| SUNDAY |
| 4:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:00 pm - 8:00 pm | Opening Reception |
| 8:00 pm - 9:30 pm | KEYNOTE ADDRESSES |
| 8:00 pm - 8:05 pm | R. Hodges and D. Mierke
Introductory Remarks |
| 8:05 pm - 8:45 pm | Roger M. Freidinger
"Peptidomimetics and Nonpeptide Ligands for Peptide Receptors: Bradykinin B1 Antagonists" |
| 8:50 pm - 9:30 pm | Luis Moroder
"Collagen peptides as synthetic models of the extracellular matrix" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | G-PROTEIN COUPLED RECEPTORS |
| Discussion Leader: Dale Mierke (Brown University) |
| 9:00 am - 9:25 am | Roland Riek (Salk)
"Structural insights into the peptide ligand-receptor interactions of a GPCR of family B" |
| 9:25 am - 9:35 am | Discussion |
| 9:35 am - 10:00 am | Alessandro Bisello (University Pittsburgh)
"Accessory proteins for G protein-coupled receptors" |
| 10:00 am - 10:10 am | Discussion |
| 10:10 am - 10:40 am | Coffee Break |
| 10:40 am - 11:05 am | Sam R.J. Hoare (Neurocrine)
"Mechanisms of ligand binding to Class B G-protein-coupled receptors" |
| 11:05 am - 11:15 am | Discussion |
| 11:15 am | Group Photo |
| 11:35 am - 12:00 pm | Indraneel Ghosh (University of Arizona)
"Quantum Dots for targeting GPCRs" |
| 12:00 pm - 12:10 pm | Discussion |
| 12:10 pm - 12:20 pm | Poster Presentation: William Ja (California Institute of Technology)
"In Vitro Selection of Peptides that Antagonize Methuselah and Extend Drosophila Lifespan" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | PEPTIDES IN CANCER BIOLOGY |
| Discussion Leader: Kit Lam (University California, Davis) |
| 7:30 pm - 7:55 pm | Kit Lam (University California, Davis)
"From Combinatorial Chemistry to Cancer Targeting" |
| 7:55 pm - 8:05 pm | Discussion |
| 8:05 pm - 8:30 pm | Terry Moody (National Cancer Institute)
"Bombesin and VIP receptors in lung cancer" |
| 8:30 pm - 8:40 pm | Discussion |
| 8:40 pm - 8:50 pm | Poster Presentation: Luisa Bracci (University of Siena)
"Branched Neurotensin for Tumor-Selective Targeting" |
| 8:50 pm - 8:55 pm | Discussion |
| 8:55 pm - 9:20 pm | Ziwei Huang (Burnham Institute)
"Peptides and peptidomimetics targeting apoptotic mechanisms of cancer cells" |
| 9:20 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | DESIGN/SYNTHESIS PEPTIDOMIMETICS |
| Discussion Leader: Armin Geyer (U. Marburg) |
| 9:00 am - 9:25 am | Christian Schafmeister (U. Pittsburgh) |
| 9:25 am - 9:35 am | Discussion |
| 9:35 am - 10:00 am | William Lubell (U. Montreal)
"New synthetic methodology for making old mimics" |
| 10:00 am - 10:10 am | Discussion |
| 10:10 am - 10:20 am | Poster Presentation: Michael R. Carrasco (Santa Clara University)
"Synthesis of Neolipopeptides by Chemoselective Alkylation of N-Alkylaminooxy-Containing Peptides" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:55 am | Coffee Break |
| 10:55 am - 11:20 am | Mark Spaller (Wayne State University)
"Ligand Design for PDZ Domain Proteins: From Thermodynamic Analysis to Biological Probes" |
| 11:20 am - 11:30 am | Discussion |
| 11:30 am - 11:55 am | Marcey Waters (U. North Carolina)
"Controlling Biomolecular Recognition with Designed Peptides" |
| 11:55 am - 12:05 pm | Discussion |
| 12:05 pm - 12:25 pm | David Perrin (University of British Columbia)
"Synthetic Approaches to Phakellistatin, Amanitin, and Phalloidin - Expeditious Synthesis of Combinatorial Arrays Thereof" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | PEPTIDES: MICROBIOLOGY/IMMUNOLOGY |
| Discussion Leader: Pravin T.P. Kaumaya (Ohio State University) |
| 7:30 pm - 7:55 pm | Pravin T.P. Kaumaya (Ohio State University)
"Combined Peptide Vaccines and Therapeutic Approaches For Optimizing Specific Immune Responses and Clinical Efficacy" |
| 7:55 pm - 8:05 pm | Discussion |
| 8:05 pm - 8:30 pm | Esteban Celis (LSU Health Sciences)
"Development of Multi-Epitope Peptide-Based Vaccines for Cancer" |
| 8:30 pm - 8:40 pm | Discussion |
| 8:40 pm - 8:50 pm | Poster Presentation: Brian Tripet (University of Colorado)
"Design and Study of Neutralizing Antibodies Against SARS-CoV Entry" |
| 8:50 pm - 8:55 pm | Discussion |
| 8:55 pm - 9:20 pm | Clemencia Pinilla (Torry Pines Institute of Molecular Studies)
"Advances in T cell specificity" |
| 9:20 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | DRUG DELIVERY |
| Discussion Leader: John Mayer (Eli Lily) |
| 9:00 am - 9:25 am | Tom Strack (Pfizer) |
| 9:25 am - 9:35 am | Discussion |
| 9:35 am - 10:00 am | Alessio Fasano (U Maryland) |
| 10:00 am - 10:10 am | Discussion |
| 10:10 am - 10:20 am | Poster Presentation: Tina Holm (Stockholm University)
"Cell-penetrating peptides derived from the leucine zipper interface of AP-1 for inhibition of proliferation in cancer cells" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am - 11:25 am | Eric Dadey (QLT, Inc.) |
| 11:25 am - 11:35 am | Discussion |
| 11:35 am - 12:00 pm | Edward Maggio (Aegis Therapeutics, Inc.) |
| 12:00 pm - 12:10 pm | Discussion |
| 12:10 pm - 12:20 pm | Poster Presentation: Reto Stöcklin (Atheris Laboratories)
"Pepdidomics-Assisted Drug Discovery in Animal Venoms" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | PEPTIDES TO PROTEINS |
| Discussion Leader: William Lubell (U. Montreal) |
| 7:30 pm - 7:55 pm | Armin Geyer (U. Marburg)
"The chemical challenge of synthesizing biological peptides in single conformational states" |
| 7:55 pm - 8:05 pm | Discussion |
| 8:05 pm - 8:30 pm | Annelise Barron (Northwestern)
"Amphipathic, sequence-specific peptoids as functional mimics of membrane-active peptides" |
| 8:30 pm - 8:40 pm | Discussion |
| 8:40 pm - 8:50 pm | Poster Presentation: Neal J. Zondlo (University of Delaware)
"Design of Tunable Proteins: Control of Protein Structure by Phosphorylation, by Electronics, and by Stereoelectronics" |
| 8:50 pm - 8:55 pm | Discussion |
| 8:55 pm - 9:20 pm | Floyd Romesberg (Scripps) |
| 9:20 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | PEPTIDES METABOLISM |
| Discussion Leader: Carrie Haskell-Luevano (U. Florida) |
| 9:00 am - 9:25 am | Carrie Haskell-Luevano (U. Florida)
"Structure-Function Studies of the Agouti-Related Protein: Conversion From a Melanocortin Receptor Antagonist to Agonist" |
| 9:25 am - 9:35 am | Discussion |
| 9:35 am - 10:00 am | John Mayer (Eli Lily)
"Melanocortin Agonists for Obesity" |
| 10:00 am - 10:10 am | Discussion |
| 10:10 am - 10:20 am | Poster Presentation: John M. Stewart (University of Colorado Health Science Center)
"New Bradykinin B-1 Receptor Peptide Antagonists" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:25 am | David Fry (Hoffmann-La Roche)
"Development of Rigid MC-4R Peptide Agonists to Obtain a Refined Pharmacophore Model" |
| 11:25 am - 11:35 am | Discussion |
| 11:35 am - 11:45 am | Poster Presentation: Sonia Cantel (Harvard Medical School)
"In Situ eIF4e-Templated Click Reaction - eIF4g-Derived eIF4e Binding Peptides as Anchoring Fragments in Search of Putative Exosites" |
| 11:45 am - 11:55 am | Discussion |
| 11:55 am - 12:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | DU VIGNEAUD AWARDS |
| Discussion Leader: R. Hodges (U. Colorado) |
| 7:30 pm - 8:20 pm | Samuel H. Gellman (University of Wisconsin)
"Structure and Function in Peptidic Foldamers" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:20 pm | Barbara Imperiali (Massachusetts Institute of Technology)
"Peptide and Protein Probes for the Study of Complex Biological Systems" |
| 9:20 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
