SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Enzyme - Substrate Interactions |
| Discussion Leader: Mike Himmel (National Renewable Energy Laboratory, USA) |
7:45 pm - 8:15 pm | Kiyohiko Igarishi (University of Tokyo, Japan) "Traffic jams reduce hydrolytic efficiency of cellulase on cellulose surface" |
8:15 pm - 8:25 pm | Discussion |
8:25 pm - 8:55 pm | Tina Jeoh (University of California Davis, USA) "An in vitro platform for nanometer-scale studies of enzyme-substrate interactions towards understanding the mechanisms of cell wall hydrolysis" |
8:55 pm - 9:05 pm | Discussion |
9:05 pm - 9:30 pm | General Discussion |
9:30 pm | Additional Discussions at Martin Institute |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Plant Cell Wall Architecture |
| Discussion Leader: Debra Mohnen (University of Georgia / BESC, USA) |
9:00 am - 9:30 am | William York (University of Georgia, USA) "Structure and biosynthesis of heteroxylans - an evolving perspective" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:10 am | Daniel Cosgrove (Penn State University, USA) "Does xyloglucan really function as a tether of cellulose networks in growing plant cell walls? - a study with family-12 endoglucanases" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:45 am | Group Photo / Coffee Break |
10:45 am - 11:15 am | Jaclyn DeMartini (University of California Riverside, USA) "Monitoring Effects of Pretreatment on Cell Wall Chemistry and Structure to Identify Characteristics that Affect Digestibility" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:55 am | Alexandra Fagerström (University of Copenhagen, Denmark) "Carbohydrate micro-arrays for carbohydrate active enzymes" |
11:55 am - 12:05 pm | Discussion |
12:05 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session 1 |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Cellulosome Structure and Function |
| Discussion Leader: Raphael Lamed (Tel Aviv University, Israel) |
7:30 pm - 8:00 pm | Sarah Morais (The Weizmann Institute of Science, Israel) "Cellulase- and hemicellulase-containing designer cellulosomes for the degradation of a natural wheat straw substrate" |
8:00 pm - 8:05 pm | Discussion |
8:05 pm - 8:35 pm | Yannick Bomble (National Renewable Energy Laboratory, USA) "Dissecting the Cellulosome Enzyme Complex: Assembly and Function" |
8:35 pm - 8:40 pm | Discussion |
8:40 pm - 9:10 pm | Steven Smith (Queen's University, Canada) "Cellulosome higher order structure and dynamics" |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:30 pm | General Discussion |
9:30 pm | Additional Discussions at Martin Institute |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Enzyme Structure and Function I |
| Discussion Leader: Mats Sandgren (Swedish University of Agricultural Sciences) |
9:00 am - 9:30 am | Priit Väljamäe (University of Tartu, Estonia) "Single-hit and single-turnover approaches for cellulase processivity" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:10 am | Takuya Ishida (University of Tokyo, Japan) "Crystal structure of GH family 74 xyloglucanase Cel74A from Hypocrea jecorina" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:50 am | Coffee Break |
10:50 am - 11:20 am | Nicole Koropatkin (University of Michigan, USA)
"The role of redundant starch-binding modules in the starch utilization system (sus) of Bacteroides thetaiotaomicron" |
11:20 am - 11:30 am | Discussion |
11:30 am - 12:00 pm | Lauren Sara Mckee (KTH, Sweden) "Engineering xylanase activity into an arabinofuranosidase that targets double arabinose substitutions in xylan" |
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session 1 |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Enzyme Structure and Function II |
| Discussion Leader: David Wilson (Cornell University, USA) |
7:30 pm - 8:00 pm | Matt Sweeney (Novozymes Inc., USA) "The function of GH61 proteins in cellulose depolymerization" |
8:00 pm - 8:05 pm | Discussion |
8:05 pm - 8:35 pm | William Beeson (University of California, Berkeley, USA) "Contribution of oxidative enzymes to the degradation of cellulose by filamentous fungi" |
8:35 pm - 8:40 pm | Discussion |
8:40 pm - 9:10 pm | Gustav Vaaje-Kolstad (Norwegian University of Life Sciences) "A missing link in the enzymatic degradation of recalcitrant polysaccharides" |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:30 pm | General Discussion |
9:30 pm | Additional Discussions at Martin Institute |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Regulation of Enzyme Expression |
| Discussion Leader: Jonathan Mielenz (Oak Ridge National Laboratory, USA) |
9:00 am - 9:30 am | Louise Glass (Energy Bioscience Institute, USA) "Systems biology approaches to dissect plant cell wall deconstruction by a model filamentous fungus" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:10 am | Verena Seidl-Seiboth (Vienna University of Technology, Austria) "Self vs. non-self: Fungal cell wall degradation in Trichoderma" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Yuval Shoham (Technion-IIT, Israel) "Sensing and reacting: the regulation of the cellulosomal genes in Clostridium thermocellum" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:55 am | David Keating (Great Lakes Bioenergy Research Centre, USA)
"Systems Biology of Lignocellulose Degradation by Cellvibrio japonicus" |
11:55 am - 12:05 pm | Discussion |
12:05 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session 2 |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | Genomics |
| Discussion Leader: Pedro Coutinho (Université Aix-Marseilles, CNRS - AFMB, France) |
7:30 pm - 8:00 pm | Warren Wakarchuk (National Research Council Canada) "Genomic analysis of Cellulomonas fimi: a lesson in using next generation sequencing for an old school microbe" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Christopher Hemme (University of Oklahoma, USA) "The Structure and Evolution of the Cellulosome" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:30 pm | General Discussion |
9:30 pm | Additional Discussions at Martin Institute |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Discovery and Design of Improved Enzymes |
| Discussion Leader: Harry Gilbert (Newcastle University) |
9:00 am - 9:30 am | Thijs Kaper (Genencor, a Danisco Division, USA) "Development of enzyme systems for saccharification of lignocellulosic feedstocks" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:10 am | Indira Wu (California Institute of Technology, USA) "Directed evolution of family 6 fungal cellobiohydrolase in yeast" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Nicolas Lopes Ferreira (IFP Energies Nouvelles, France)
"Evolved Cel3a beta-glucosidase improving the enzymatic cocktail of Trichoderma reesei CL847" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:55 am | Yoav Barak (The Weizmann Institute of Science, Israel) "Enhanced cellulose degradation by cellulosome-inspired nano-complexed enzymes" |
11:55 am - 12:05 pm | Discussion |
12:05 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | CAZy Research Applications |
| Discussion Leader: Colin Mitchinson (Genencor, a Danisco Division, USA) |
7:30 pm - 8:00 pm | Oliver Spadiut (Vienna University of Technology, Austria) "Building custom polysaccharides in vitro with a new glycosynthase and a glycosyltransferase" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Jean-Guy Berrin (INRA, France)
"Fungal CAZymes to Potentiate the Trichoderma reesei Secretome for Saccharification of Lignocellulosic Biomass" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | General Discussion |
9:20 pm - 9:30 pm | Conference Wrap Up |
9:30 pm | Additional Discussions at Martin Institute |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |