SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 9:20 pm | KEYNOTE SESSION |
7:30 pm - 8:00 pm | Welcome and Introduction: Sergio Lira |
8:00 pm - 9:00 pm | Ron Germain (NIH) "How Chemoattractants Work: From In Silico Models to In Vivo Movies" |
9:00 pm - 9:20 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | CHEMOKINES AND DEVELOPMENT |
| Discussion Leader: Martin Lipp (MDC) |
9:00 am - 9:10 am | Discussion Leader's Introduction |
9:10 am - 9:30 am | Erez Raz (Max Planck Institute, Gottingen) "Chemokine signaling in zebrafish germ cell migration" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:00 am | Dan Littman (NYU) "Chemokines in lymphoid neogenesis" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:30 am | Martin Lipp (MDC) "Development of functional ectopic lymphoid tissues" |
10:30 am - 10:40 am | Discussion |
10:40 am - 11:00 am | Coffee Break / Group Photo |
11:00 am - 11:20 am | Fabienne Mackay (Garvan Institute) "CXCR7/RDC1 plays a specific role in the development of semi-lunar heart valve" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Robert Strieter (UCLA) "The role of Circulating Mesenchymal Stem Cells in the Pathogenesis of Pulmonary Fibrosis and Metabolic Syndrome" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:15 pm | Short Talk: Tatjana Marinkovic (Mount Sinai) "Chemokines and tertiary lymphoid organogenesis in the thyroid" |
12:15 pm - 12:30 pm | Short Talk: Troy Randall (Trudeau Institute) "Role of chemokines in the development and function of lymphoid tissues in the respiratory tract" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | CHEMOKINE DRUGS |
| Discussion Leader: Tim Wells (Serono) |
7:30 pm - 7:40 pm | Discussion Leader's Introduction |
7:40 pm - 8:00 pm | Richard Horuk (Berlex) "Chemokine receptor antagonists, promiscuous or specific, that is the question" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | Roy Gulick (Cornell) "Chemokine receptors for the treatment of HIV infection" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:00 pm | Antonio Alcami (CSIC) "Role of virus-encoded chemokine binding proteins in immune modulation and infection" |
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Carolina Abramovich (Chemokine Therapeutics) "A novel SDF-1 mimetic with strong pro-angiogenic effect" |
9:25 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | CHEMOKINES IN HOMEOSTASIS |
| Discussion Leader: Steve Kunkel (University of Michigan) |
9:00 am - 9:10 am | Discussion Leader's Introduction |
9:10 am - 9:30 am | Andy Luster (Harvard) "A chemoattractant links inflammation to fibrosis" |
9:30 am - 9:40 am | Discussion |
9:40 am – 10:00 am | Denis Klinman (FDA) "Impact of CpG oligonucleotide class on cytokine and chemokine profile" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:30 am | Marc Parmentier (Bruxelles) "Allosteric interactions in chemokine receptor dimers" |
10:30 am - 10:40 am | Discussion |
10:40 am - 11:00 am | Cofee Break |
11:00 am - 11:20 am | Antonella Viola (Humanitas) "Chemo-attraction and chemo-distraction at the immunological synapse" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Carlos Martinez-A (CNBIO) "Functional consequences of chemokine receptor homo-, hetero- and orthodimerization" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:15 pm | Short Talk: Nicole Neel (Vanderbilt) "Regulation of CXCR2 trafficking and signaling by RhoB and novel interacting proteins" |
12:15 pm - 12:30 pm | Short Talk: Haribabu Bodduluri (U. Louisville) "Regulation of dendritic cell migration by Leukotriene B4 through Up-regulation of CCR7" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | CHEMOKINES IN HOMEOSTASIS II |
| Discussion Leader: Marcus Thelen (Bellinzona) |
7:30 pm - 7:40 pm | Discussion Leader's Introduction |
7:40 pm - 8:00 pm | Laurie Glimcher (Harvard) "T-bet and Type 1 immunity" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | Reinhold Forster (Hannover) "A crucial role for CCR7 in establishing central and peripheral tolerance" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:00 pm | Izzy Charo (Gladstone Institute) "Critical roles for CCR2 and MCP-3 in monocyte egress from the bone marrow and migration to inflammed tissue" |
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Antal Rot (Novartis) "Chemokine Receptors and Interceptors in Regulating Immunity and Inflammation" |
9:25 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
9:00 am - 12:30 pm | CHEMOKINES AND DISEASE I |
| Discussion Leader: Izzy Charo (UCSF) |
9:00 am - 9:10 am | Discussion Leader's Introduction |
9:10 am - 9:30 am | Richard Ransohoff (Cleveland Clinic) "Chemokines in neurological disease: Inflammation meets neurobiology" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:00 am | George Diaz (Mount Sinai) "Chemokine receptor function and dysfunction in neutrophil trafficking defects" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:30 am | Kouji Matsushima (U. Tokyo) "Regulation of the induction and maintenance of anti-viral CTL immunity by chemokines" |
10:30 am - 10:40 am | Discussion |
10:40 am - 11:00 am | Cofee Break |
11:00 am - 11:20 am | Alberto Mantovani (Humanitas) "Tuning inflammation by chemokine decoy receptors" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Eric Pamer (Memorial Sloan-Kettering) "CCR2-mediated signaling in response to bacterial infection" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:15 pm | Short Talk: Jon Bromberg (Mount Sinai) "T cell and dendritic cell migration in transplantation tolerance" |
12:15 pm - 12:30 pm | Short Talk: Wayne Hancock (U Penn) "Chemokine-dependent Pathways Required for Allograft Rejection and Allograft Tolerance" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | CHEMOKINES IN DISEASE II |
| Discussion Leader: Albert Zlotnik (Neurocrine) |
7:30 pm - 7:40 pm | Discussion Leader's Introduction |
7:40 pm - 8:00 pm | Phil Murphy (NIH) "Defining roles for chemokine receptors in human disease" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | Barrett Rollins (Danna Farber) "The Chemokine System and Cancer" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:00 pm | Osamu Yoshie (Osaka) "Role of chemokines/chemokine receptors in virus-associated human malignancies" |
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Short Talk: Cristophe Combadiere (INSERM) "CX3CR1 and macular degeneration" |
9:25 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | IMAGING/TRAFFICKING |
| Discussion Leader: Mike Dustin (NYU) |
9:00 am - 9:10 am | Discussion Leader's Introduction |
9:10 am - 9:30 am | Jason Cyster (UCSF) "S1P, CD69 and the control of lymphocyte egress" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:00 am | John Kehrl (NIH) "Chemokine receptor signaling and lymphocyte trafficking" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:30 am | HC Reinecker (Harvard) "Chemokines in the Immune Surveillance of the Intestine" |
10:30 am - 10:40 am | Discussion |
10:40 am - 11:00 am | Cofee Break |
11:00 am - 11:20 am | Rodrigo Mora (Harvard) "Intestinal dendritic cells imprint CCR9+ IgA-secreting cells via a synergistic mechanism" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Yousuke Takahama (U. Tokushima) "Cortex-to-medulla migration of thymocytes and central tolerance" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:15 pm | Short Talk: Elizabeth Ingulli (U. Minnesota) "Self-ligand stimulation promotes CD4 T cell motility and responsiveness to antigen bearing dendritic cells in vivo" |
12:15 pm - 12:30 pm | Short Talk: Ronen Alon (Weizmann Institute) "Surface-presented CCL21 promotes sustained integrin-independent motility of T lymphocytes over dendritic cells and across extracellular matrix" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | LATE BREAKING |
| Discussion Leader: Gerry Graham (Glasgow) |
7:30 pm - 7:40 pm | Discussion Leader's Introduction |
7:40 pm - 8:00 pm | Martine Smit (Amsterdam) "Viral chemokine receptor US28 as potential oncogene" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | Martine Biard (Montpellier) "CXCR4 and autophagy" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:00 pm | Amanda Proudfoot (Serono) "Highly selective chemokine binding proteins protect blood sucking parasites from the immune response" |
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Short Talk: Glaucia Furtado (Mount Sinai) "A novel model of demyelinating encephalomyelitis induced by combined expression of CCL2 and FLT3L" |
9:25 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |