 pm - 9:30 pm | Discussion |
9:30 pm | Additional Discussions at Proctor Academy Clubhouse |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 10:05 am | PLANT CELL WALL HYDROLASE STRUCTURE AND FUNCTION - CELLULOSOMAL MODULE INTERACTIONS (CONTINUED) |
| Discussion Leader: Stephen Smith (Queens University, Canada) |
9:00 am - 9:30 am | Elizabeth Ficko-Blean (University of Victoria, Canada) "Portrait of an enzyme: a complete structural analysis of a multi-modular beta-N-acetylglucosaminidase from Clostridium perfringens" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:05 am | General Discussion |
10:05 am - 12:30 pm | PLANT CELL WALL HYDROLASE STRUCTURE AND FUNCTION - CATALYTIC DOMAINS |
| Discussion Leader: Mirjam Czjzek (CNRS, France) |
10:05 am - 10:35 am | Cecile Herve (University of Leeds, UK) "The role of carbohydrate binding modules in the degradation of xylans in plant cell walls" |
10:35 am - 10:45 am | Discussion |
10:45 am - 11.20 am | Coffee Break |
11:20 am - 11:50 am | Brian Watson (University of Maryland, USA)
"Saccharophagus degradans 2-40 utilizes a novel group of processive endoglucanases to degrade cellulose" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:25 pm | Peter Biely (SAS , Slovakia) "Towards recognition of the structure, function and biotechnological potential of carbohydrate esterases" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | PLANT CELL WALL HYDROLASE STRUCTURE AND FUNCTION - CATALYTIC DOMAINS (CONTINUED) |
| Discussion Leader: Mirjam Czjzek (CNRS, France) |
7:30 pm - 8:00 pm | Richard Pickersgill (Queen Mary University of London, UK) "Molecular basis of the activity of pectin enzymes" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Jocelyn KC Rose (Cornell University, USA) "Plant cellulases" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Mats Sandgren (University of Agricultural Sciences, Sweden) "Structural characterization of a β-xylosidase and comparisons with other GH family 3 enzymes" |
9:20 pm - 9:30 pm | Discussion |
9:30 | Additional Discussions at Proctor Academy Clubhouse |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 10:45 am | PLANT CELL WALL HYDROLASE STRUCTURE AND FUNCTION - CATALYTIC DOMAINS (CONTINUED) |
| Discussion Leader: Mirjam Czjzek (CNRS, France) |
9:00 am - 9:30 am | Vincent Eijsink (Norwegian University of Life Sciences, Norway) "The roles of processivity and accessory proteins during enzymatic degradation of recalcitrant polysaccharides" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:10 am | Kiyohiko Igarashi (University of Tokyo, Japan) "Single-molecule imaging of cellobiohydrolases on highly crystalline cellulose using high-speed atomic force microscopy" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:45 am | General Discussion |
10:45 am - 11:10 am | Coffee Break |
11:10 am - 12:30 pm | REGULATION OF ENZYME EXPRESSION |
| Discussion Leader: Merja Penttilä (VTT, Finland) |
11:10 am - 11:40 am | Eric Martens (Washington University, USA) "Transcriptional Regulation of Glycoside Hydrolases in Bacteroides thetaiotaomicron" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:20 pm | David Bolam (Newcastle University, UK) "The mechanism of nutrient sensing in Bacteroides thetaiotaomicron" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:15 pm | REGULATION OF ENZYME EXPRESSION (CONTINUED) |
| Discussion Leader: Merja Penttilä (VTT, Finland) |
7:30 pm - 8:00 pm | Yuval Shoham (Technion, Israel) "Competing for carbon in the soil: the hemicellulolytic system of Geobacillus
stearothermophilus" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Bernhard Seiboth (Institute of Chemical Engineering, Austria) "Genome-wide approaches towards understanding cellulase production by Trichoderma reesei" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | General Discussion |
9:15 pm | Additional Discussions at Proctor Academy Clubhouse |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:55 am | RATIONAL DESIGN, DIRECTED EVOLUTION AND PROSPECTING FOR SUPERIOR ENZYMES |
| Discussion Leader: Harry Brumer (KTH, Sweden) |
9:00 am - 9:30 am | Suzanne Lantz (Genencor, USA) "Discovery and Development of Improved Enzymes for Ligno-Cellulosic Conversion" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:10 am | Jason Quinlan (Novozymes Denmark) "Improving enzymatic cellulose hydrolysis: effects of non-cellulose components of biomass feedstock" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:45 am | Coffee Break |
10:45 am - 11:00 am | General Discussion |
11:00 am - 12:30 pm | GENOMES |
| Discussion Leader: Bernard Henrissat (CNRS, France) |
11:00 am - 11:30 am | Pedro Coutinho (CNRS, France)
"Bacterial genomes" |
11:30 am - 11:40 am | Discussion |
11:40 am - 11:50 am | Irina Kataeva (UGA, USA)
"Physiology, Enzymology and Genome Sequence of Anaerocellum thermophilum DSM 6725, an Anaerobic Bacterium that Degrades Untreated Plant Biomass up to 90°C" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:05 pm | Jan-Hendrik Hehemann (CNRS, France)
"Porphyranase gene transfer from marine to human gut bacteria - the Sushi factor" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Harry Brumer (KTH, Sweden)
"CAZypedia" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:15 pm | GENOMES (CONTINUED) |
| Discussion Leader: Bernard Henrissat (CNRS, France) |
7:30 pm - 8:00 pm | Philip B. Pope (CSIRO, Australia) "The plant cell wall degrading capacity of the microbial community in marsupials" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Bryan White (Inst. Gen. Biol., USA)
"Cellulosomics, a gene-centric metagenomic approach for investigating the dynamics of cellulose-degrading specialist populations within global communities" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | General Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |