SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | KEYNOTE ADDRESSES |
| |
7:30 pm | T. Kodadek and J. Aldrich
Introductory Remarks |
7:50 pm - 8:40 pm | B. Chait, (Rockefeller)
"Recent Advances In Protein and Peptide Mass Spectromety" |
8:40 pm - 9:30 pm | B. Koblika (Stanford) "Conformational Dynamics of Beta 2 Adrenoceptor Activation" |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | COMBINATORIAL CHEMISTRY |
| Discussion Leader: A. Mapp (Michigan) |
9:00 am - 9:30 am | A. Mapp (Michigan)
"Targeting the transcriptional machinery with unique artificial transcriptional regulators" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:10 am | G. Nolan (Stanford)
"Fluorescent dye-capturing peptides for visualization and chemical
genetics" |
10:10 am - 10:20 am | Discussion |
10:20 am - 11:05 am | Coffee Break & Group Photo |
11:05 am - 11:35 am | Tom Kodadek (UT-Southwestern)
"New chemical tools for proteomics research"
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11:35 am - 12:05 pm | A. Schepartz (Yale)
"Miniature Proteins" |
12:05 pm - 12:25 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | NOVEL APPLICATIONS IN CHEMISTRY & BIOLOGY |
| Discussion Leader: A. Belcher (MIT) |
7:30 pm - 8:00 pm | A. Belcher (MIT)
"Using Nature's tools to grow and assemble magnetic and semiconductor nanomaterials" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | T. Deming (UCSB)
"Synthesis and Properties of Amphiphilic Block Co-Polypeptides" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | P. Dervan (Caltech)
"Design of Artificial Transcription Factors" |
9:20 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | CELL TRANSPORT AND TARGETING |
| Discussion Leader: K. Brown (UT-Southwestern) |
9:00 am - 9:30 am | H. Szeto (Cornell)
"Design of Cell-permeable, Mitochondria-targeted, Antioxidant peptides" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:10 am | K. Brown (UT-Southwestern)
"Identifying cellular zip codes: Non-biased Approaches for Isolating Peptidic Cell-targeting Reagents" |
10:10 am - 10:20 am | Discussion |
10:20 am | Coffee Break |
10:45 am - 11:15 am | B. Peterson (Penn St.)
"Synthetic Mimics of Mammalian Cell Surface Receptors" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:55 am | M. Miller (Notre Dame)
"Design, Syntheses and Studies of Microbe Targeted Drug Delivery Agents Using Microbial Iron Assimilation Processes" |
11:55 am - 12:05 am | Discussion |
12:05 am - 12:25 pm | Stephen M. Fuchs (University of Wisconsin) "Pathway for Polyarginine Entry into Mammalian Cells" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | PEPTIDE-RECEPTOR INTERACTIONS |
| Discussion Leader: C. Deber (Toronto) |
7:30 pm - 8:00 pm | F. Marassi (Burnham Inst.)
"Solid-state NMR Structure Determination of Membrane Peptides and Proteins" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | R. Murphy (Wisconsin)
"Biophysical Studies on the Interaction of Self-associating Peptides with Lipid Bilayers" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | T. Kubiak (Pfizer)
"Newly Deorphaned Invertebrate Neuropeptide GPCRs" |
9:20 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | PEPTIDE DESIGN AND SYNTHESIS |
| Discussion Leader: R. Freidinger (Merck) |
9:00 am - 9:30 am | S. Miller (Boston College)
"An Approach to Asymmetric Synthesis Based on "Biomimetic" Catalysis" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:10 am | J. Aldrich (Kansas)
"A Tale of Two Labels: the Design and Synthesis of Dual Labeled Peptides as Pharmacological Tools" |
10:10 am - 10:20 am | Discussion |
10:20 am | Coffee Break |
10:45 am - 11:15 am | B. Iverson (UT-Austin)
"Now Accepting Donations: Aromatic Donor-Acceptor Interactions in the Assembly of Peptide Derivatives In Aqueous Solution" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:55 am | Victor J. Hruby (University of Arizona) "New Insights into Signal Transduction by GPCRs Using Two New Biophysical Methods: Plasmon Waveguide Resonance (PWR) Spectroscopy and Two Photon Fluorescence Laser Microscopy" |
11:55 am - 12:05 am | Discussion |
12:05 am - 12:25 pm | Luisa Bracci (University of Siena) "Highly Stable Bioactive Dendrimeric Peptides" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | PHARMACEUTICAL APPLICATIONS OF PEPTIDES |
| Discussion Leader: B. Morgan (Praceis) |
7:30 pm - 8:00 pm | David Israel (Praceis)
"Clinical Experience With Peptide-Based Drugs in Prostate Cancer and Alzheimer's Disease" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | J. Dwyer (Trimeris)
"Discovery, Development and Clinical Experience with Fuseon, the First Clinical Fusion Inhibitor" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | R. DiMarchi (Indiana)
"Development of Peptide-Based Medicines for Treatment of Endocrine Diseases" |
9:20 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | PROTEOMICS AND ANALYTICAL TECHNIQUES |
| Discussion Leader: T. Kodadek (UT-Southwestern) |
9:00 am - 9:15 am | Y.-S. Lee (Seoul National University)
"Peptide Synthesis On A Slide Glass By Spotting Method" |
9:15 am - 9:20 am | Discussion |
9:20 am - 9:35 am | S. Lokey (UC-Santa Cruz)
"A Proteomics Approach To Understanding the Mechanism
of Action of Cyclic Peptide Modulators of Actin Assembly" |
9:35 am - 9:40 am | Discussion |
9:40 am - 10:10 am | H. Mihara (Tokyo Inst. Technol.)
"Peptide Microarrays Using Designed Libraries For
Development Of Protein Chips" |
10:10 am - 10:20 am | Discussion |
10:20 am | Coffee Break |
10:45 am - 11:15 am | D. Hunt (Virginia)
"Analysis Of Differential Protein Expression, The Phosphoproteome, And
The Histone Code By Mass Spectrometry" |
11:15 am - 11:25 am | Discussion |
11:25 am - 12:05 am | Business Meeting |
11:55 am - 12:05 am | Discussion |
12:05 am - 12:25 pm | R. Hammer (LSU)
"Unprecedented stoichiometric inhibition of fibrillogenesis of
amyloid beta protein by small peptides" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | DU VIGNEAUD AWARDS |
| Discussion Leader: J. Aldrich (Kansas) |
7:30 pm - 8:30 pm | Du Vigneaud Award Address #1
Stephen Kent (University of Chicago)
"A Revolution in the Making: Chemical Ligation Methods for the Study of Protein Biology"
|
8:30 pm - 9:30 pm | Du Vigneaud Award Address #2
Dieter Seebach (ETH Zürich)
"How we stumbled into peptide chemistry, and where we have arrived at"
|
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |