Sunday July 23 |
2:00pm-11:00 pm | Arrival and registration |
6:00 pm | Dinner |
7:30pm-8:00 pm | Introductions |
8:00-9:30 pm | KEYNOTE ADDRESS
Alan B. Ezekowitz, Harvard University
"PATTERN RECOGNITION MOLECULES IN INNATE IMMUNITY" |
Monday July 24 Session I | THE CHEMOKINE REPERTOIRE |
7:30am-8:30 am | Breakfast |
8:45-9:00 am | Gordon Conference Photo Shoot |
9:00am-12:30pm | Albert Zlotnik (Chair), DNAX Research Institute
"WHAT HAVE WE LEARNED ABOUT THE CHEMOKINE SUPERFAMILY AS IT REACHES COMPLETION?"
Osamo Yoshie, Medical Science Shionogi Institute
"EXPANDING WORLD OF IMMUNE CHEMOKINES |
10:00am-10:30am | COFFEE BREAK |
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Michael Briskin, Millennium Pharmaceuticals
"THE BONZO LIGAND IS A NOVEL PROTEIN RELATED TO THREE DIFFERENT CHEMOKINE FAMILIES"
Tom Schall, Chemocentryx
"MAPPING THE 'CHEMOKINOME': INTRINSIC BEAUTY AND PRACTICAL BENEFITS"
Amanda Proudfoot, Sorono Pharmaceutical research Institute
"PROBING THE ROLE OF THE GAG/CHEMOKINE INTERFACE"
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12:30pm-1:30 pm | Lunch |
1:30pm-4:00 pm | Free Time |
4:30pm-6:00 pm | Poster session |
6:00pm | Dinner |
Monday July 24 Session II | MECHANISM OF CHEMOKINE ACTION |
7:30 pm | John Westwick (Chair)
Carlos Martinez-A, University of Madrid
"CHEMOKINE RECEPTOR SIGNALING AND ITS IMPLICATIONS FOR CELL ADHESION AND CHEMOTAXIS"
Kevin Bacon, Bayer
"COMPLEXITIES IN FRACTALKINE-MEDIATED SIGNALING-CASCADES DIRECTED TO CYTOSKELETAL REARRANGEMENT AND CELL SURVIVAL"
Ann Richmond, Vanderbilt University
"CRUCIAL SIGNALS INVOLVED IN THE REGULATION OF CHEMOKINE RECEPTOR TRAFFICKING" |
Tuesday July 25th
Session III | CHEMOKINES IN INNATE IMMUNITY |
7:30am-8:30am | Breakfast |
9:00am-12:30pm | Marco Baggiolini (Chair)
Joost Oppenheim, NCI-Fredrick Cancer Center
"LEUKOCYTE GRANULE PRODUCTS MOBILIZE INNATE AND ADAPTIVE HOST DEFENSES"
Kouji Matsushima, University of Tokyo
"CHEMOKINE RECRUITED DENDRITIC CELLS AS MASTER CELLS LINKING INNATE AND ACQUIRED IMMUMITY"
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10:00am-10:30am | COFFEE BREAK |
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Alberto Mantovani, Mario Negri Research Institute
"TUNING AND SHAPING OF THE CHEMOKINE SYSTEM IN CELLS INVOLVED IN INNATE IMMUNITY"
Jens-Michael Schroder, University of Kiel
"CHEMOKINES, DEFENSINS AND INNATE IMMUNITY"
Donald Cook, Schering Plough Research Institute
"CCR6, DENDRITIC CELL MIGRATION AND MUCOSAL IMMUNE RESPONSES"
Wendy Peters, University of California San Francisco
"SUSCEPTIBILITY OF CCR2 -/- MICE TO MYCOBACTERIUM TUBERCULOSIS INFECTION" |
12:30pm-1:30 pm | Lunch |
1:30pm-4:00 pm | Free Time |
4:30pm-6:00 pm | Poster session |
6:00pm | Dinner |
Tuesday July 25th Session IV | CHEMOKINES IN ADAPTIVE IMMUNITY |
7:30pm-9:30pm | Andrew Luster (CHAIR)
Barrett Rollins, Harvard University
'CONTROL OF INFLAMMATORY DISEASE AND T HELPER CELL POLARIZATION BY MCP-1"
Antonio Lanzavecchia, Institute for Bioimedical Research
"REGULATION OF CHEMOKINE RECEPTORS ON EFFECTOR AND MEMORY CELLS"
Michael D. Gunn, Duke University
"THE ROLE OF T CELL COMPARTMENTALIZATION IN IMMUNE RESPONSES: LESSIONS FROM PLT MICE"
Reinhold Forster, Max Delbruck Center
"CCR7 COORDINATES THE MIGRATION OF DEFINED LYMPHOCYTES AND DENDRITIC CELL PUBPOPULATIONS" |
Wednesday July 26th Session V | CHEMOKINE BIOLOGY DURING CHRONIC DISEASE I |
7:30am-8:30am | Breakfast |
9:00am-12:30pm | Joshua Farber (Chair)
Nicholas Lukacs, University of Michigan
"SELECTIVE INDUCTION OF CHEMOKINES IN RESPIRATORY SYNCYCIAL VIRUS-MEDIATED PULMONARY DISEASE"
Jose Carlos Gutierrez-Ramos, Millennium Pharmaceutical
"SEQUENTIAL INVOLVEMENT OF CHEMOKINE RECRUITMENT OF TH-1 AND TH2 CELL IN VIVO"
Craig Gerard, Harvard University
"WHAT HAVE WE LEARNED FROM CHEMOKINE RECEPTOR KNOCKOUTS?" |
10:00-10:30 | Coffee Break |
| Israel Charo, University of California San Francisco
"MONOCYTES AND THE IMMUNE RESPONSE IN ATHEROSCLEROSIS: INSIGHTS FORM KNOCKOUT MICE"
Richard Ransohoff, Cleveland Clinic
"INFLAMMATORY DEMYELINATION OF THE HUMAN NERVOUS SYSTEM: THE CHEMOKINE CONNECTION"
Joan Berman, Albert Einstein College of Medicine
"MECHANISM OF LEUKOCYTE TRAFFICKING ACROSS THE BLOOD BRAIN BARRIER-THE ROLE OF CHEMOKINES AND ADHESION PROTEINS" |
12:30pm-1:30 pm | Lunch |
1:30pm-4:00 pm | Free Time |
4:30pm-6:00 pm | Poster session |
6:00pm | Dinner |
Wednesday July 26th SESSION VI | CHEMOKINES AND CANCER BIOLOGY |
7:30 pm | Sergio Lira (Chair), Schering Plough research Institute
"EXPRESSION OF THE CHEMOKINE RECEPTOR ENCODED BY HHV8 LEADS TO A ANGIOPROLIFERATIVE DISEASE RESEMBLING KAPOSI'S SARCOMA"
Robert Strieter, University California Los Angles
"CXC CHEMOKINES REGULATE ANGIOGENESIS IN CANCER AND CHRONIC FIBROPROLIFERATIVE DISORDERS"
Fran Balkwill, Imperial Cancer Research Fund
"INS AND OUTS OF EPITHELIAL CANCER: CHEMOKINES, LEUKOCYTE INFILTRATION AND METASTASIS"
Hal Broxmeyer, Indiana Univesity
CHEMOKINES AND HEMATOPOIESIS: NEW INSIGHTS |
Thursday July 27th Session VII | SMALL MOLECULAR WEIGHT CHEMOKINE RECEPTOR ANTAGONISTS |
7:30am-8:30am | Breakfast |
9:00am-12:30pm | Marty Springer (Chair), Merck and Company
"DEVELOPMENT OF CCR5 ANTAGONISTS: SPECIAL PROPERTIES REQUIRED FOR ANTIVIRAL ACTIVITY"
Julie Strizki, Schering Plough Research Institute
"SCH-C, A NOVEL CCR5 ANTAGONIST , IS A POTENT INHIBITOR OF HIV INFECTION"
John Moore, Aaron Diamond AIDS Research Center
"A BINDING SITE ON CCR5 FOR A SMALL MOLECULE INHIBITOR OF HIV-1 ENTRY" |
10:30am-11:00am | Coffee Break |
| Richard Horuk, Berlex Bioscience
"IDENTIFICATION OF HIGH AFFINITY, ORALLY AVAILABLE AND EFFICACIOUS CCR1 ANTAGONISTS"
John White, SmithKline Beecham Pharmaceutical Company
"IN VITRO AND IN VIVO PROPERTIES OF A SMALL MOLECULAR WEIGHT CXCR2 RECEPTOR ANTAGONIST" |
12:30-1:30 pm | Lunch |
1:30-4:00 pm | Free Time |
4:30-6:00 pm | Poster session |
6:00pm | Dinner |
Thursday July 27th Session VIII | CHEMOKINES AND CHEMOKINE RECEPTORS DURING VIRAL INFECTIONS |
7:30pm | Phil Murphy (CHAIR), National Institute of Allergy and Infectious Disease
"CHEMOKINES AND VIRAL INFECTIONS"
Robert W. Doms, University of Philadelphia
"HOW HIV INFECTION IS AFFECTED BY CHEMOKINE RECEPTOR CONFORMATION, DENSITY, AND AFFINITY FOR ENV"
Grant McFadden, John T. Roberts Research Institute
"HOW POXVIRUSES EXPLOIT CELLULAR CHEMOKINE RECEPTORS"
Christine Biron, Brown University
"CRITICAL ROLES FOR CHEMOKINES IN DEFENSE AGAINST VIRAL INFECTIONS" |
Friday July 28th |
7:30am-8:30 am | Breakfast |
9:00am | Departure
Bus leaves Conference Site |