| Sunday, June 21 |
- 7:30-8:30 PM
Chair's Welcome, Overview, and Introductory Remarks
- 8:30-9:30 PM
Professor Henry Bourne, University of California, San Francisco
Keynote Lecture: How Receptors'Talk' to G-proteins
- 9:30 PM
Reception
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Monday, June 22
The chemokine system in hematopoietic development, leucocyte trafficking and regulation (I) |
| Discussion Leader: John Westwick, University of Bath
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- 9 AM-10:30 AM
Focus session: Short Reports - The Mechanics of Migration
- Peter Devreotes, Johns Hopkins
Spatial and temporal sensing in eukaryotic cells
- Brett Premack, UCLA
Chemokine receptor function in migrating cells: fast lanes and floppy pockets
- Henry Bourne, UCSF
Signaling mechanisms in neutrophil chemotaxis
- John Westwick, Bath
New insights into chemokine receptor distribution and function
10:30 AM - 11:00 AM, Coffee break
11:00 AM - 12:30 PM, Focus: New Chemokine Elements
- Carlos Martinez-A, Madrid
Dynamic behavior of chemokine receptors during migration
- Osamu Yoshie, Kinki University
New receptor/ligand interactions in the chemokine system
12:30 PM - Lunch
4:30-6:30 PM - Poster Session
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Chemokines and infectious disease (I): Recent advances in HIV/SIV research |
| Discussion Leader: Dan Littman, NYU
|
- 7:30-10:30 PM
- Dan Littman, NYU
Update on chemokine receptors in development and HIV disease
- Craig Gerard, Harvard
gp120/chemokine receptor interactions
- Phil Murphy, NIH
An HIV-encoded chemokine inhibitor
9:00 PM - 9:25 PM, Coffee Break
- Steve O'Brien, NCI
Chemokines, chemokine receptors, and their genes as regulators of AIDS pathogenesis
9:55 PM - 10:30 PM, 'Fast Break' Session: Emerging Debates in Chemokine - HIV Interactions
- Benhur Lee, Univ. Penn
MDC and HIV inhibition I
- Pat Gray, ICOS
MDC and HIV inhibition II
|
Tuesday, June 23
The chemokine system in hematopoietic development, leucocyte trafficking and regulation (II) |
| Discussion Leader: Dan Witt, Repligen
|
- 9:00 AM-12:30 PM
Focus Session: The Chemokine System in Th1/Th2 Biology
- Steve Kunkel, Univ. Michigan
Chemokine biology during the Th1/Th2 transition
- Antonio Lanzavecchia, Basel Institute
Chemokine receptor expression and regulation in T lymphocytes and dendritic cells
10:30 AM - 11:15 AM, Coffee break and photo
- Michael D. Gunn, UCSF
Chemokines required for the homing of lymphocytes to secondary lymphoid organs
- Christine Power, Ares Serono
CCR4 in Th1/Th2 polarization
12:30 PM - Lunch
4:30-6:30 PM - Poster Session
|
| Chemokines in dendritic cell biology, transplantation, and immunotherapy |
| Discussion Leader: Melissa Pope, Rockefeller University
|
- 7:30-9:30 PM
- Alberto Mantovani, Mario Negri, Milan
The 'weigh anchor/hoist sail' model of dendritic cell migration
- Christophe Caux, Schering Plough, France
Regulation of chemokine receptors during dendritic cell maturation
- Wayne Hancock, Leukosite
Antigen-dependent and -independent chemokine receptor and ligand induction: new approaches to transplant immunobiology
- Selected short poster presentations (two)
|
Wednesday, June 24
Chemokines in the biology of the nervous systems |
| Discussion Leader: Steve Kunkel, U. of Michigan
|
- 9:00 AM-12:30 PM
- Bill Karpus, Northwestern University
Chemokine regulation of the immune-mediated demyelinating response
- Richard Ransohoff, Cleveland Clinic
Chemokines in multiple sclerosis and related animal models: chemotaxis and more
10:30 AM - 11:00 AM, Coffee Break
- Richard Horuk, Berlex
Chemokine receptors in the CNS
- Kevin Bacon, Neurocrine
Receptor expression and cell activation in the CNS by fractalkine
12:30 PM - Lunch
4:30-6:30 PM - Poster Session
|
| Chemokines and infectious disease (II): Herpes and Pox viruses |
| Discussion Leader: Ed Mocarski, Stanford University |
- 7:30-9:30 PM
- Grant McFadden, Robarts Research Institute
Chemokines and pox viruses: the myxoma virus model
- Marvin Gershengorn, Cornell
Chemokine regulation of Kaposis Sarcoma Herpes virus GPCR function
- Tom Schall, ChemoCentryx
New lessons from Cytomegalovirus
- Thue Schwartz, Univ. Copenhagen
7TM recepterology: lessons from endogenous and virally-encoded chemokine elements
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Thursday, June 25
Advances in genetic and animal models of chemokine function in disease and development |
| Discussion Leader: Martin Lipp, Max Delbrueck Center |
- 9 AM-12:30 PM
- Barret Rollins, Dana Farber
In vivo function of MCP-1 in genetically-modified mice
- Izzy Charo, UCSF
Update on CCR2 knockout mouse: evidence for an important role in early atherosclerosis
10:40 AM - 11:00 AM, Coffee Break
- Ann Richmond, Vanderbilt
MIP-2 and murine Duffy antigen transgenics: explorations in tumerigenesis and angiogenesis
- Alison Humbles, Harvard
Update on CXCR3 and CCR3 knockouts
12:30 - Lunch
4:30-6:30 PM - Poster Session
|
| Technology advances: therapeutic developments in chemokine biology |
| Discussion Leader: Walter Newman, LeukoSite
|
- 7:30-9:30 PM
- Kurt Jarnagin, Roche Bioscience
Inhibition of MCP-1 binding and signaling by small molecule antagonists of CCR2
- Laurence Cagnon, City of Hope
Efficacy of anti-chemokine receptor ribozymes
- Tracey Handel, UC Berkeley
Mutagenesis and structure analysis of MCP-1 and its receptor: structural determination of binding site interactions
- Selected Short Poster presentations:
Emerging Chemokine Inhibitory Compounds
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| Friday, June 26 |
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