Sunday |
4:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Session: Global Environmental Change: Impacts on Biosecurity |
| In 2011 the United Nations Security Council
identified climate change as a possible threat to global peace and security. Two outstanding keynote speakers will address
possible connections between environmental change, terrorism, and security. It
is designed to introduce crosscutting concepts that
for many in the audience, should bridge disciplinary
boundaries by uniting core ideas throughout the broad areas of terrorism,
defenses against terrorism, and security. |
| Discussion Leader: Steven Blanke (University of Illinois, USA) |
7:40 pm - 7:50 pm | Introduction by Discussion Leader |
7:50 pm - 8:30 pm | C. Ben Beard (Centers for Disease Control and Prevention, USA) "Climate Change and the Emergence of Vector-Borne Disease" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:20 pm | James Stack (Kansas State University, USA) "Climate Change and Plant Biosecurity - A New World Disorder?" |
9:20 pm - 9:30 pm | Discussion |
Monday |
8:30 am | Group Photo |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Countermeasures to Biological Threats |
| This session will will highlight basic research characterizing both human and pathogen
responses to medical countermeasures. |
| Discussion Leader: Petra Oyston (Dstl Porton Down, United Kingdom) |
9:00 am - 9:15 am | Introduction by Discussion Leader |
9:15 am - 9:45 am | Catharine Bosio (Rocky Mountain Laboratory, USA) "Comparison of Immune Responses to Francisella Strains for Identification of Mechanisms of Virulence and Vaccine Design" |
9:45 am - 9:55 am | Discussion |
9:55 am - 10:25 am | Gene Olinger (National Institutes of Health / National Institute of Allergy and Infectious Diseases Contractor, USA) "Identifying Vaccines and Therapeutics for Viral Biothreat Infections" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:35 am | Daniel Kadouri (Rutgers School of Dental Medicine, USA) "Predatory Bacteria to Control Lung Infections" |
11:35 am - 11:45 am | Discussion |
11:45 am - 12:15 pm | Olga Lomovskaya (The Medicines Company, USA) "Targeting Antibiotic Resistance in Gram-Negative Bacteria" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Countermeasures to Chemical Threats |
| This session will explore novel and promising approaches for mitigating human
exposure to chemical warfare agents. |
| Discussion Leader: Clement Furlong (University of Washington School of Medicine, USA) |
7:30 pm - 7:35 pm | Introduction by Discussion Leader |
7:35 pm - 8:05 pm | Patrick McNutt (USAMRICD, USA) "Development and Testing of Catalytic Bioscavengers for Prophylactic and Therapeutic Treatment of OP Exposures" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:45 pm | Chris Green (Dstl Porton Down, United Kingdom) "Alternative Approaches to Improving the Treatment of Organophosphate Poisoning" |
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Franz Worek (Bundeswehr Institute of Pharmacology & Toxicology, Germany) "Nerve Agent Countermeasures: The Long Way to a Universal Antidote" |
9:20 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Cutting Edge Research on High Threat Agents |
| Speakers will explore the development and applications of new technologies to understand and mitigate threats due to pathogens and toxins. |
| Discussion Leader: Anne Boyer (Centers for Disease Control and Prevention, USA) |
9:00 am - 9:15 am | Introduction by Discussion Leader |
9:15 am - 9:45 am | Fabio Rinaldi (Cornell University, USA) "Targeted Gene Regulation and Editing with Tal Effectors to Understand and Combat Pathogens" |
9:45 am - 9:55 am | Discussion |
9:55 am - 10:25 am | Suzanne Kalb (Centers for Disease Control and Prevention, USA) "Advanced Mass Spectrometry for Unraveling Complexities in Biological Activities and Structures of Botulinum Neurotoxins and Their Associated Proteins" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:35 am | Bryan Krantz (University of Maryland, Baltimore, USA) "Detecting a Virulence Factor with Many Disguises: Anthrax Toxin's Heterogeneous Assembly Mechanism Controls Its Stability" |
11:35 am - 11:45 am | Discussion |
11:45 am - 12:15 pm | David T.S. Hayman (Massey University, New Zealand) "Conservation as Vaccination: A Way to Prevent the Next Ebola Crisis?" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Responding to the NAS Report: New Research Applications to Enhance Microbial Forensic Investigation |
| This session explores new research approaches in response to a recent study (2013) by the National Academies of Science, entitled “Science Needs for
Microbial Forensics: Developing an Initial International Roadmap,” which outlined
critical needs in the development of technological and operational strategies
for microbial forensics investigations. |
| Discussion Leader: Stephen Morse (Centers for Disease Control and Prevention, USA) |
7:30 pm - 7:35 pm | Introduction by Discussion Leader |
7:35 pm - 8:05 pm | Paul Keim (Northern Arizona University, USA) "Genomic Analysis, Population Genetics, and Attribution" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Karen Wahl (Pacific Northwest National Laboratory, USA) "Mass Spectrometry for
Non-Genomic Characterization of Biological Samples" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Thomas Slezak (Lawrence Livermore National Lab, USA) "Addressing Current Shortcomings
of Unbiased NGS for Culture-Free Microbial Forensics Applications" |
9:20 pm - 9:30 pm | Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Food Defense: Research to Assure Food Safety and Security |
| This session will feature talks on leading research to detecting and identifying
catastrophic agents with food, including a talk by the Director of the National
Center for Food Protection and Defense. |
| Discussion Leader: Jacqueline Fletcher (Oklahoma State University, USA) |
9:00 am - 9:15 am | Introduction by Discussion Leader |
9:15 am - 9:45 am | John Besser (Centers for Disease Control and Prevention, USA) "Novel Detection Methods for Identifying
Catastrophic Agents in Food" |
9:45 am - 9:55 am | Discussion |
9:55 am - 10:25 am | Amy Kircher (National Center for Food Protection and Defense, USA) "Big Data - Deriving
Insights from Global Data Sets to Predict and Warn" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:35 am | Lesley Chesson (IsoForensics, Inc., USA) "Authentication and Traceability of Adulterated Foods Using Isotope Analysis Techniques" |
11:35 am - 11:45 am | Discussion |
11:45 am - 12:15 pm | Harshini Mukundan (New Mexico Consortium / Los Alamos National Lab., USA) "Biomarkers for Human Pathogens in Metals" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Late-Breaking Topics in Chemical and Biological Terrorism Defense |
| This session provides a vehicle for innovative and recent results to be
introduced to the larger GRC audience. |
| Discussion Leader: Carol Linden (US Department of Health and Human Services, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:10 pm | Thomas Geisbert (University of Texas Medical Branch, USA) "Meeting the Ebola Challenge: Vaccines and Treatment" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:30 pm | Selected from Poster Abstracts: Phillip Beske (US Army Medical Research Institute of Chemical Defense, USA) "The Use of Synaptic Function-Based Assays in Stem Cell-Derived Neurons for the Identification of Novel Compounds that Rescue Synaptic Paralysis Induced by Botulinum Neurotoxins" |
8:30 pm - 8:35 pm | Discussion |
8:35 pm - 8:45 pm | Selected from Poster Abstracts: Robin Holland (University of Illinois, Urbana-Champaign, USA) "Mitochondrial Targeting by Human Pathogenic Microbes" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:00 pm | Selected from Poster Abstracts: Isamar Ortiz (Pennsylvania State University, USA) "Self-Powered Enzyme Pumps for Detecting and Reacting with Sepcific Analytes" |
9:00 pm - 9:05 pm | Discussion |
9:05 pm - 9:15 pm | Selected from Poster Abstracts: Emily Thi (Tekmira Pharmaceuticals, Canada) "Development of Lipid Nanoparticle siRNA-Based Therapeutics for Hemorrhagic Fever Virus Infection" |
9:15 pm - 9:20 pm | Discussion |
9:20 pm - 9:30 pm | General Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Host Interactions with Chemical and Biological Agents |
| Speakers will present research on host responses to
invasive chemical or biological agents, with the translational goal of
identifying pathways, molecules, and other targets at which to direct effective
countermeasures. |
| Discussion Leader: John Hardham (Zoetis, USA) |
9:00 am - 9:15 am | Introduction by Discussion Leader |
9:15 am - 9:45 am | Barbara Valent (Kansas State University, USA) "Filamentous Plant Pathogen Effectors" |
9:45 am - 9:55 am | Discussion |
9:55 am - 10:25 am | Annette Schmidt (Bundeswehr Institute of Pharmacology & Toxicology, Germany) "Experimental Approaches to Treat Chemical Threat Agent Induced Chronic Wounds" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:35 am | Tom Kawula (University of North Carolina, USA) "Francisella tularensis Cell to Cell Spread" |
11:35 am - 11:45 am | Discussion |
11:45 am - 12:15 pm | Jonathan Arzt (USDA Agricultural Research Service, USA) "Virulence
Determinants of Foot-and-Mouth Disease Virus (FMDV) with Emphasis on the Leader
Protein" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Real Time Detection and Decontamination of Chemical and Biological Threat Agents |
| Presentations will highlight cutting edge
approaches for early and accurate threat detection of biological or chemical
threat agents, as well as effective decontamination materials and strategies. |
| Discussion Leader: Thomas Blake (Centers for Disease Control and Prevention, USA) |
7:30 pm - 7:35 pm | Introduction by Discussion Leader |
7:35 pm - 8:00 pm | Ronald Manginell (Sandia National Labs, USA) "Hand-Held Systems for Real-Time Detection of Chemical and Biological Threats" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | David Schmale (Virginia Tech University, USA) "Drone-ing for Biological Threat Agents in the Lower Atmosphere" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Yuehe Lin (Washington State University, USA) "Using Functional Nanomaterials in the Development of Environmental and Biomedical Sensors" |
9:20 pm - 9:30 pm | Discussion |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |