SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:45 pm | Welcome / Introductory Comments by GRC Site Staff |
7:45 pm - 9:30 pm | Keynote Session on the biosynthesis and biodegradation of terrestrial biomass |
| Discussion Leader: Tony Warren (University of British Columbia, Vancouver, CAN) |
7:45 pm - 8:25 pm | Jochen Zimmer (University of Virginia Medical School, Charlottesville, USA)
"The Structural Basis of Cellulose Biosynthesis" |
8:25 pm - 8:40 pm | Discussion |
8:40 pm - 9:20 pm | Bernard Henrissat (Architecture et Fonction des Macromolécules Biologiques, Centre National de la Recherche Scientifique, Marseille, FRA)
"Mining genomes: Contemporary insight into the breakdown of the plant cell wall via considered bioinformatics" |
9:20 pm - 9:30 pm | Discussion |
9:30 pm - | Additional Discussions at Proctor Academy Clubhouse |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 10:35 am | Building walls - Discovery and functional analysis of glycosyltransferases in plant genomes |
| Discussion Leader: Paul Dupree (University Of Cambridge, GBR) |
9:00 am - 9:25 am | Will York (Complex Carbohydrate Research Center, University of Georgia, Athens, USA)
"What's up with hemicelluloses? Structural diversity, function, evolution and biosynthesis" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Henrik Scheller (Joint BioEnergy Institute / Lawrence Berkeley National Laboratory / UC Berkeley, USA)
"Enzyme discovery in plant cell wall biosynthesis" |
10:00 am - 10:10 am | Discussion |
10:10 am | Coffee Break |
10:35 am - 12:30 pm | (Functional) Genomics of biomass deconstruction by microbial systems |
| Discussion Leader: Randy Berka (Novozymes, Inc., Davis, USA) |
10:35 am - 11:00 am | Dan Cullen (United States Department of Agriculture, Forest Products Laboratory, Madison, USA)
"Mechanisms of lignocellulose degradation inferred from genome analyses of wood decay fungi" |
11:00 am - 11:10 am | Discussion |
11:10 am - 11:35 am | Christina Moon (AgResearch Limited, Grasslands Research Centre, Palmerston North, NZL)
"Exploration of the rumen microbial metagenome and metasecretome for lignocellulolytic activities" |
11:35 am - 11:45 am | Discussion |
11:45 am - 12:10 pm | Paul Harris (Novozymes Inc., Davis, USA)
"The mating of omics research and commercial product development: From a glimmer in the eye to the ugly baby" |
12:10 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 8:10 pm | (Functional) Genomics of biomass deconstruction by microbial systems (continued) |
| Discussion Leader: Randy Berka (Novozymes, Inc., Davis, USA) |
7:30 pm - 8:00 pm | Eric Martens (University of Michigan, Ann Arbor, USA)
"Diversity and evolution of CAZyme-containing gene clusters in the human gut Bacteroidetes" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 9:30 pm | Carbohydrate recognition by non-catalytic proteins and modules |
| Discussion Leader: Birte Svensson (Danmarks Tekniske Universitet, Kongens Lyngby, DEN) |
8:10 pm - 8:40 pm | Harry Gilbert (Newcastle University, GBR)
"Some new insights into how CBMs can potentiate enzymatic function" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Alisdair Boraston (University of Victoria, CAN)
"Beyond the ABCs of CBMs" |
9:20 pm - 9:30 pm | Discussion |
9:30 pm - | Additional Discussions at Proctor Academy Clubhouse |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 11:10 am | Evolving methods to visualize carbohydrate-active enzyme activity in situ |
| Discussion Leader: Tina Jeoh (University of California, Davis, USA) |
9:00 am - 9:25 am | Bernd Nidetzky (Technische Universität Graz, AUT)
"In situ visualization of cellulase activity" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Emma Master (University of Toronto, CAN)
"Direct assessment and visualization of enzyme action on plant cell walls" |
10:00 am - 10:10 am | Discussion |
10:10 am | Coffee Break |
10:35 am - 11:00 am | Shi-You Ding (National Renewable Energy Laboratory, Golden, USA)
"Nanoscale accessibility facilitates plant cell wall digestibility by cellulases" |
11:00 am - 11:10 am | Discussion |
11:10 am - 12:30 pm | Cellulosomics |
| Discussion Leader: Steven Smith (Queens University, Kingston, CAN) |
11:10 am - 11:35 am | Ed Bayer (Weizmann Institute of Science, Rehovot, ISR)
"The 30th anniversary of the discovery of the cellulosome: Personal reflections and new stuff" |
11:35 am - 11:45 am | Discussion |
11:45 am - 12:10 pm | Carlos Fontes (Universidade Técnica de Lisboa, POR)
"The cohesin-dockerin interaction: Marital fidelity or polygamy?" |
12:10 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Oxidative polysaccharide degradation |
| Discussion Leader: Jean-Guy Berrin (Biotechnologie des Champignons Filamenteux, Institut National de la Recherche Agronomique, Marseille, FRA) |
7:30 pm - 8:00 pm | Gideon Davies (University of York, GBR)
"Structural and mechanistic insight into the oxidative cleavage of cell wall polysaccharides" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Vincent Eijsink (Universitetet for miljø- og biovitenskap, Ås, NOR)
"Structure and function of copper-dependent lytic polysaccharide monooxygenases" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Roland Ludwig (Universität für Bodenkultur, Wien, AUT)
"Viribus unitis: The interaction of glycoside hydrolase family 61 enzymes and cellobiose dehydrogenases towards oxidative cellulose degradation" |
9:20 pm - 9:30 pm | Discussion |
9:30 pm - | Additional Discussions at Proctor Academy Clubhouse |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Structure and function of carbohydrate-active enzymes |
| Discussion Leaders: Mirjam Czjzek (Station Biologique de Roscoff, Centre National de la Recherche Scientifique & Université Pierre et Marie Curie, FRA) and Tracey Gloster (University of St. Andrews, GBR) |
9:00 am - 9:25 am | Stephen Withers (University of British Columbia, Vancouver, CAN)
"New probes for screening and assaying glycan-degrading enzymes" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Shinya Fushinobu (University of Tokyo, JPN)
"Structure of a glycoside hydrolase with a novel catalytic machinery" |
10:00 am - 10:10 am | Discussion |
10:10 am | Coffee Break |
10:35 am - 11:00 am | Carme Rovira (Universitat de Barcelona, ESP)
"An atomistic view to glucan hydrolysis by QM/MM and metadynamics methods"
|
11:00 am - 11:10 am | Discussion |
11:10 am - 11:35 am | Michael Nash (Ludwig-Maximilians-Universität, München, GER)
"Single-Molecule Dissection of the Cohesin-Dockerin Comple"
|
11:35 am - 11:45 am | Discussion |
11:45 am - 12:10 pm | Data Blitz
|
| Short presentations from selected Gordon Research Seminar attendees and other junior scientists |
12:10 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | Structure and function of carbohydrate-active enzymes (continued) |
| Discussion Leader: Yuval Shoham (Technion - Israel Institute of Technology, Haifa, ISR) |
7:30 pm - 7:55 pm | David Bolam (University of Newcastle, UK)
"Xylan degradation by human gut Bacteroides - it's more complex than you think"
|
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Henrik Hansson (Sveriges lantbruksuniversitet, Uppsala, SWE)
"New structural insights into GH6 cellobiohydrolases" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:00 pm | André Damásio (Brazilian Bioethanol Science and Technology Laboratory)
"Functional analysis of fungal endoglucanases from glycoside hydrolase family 12"
|
9:00 pm - 9:05 pm | Discussion |
9:05 pm - 9:25 pm | Claire Dumon (Institut National de la Recherche Agronomique, Toulouse, FRA)
"Deep inside the GH62 arabinofuranosidase family"
|
9:25 pm - 9:30 pm | Discussion |
9:30 pm - | Additional Discussions at Proctor Academy Clubhouse |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 10:35 am | Marine Biomass Saccharification and Conversion |
| Discussion Leader: Pedro Coutinho (Aix Marseille Université, ESIL Polytech & Architecture et Fonction des Macromolécules Biologiques, Centre National de la Recherche Scientifique, Marseille, FRA) |
9:00 am - 9:25 am | Jan-Hendrik Hehemann (Massachusetts Institute of Technology, Cambridge, USA)
"Effects of habitat and life-style on carbohydrate resource partitioning in algae-degrading microbes" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Yasuo Yoshikuni (Bio Architecture Lab, Berkeley, USA)
"An engineered microbial platform for direct biofuel production from brown macroalgae" |
10:00 am - 10:10 am | Discussion |
10:10 am | Coffee Break |
10:35 am - 12:30 pm | Endogenous Glycosidases in the Plant Apoplast |
| Discussion Leader: Daniel Cosgrove (Pennsylvania State University, University Park, USA) |
10:35 am - 11:00 am | Jens Eklöf (Novozymes A/S, Copenhagen, DEN)
"Endogenous plant endo-glucanases" |
11:00 am - 11:10 am | Discussion |
11:10 am - 11:35 am | Javier Sampedro (Universidad de Santiago de Compostela, ESP)
"The role of exo-glycosidases in xyloglucan metabolism in planta" |
11:35 am - 11:45 am | Discussion |
11:45 am - 12:10 pm | Markus Pauly (Energy Biosciences Institute / UC Berkeley, USA)
"The maturation of plant wall polymers by plant hydrolases in the apoplast" |
12:10 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Inspired applications and future directions |
| Discussion Leader: Kiyohiko Igarashi (University of Tokyo, JPN) |
7:30 pm - 8:00 pm | Markus Linder (Aalto University, Helsinki, FIN)
"From CBMs to bioengineered nanomaterials" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | John Evans (POET, USA)
"Pretreatment and saccharification of lignocellulosic biomass: The POET experience" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:10 pm | Mike Himmel (National Renewable Energy Laboratory, Golden, USA)
"Life at the interface of fundamental cellulase research and government/industrial liaison" |
9:10 pm - 9:20 pm | Discussion |
9:20 pm - 9:30 pm | Wrap-up |
9:30 pm - | Additional Discussions at Proctor Academy Clubhouse |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |