Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Atypical Chemokine Receptors
Discussion Leaders: Antal Rot (Queen Mary University of London, United Kingdom)
3:15 pm - 3:30 pm
Introduction by Discussion Leader
3:30 pm - 3:40 pm
Katharina Artinger (Centre for Microvascular Research, William Harvey Research Institute, Barts and The London School of, United Kingdom)
"Erythroid ACKR1 Expression has a Protective Effect in the Pathogenesis of Experimental Glomerulonephritis"
3:40 pm - 3:45 pm
Discussion
3:45 pm - 3:55 pm
Roman Schlimgen (Medical College of Wisconsin, United States)
"Structural Basis of Nanobody-induced ACKR3 Inhibition"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Chemokine Structure, Function and Receptor Interactions
Discussion Leader: Mette Rosenkilde (University of Copenhagen, Denmark)
5:30 pm - 5:45 pm
Introduction by Discussion Leader
5:45 pm - 5:55 pm
Sergio Pontejo (National Institute of Allergy and Infectious Diseases, United States)
"Anionic Phospholipids: A New Class of Chemokine-Binding Site Important for both Dying Cell Clearance and Antibiotic Activity by Chemokines"
5:55 pm - 6:00 pm
Discussion
6:00 pm - 6:10 pm
Robert Jefferson (École Polytechnique Fédérale de Lausanne, Switzerland)
"Computational Design of Ultrasensitive Flexible Chemokine Receptor Signaling Complexes for Enhanced Chemotaxis"
6:10 pm - 6:15 pm
Discussion
6:15 pm - 6:25 pm
Pedro Marques (KU Leuven, Belgium)
"Using a Positively-Charged CXCL9-derived Peptide that Binds DNA as Treatment for Liver Injury"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
Inês Pinheiro (University of Geneva, Switzerland)
"Does Dynamic Removal of N-terminal Post-translational Modifications Orchestrate CCR5 Desensitization?"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Helena Crijns (Rega Institute, KU Leuven, Belgium)
"Affinity and Specificity for Binding to Glycosaminoglycans can be Tuned by Adapting Peptide Length and Sequence"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
Camila Raquel Branco (UNIGE - University of Geneva, Switzerland)
"Dissecting the CCR5 Activation Process"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
Maryna Samus (Queen Mary University of London, United Kingdom)
"Accelerated Experimental Cancer Growth and Altered Tumour-host Interactions in mice with ACKR1-deficient Erythroid Cells"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Chemokines and their Receptors in Homeostasis and Inflammation
Discussion Leaders: Bernhard Moser (Cardiff University, United Kingdom)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:25 am
Robin Bartolini (University of Glasgow, United Kingdom)
"Absence of CCR2 causes inflammaging environment in the fat pad of male mice"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Seppe Cambier (Rega Institute, KU Leuven, Belgium)
"Proteolytic modification of the neutrophil-attracting chemokine CXCL8 in BAL fluids from lung transplantation and COVID-19 patients"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Julia Gutjahr (Queen Mary University, United Kingdom)
"The CXCL12-CXCR4 pathway in nucleated erythroid cells of the bone marrow regulates erythropoiesis"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Vivian Oliveira (UFMG/KU Leuven, Brazil)
"The absence of CCR2 promotes alveolar macrophage proliferation to control lung inflammation in an acute lung injury model in mice"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Laura Parma (Ludwig-Maximilians-Universität München, Germany)
"Role of the CXCL12/CXCR4 axis in atherosclerotic plaque instability"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Kyler Crawford (Medical College of Wisconsin, United States)
"Structural insights on the ‘DARC’ side of CXCL12 signaling and bone marrow metastasis"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Noor Bala (Cornell University, United States)
"Perivascular Chemokine-Rich Niches Drive Spatially Restricted T-cell Activation in Inflamed Tissues"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Tips and Tricks to Develop a Successful Career
Discussion Leader: Acacia Dishman (Medical College of Wisconsin, United States)
1:30 pm - 1:35 pm
Introduction by Discussion Leader
1:35 pm - 2:30 pm
Panel Discussion
Career Panel
Tamara Girbl (University of Wuerzburg, Germany)
Brian Volkman (Medical College of Wisconsin, United States)
Martin Stone (Monash University, Australia)
Deborah Fowell (Cornell University, United States)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
