SUNDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:45 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Speakers |
| Discussion Leaders: Fred Naider (College of Staten Island) and Maria A. Bednarek (Medimmune Ltd) |
7:40 pm - 8:20 pm | Ada Yonath (Weizmann Institute of Science)
"Studies on the ultimate peptide synthesizer - structure and function of the Ribosome" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Samuel Danishefsky (Columbia U. and Sloan Kettering)
"A promising general solution to the ligation of glycopeptides" |
9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Structural Biology and Peptide Signals |
| Discussion Leader: Carrie Haskell-Luevano (U. Minnesota) |
9:00 am - 9:25 am | Ken Jacobson (NIH)
"Understanding Peptide Activated GPCRs; Lessons Learned from the Adenosine Receptor" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Ellen Chien (The University of Chicago)
"X-ray Structures of GPCRs - Application to Peptide Signals" |
10:00 am - 10:10 am | Discussion |
10:10 am | Group Photo / Coffee Break |
10:40 am - 11:05 am | Oliver Zerbe (University of Zurich)
"NMR Studies on Large Peptide Fragments of GPCRs" |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:40 am | Thomas J. McMurry (Anchor Pharmaceuticals)
"Pepducins - drugs that modulate GPCR activity" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:15 pm | Timothy Geary (McGill University)
"Antiparasitic drug discovery targeting invertebrate peptide receptors" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Membrane Peptides and Peptide Toxins |
| Discussion Leader: Charles Deber (University of Toronto Hospital for Sick Children) |
7:30 pm - 7:55 pm | Baldomero M. Olivera (University of Utah)
"Ion Channels as targets for Conotoxins" |
7:55 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Anne S. Ulrich (Karlsruhe Institute of Technology)
"Structure-function analysis of short antimicrobial peptides" |
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Shana O. Kelley (University of Toronto)
"Mitochondria-penetrating peptides" |
9:15 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Chemical Methods and Chemical Biology |
| Discussion Leader: Michael Chorev (Harvard Medical School) |
9:00 am - 9:25 am | Kent Kirshenbaum (New York University)
"Synthetic peptoid foldamers as enantioselective catalysts" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Jeffrey N. Johnston (Vanderbilt University)
"Umpolung amide synthesis" |
10:00 am - 10:10 am | Discussion |
10:10 am | Coffee Break |
10:40 am - 11:05 am | Zachary Ball (Rice University)
"Catalysis with rhodium metallopeptides" |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:40 am | Anna Mapp (University of Michigan)
"Synthetic and chemical biology approaches to peptidomimetics as transcriptional inhibitors" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:15 pm | Mark Distefano (University of Minnesota)
"Synthetic Peptide Methodology for the Study of C-terminal Protein Lipidation" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Peptide Vaccines |
| Discussion Leader: Anna Maria Papini (University of Florence) |
7:30 pm - 7:55 pm | Jacob Anglister (Weizmann Institute of Science)
"Design of constrained V3 peptides in HIV-1 vaccine development" |
7:55 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Bryce Chackerian (University of New Mexico)
"Bacteriophage Virus-like Particles: A Flexible Platform for the Development of Peptide-based Vaccines" |
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Jamie Kathleen Scott (Simon Fraser University)
"How the neutralization-competent structure of the HIV-1 MPER informs peptide vaccine design" |
9:15 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Peptides as Drug Carriers and Imaging Agents |
| Discussion Leader: Jeffrey M Becker (University of Tennessee) |
9:00 am - 9:25 am | Erkki Ruoslahti (U.C. Santa Barbara)
"Tumor-Penetrating Peptides in Targeted Chemotherapy" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Steven Dowdy (U.C. San Diego)
"Peptide Transduction Domains in Drug Delivery" |
10:00 am - 10:10 am | Discussion |
10:10 am | Coffee Break |
10:40 am - 11:05 am | Ting Xu (U.C. Berkeley)
"Long Circulating Micelles Based on Peptide-polymer Conjugates" |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:40 am | Weibo Cai (University of Wisconsin-Madison)
"Peptide-Conjugated Nanomaterials for Cancer Targeting and Imaging" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:15 pm | Abhijit Bhat (CovX Research)
"Chemical Strategies for Generating Multifunctional Biotherapeutic Reagents" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:00 pm | Chemical Synthesis and Degradation of Polypeptides |
| Discussion Leader: Phil Dawson (Scripps Research Institute) |
7:30 pm - 8:05 pm | Tom Muir (Princeton University)
"Protein Ligation: An Enabling Technology for studying Post-translational Modifications" |
8:05 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Ashraf Brik (Ben Gurion University)
"Chemical Biology with the Ubiquitin Signal" |
8:45 pm - 9:00 pm | Discussion |
9:00 pm - 9:30 pm | Roundtable Peptide Science: The Past and Future |
|
- Charles M. Deber (University of Toronto)
- Evaristo Peggion (University of Padua)
- Maurice Manning (University of Toledo)
- Michael Verlander (Polypeptides Laboratories, Inc)
|
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Structure and Function of Amyloid Polypeptides |
| Discussion Leader: James Nowick (U.C. Irvine) |
9:00 am - 9:25 am | David Eisenberg (U.C. Los Angeles)
"The Amylone: function and structure of β-amyloid proteins" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Matthew Chapman (U. Michigan)
"Structure and function of Curli fibers" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:40 am | Coffee Break |
10:40 am - 11:05 am | Aileen Susanne Funke (Dusseldorf)
"Mirror image phage display - a method to generate D-peptide ligands for use in diagnostic and therapy of Alzheimer's disease" |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:40 am | David Eliezer (Cornell Medical School)
"Structure studies on α-synuclein peptides" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:15 pm | Gonen Ashkenasy (Ben Gurion University)
"Self-assembly driven self-replication of amphiphilic peptides" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Peptides as Materials |
| Discussion Leaders: Les Miranda (Amgen) and Dek Woolfson (U Bristol) |
7:30 pm - 7:55 pm | Joel Collier (University of Chicago)
"Peptide Assemblies: From Cell Scaffolds to Immune Adjuvants" |
7:55 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Alex Kros (Leiden Institute of Chemistry)
"Amphiphilic peptides in nano science" |
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Jin Montclare (Polytechnic University)
"Engineering smarter polypeptide materials" |
9:15 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |