SUNDAY |
4:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | INTEGRATING BIODEFENSE WITH BASIC SCIENCE |
| Discussion Leader: Michael S. Ascher (Lawrence Livermore National Laboratory) |
7:40 pm - 8:25 pm | Michael Kurilla (NIAID, NIH)
"Addressing Infectious Disease Product Development for BioDefense and Public Health" |
8:25 pm - 8:35 pm | Discussion |
8:35 pm - 9:20 pm | C.J. Peters (University of Texas Medical Branch)
"Biodefense Today and Tomorrow: Rift Valley Fever Exemplifies the Challenges" |
9:20 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Frontiers of viral pathogenesis |
| Discussion Leader: Michael Buchmeier (Scripps Research Institute) |
9:00 am - 9:50 am | Benhur Lee (UCLA)
"Pathobiology of Nipah and Hendra Virus Entry" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:20 am | Grant McFadden (University of Florida)
"Poxvirus pathogenesis and tropism: The role of immune evasion strategies" |
11:20 am - 11:30 am | Discussion |
11:30 am - 12:20 pm | Connie Schmaljohn (USAMRIID)
"Directed molecular evolution for vaccines and therapeutics against biodefense pathogens" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Countermeasures for Viral Biothreat Agents Inspired by Studies of Pathogenesis in Animal Models |
| Discussion Leader: Peter B. Jahrling (NIAID, NIH) |
7:30 pm - 8:00 pm | Robert Kadlec (PRTM)
"Pandemic Influenza Preparedness: Observations on the Federal Response" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Dennis Hruby (SIGA Technologies)
"Development of a Smallpox Antiviral Drug: Trials and Tribulations" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Lisa Hensley (USAMRIID)
"The Role of the Anticoagulant Protein C System in Ebola Hemorrhagic Fever: An Intervention Study in Nonhuman Primates" |
9:20 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Nanotechnology-inspired chemical and biological sensing devices |
| Discussion Leader: Jeff Tok (Lawrence Livermore National Laboratory) |
9:00 am - 9:35 am | Nicholas Fischer (Lawrence Livermore National Laboratory)
"Next Generation Nanobiosensors for Biosecurity Applications" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:20 am | Hedi Mattoussi (Naval Research Laboratory)
"Quantum dot-bioreceptor conjugates as substrates for sensing small and large molecule targets" |
10:20 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:35 am | Chad Mirkin (Northwestern University)
"The Bio-Barcode Assay: Towards PCR-like Sensitivity for Proteins, Nucleic Acids, Small Molecules, and Metal Ions" |
11:35 am - 11:45 am | Discussion |
11:45 am - 12:20 pm | Joseph Wang (Arizona State University)
"Nanoparticle-Based Electronic Monitoring of Biomolecular Interactions" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | DNA MICROARRAYS - PAST, PRESENT AND FUTURE |
| Discussion Leader: Paul Hoeprich, Jr. (Lawrence Livermore National Laboratory) |
7:30 pm - 7:40 pm | Paul Hoeprich, Jr. (Lawrence Livermore National Laboratory)
"A brief history of microarray technology" |
7:40 pm - 8:00 pm | Tom Albert (NimbleGen)
"Advances in maskless microarray technology" |
8:00 pm - 8:20 pm | Leo Brizuela (Agilent)
"Translating pathogen's genome information into microarray tools for discovery and diagnostic in biodefense" |
8:20 pm - 8:40 pm | Giulia Kennedy (Affymatrix)
"Multi-pathogen detection using high-density oligonucleotide arrays" |
8:40 pm - 9:00 pm | Hui (Robin) Liu (Combimatrix)
"Approaches to field-based pan pathogen detection with array technologies and electrochemical detection" |
9:00 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | BACTERIAL PATHOGENESIS |
| Discussion Leader: Emilio Garcia (Lawrence Livermore National Laboratory) |
9:00 am - 9:50 am | Patrick Chain
"Yersinia pestis: Diversity and evolution of a recently emerged clone" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:20 am | Renee Tsolis (University of California, Davis)
"Immune evasion by Brucella" |
11:20 am - 11:30 am | Discussion |
11:30 am - 12:20 pm | Thomas Kozel (University of Nevada, Reno)
"Targeting the Bacillus anthracis capsule for immunodiagnosis and immunoprotection" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | CLOSTRIDIAL NEUROTOXINS: FROM GENOME TO THERAPY |
| Discussion Leader: Paul Jackson (Lawrence Livermore National Laboratory) |
7:30 pm - 8:00 pm | Karen Hill (Los Alamos National Laboratory)
"Genetic diversity among botulism neurotoxin producing clostridial strains" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | John Barr (CDC)
"Detection of botulism toxin" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | James Marks (UCSF)
"Engineering a recombinant antitoxin for botulinum neurotoxins A, B, and E" |
9:20 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | 21st Century FMD Biosurveillance, Modeling and Molecular Phylogeny |
| Discussion Leader: James Kvach (CBRTA) |
9:00 am - 9:50 am | Mark Thurmond (UC Davis)
"Global surveillance for foot-and-mouth disease" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:20 am | Hsinchun Chen (University of Arizona)
"The BioPortal informatics infrastructure" |
11:20 am - 11:30 am | Discussion |
11:30 am - 12:20 pm | Nick Knowles (Institute for Animal Health)
"FMD phylogenetics" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | ISSUES AND ADVANCES IN ENVIRONMENTAL DETECTION |
| Discussion Leader: Cheryl Kuske (Los Alamos National Laboratory) |
7:30 pm - 8:00 pm | Cheryl Kuske (Los Alamos National Laboratory)
"Detection of bacterial pathogens and their close relatives in urban environments" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Charles Haas (Drexel University)
"Connecting a detect/nondetect to a risk: What we think we know and what we know we don't know" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Allen Northrup (Microfludics Systems)
"Microfluidics-based Airborne Pathogen Detection Systems" |
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |