Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Cellular Identification and Interactions
Discussion Leader: Markus Harrigan (The Ohio State University, United States)
3:45 pm - 4:05 pm
Faith Brennan (The Ohio State University, United States)
"Microglia Coordinate Cellular Interactions During Spinal Cord Repair"
4:05 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
Isaura Martins (Instituto de Medicina Molecular - Lobo Antunes , Portugal)
"Targeting Senescent Cells Improves Functional Recovery After Spinal Cord Injury"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Axonal Regeneration and Sprouting
Discussion Leader: Timothy Faw (Duke University, United States)
7:30 pm - 7:50 pm
Arthur Sefiani (Texas A&M College of Medicine, United States)
"Novel Adult Brain Processing Method Reveals Age-, Sex-, and Species-Dependent Effects of Pharmaceutical Compounds on Neuron Survival and Neuritogenesis"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Nisha Iyer (Tufts University, United States)
"4 Steps to Make Every Neuron in the Human Spinal Cord"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Lyandysha Zholudeva (Gladstone Institutes, United States)
"Engineering Human Spinal Interneurons for Spinal Cord Repair"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Xuewei Wang (Johns Hopkins University School of Medicine, United States)
"Targeting Ezh2 histone methyltransferase to enhance mammalian axon regeneration in the peripheral and central nervous systems"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Carolin Ruven (Weill Cornell Medicine, United States)
"Microsurgical Lesions Identify Segmentally Distinct Responses of Axotomized Corticospinal Neurons"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Vinicius Duarte (University of California, Irvine, United States)
"The Role of Early Calcium Signaling on Dendrite Regeneration"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Inflammation and Neural Targeting
Discussion Leader: Elham Asghari Adib (University of Michigan, United States)
9:00 am - 9:20 am
Bente Winkler (University of Muenster, Germany)
"Brain Inflammation Triggers Macrophage Invasion Across the Blood-Brain Barrier in Drosophila During Pupal Stages"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Katherine Mifflin (The Ohio State University, United States)
"High Level Spinal Cord Injury Impairs Pulmonary Immune Function"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Ryan Passino (University of Michigan, United States)
"Integrin-aM/CD11b has an Inhibitory Effect on Optic Nerve Regeneration"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
Xiaofei Guan (Weill Cornell Medicine, United States)
"Multi-Photon Imaging of Corticospinal Tract Target Interneurons"
10:20 am - 10:30 am
Discussion
10:30 am - 10:40 am
Lauren Walker (University of Pennsylvania, United States)
"Knowing Where to Re-Grow: Identification of Extrinsic Cues Promoting Target-Selective Axon Regeneration"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Juhi Samal (Duke University, United States)
"Glycan Cues in Modulating Post-Stroke Neuro-Inflammatory Responses to Promote Brain Repair"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Mentorship Panel
Discussion Leader: Ana Vivinetto (Burke Neurological Institute, United States)
1:30 pm - 2:30 pm
Panel Discussion
Career Advice from Senior Investigators
Lyn Jakeman (NIH/NINDS, United States)
Elizabeth Bradbury (King's College London, United Kingdom)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes