SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
4:00 pm - 6:00 pm | Welcome Reception |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | CHROMATIN STRUCTURE AND ASSEMBLY |
| Discussion Leader: Genevieve Almouzni (Institut Curie)
"Propagation of Epigenetic States at the Level of Chromatin Assembly" |
| Yoshiro Nakatani (Dana Farber Institute) |
| Chris Woodcock (University of Massachusetts)
"Chromatin Compaction and Transcription Repression" |
| Jeff Hansen (Colorado State University)
"The Histone Terminal Domains and Chromatin Architecture: Lessons in Humility" |
| Tim Richmond (ETH Zurich)
"Nucleosome Arrays and the Structure of Chromatin" |
| Michelle Barton (M.D. Anderson Cancer Center)
"The Chromatin Profile of a Tumor Marker Gene: Repression Versus Aberrant Activation" |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Photo |
9:00 am - 12:30 pm | CHROMATIN DOMAINS AND NUCLEAR ORGANIZATION |
| Discussion Leader: Gary Felsenfeld (NIH)
"Division of Labor at Chromatin Boundaries" |
| Uli Laemmli (University of Geneva) |
| Susan Gassser (University of Geneva)
"The Why of Anchors and Chromatin Dynamics in Yeast" |
10:30 am | Coffee Break |
| Joe Reese (Penn State University)
"Ssn6-Tup1 Requires the ISW2 Complex to Position Nucleosomes in Saccharomyces Cerevisiae" |
| Xin Bi (University of Rochester)
"Blocking the Propagation of Regulatory Signals Along the Chromosome by Nucleosome-excluding Structures" |
| Ann Dean (NIH)
"Dissecting Enhancer Function Using Insulators" |
| Sergei Grigoryev (Penn State University)
"Regulation of Heterochromatin Spreading During Terminal Cell Differentiation" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session (for presenters with last names beginning with A-L) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | HISTONE VARIANTS |
| Discussion Leader: David Tremethick (John Curtin School of Medical Research)
"A Novel Interplay Between H2A.Z and HP1 Regulates Higher-Order Chromatin Folding" |
| William Bonner (NIH)
"Histone H2AX: DNA's Bodyguard" |
| Barbara Panning (University of California-San Francisco)
"Inactive X Chromosome Localization of Histone macroH2A" |
| Mitch Smith (University of Virginia)
"Elongation by RNA Polymerase II is Sensitive to the Histone Variant Composition of Chromatin" |
| Martin Gorovsky (University of Rochester)
"Studies on Tetrahymena Histones and Their Modifications" |
| Hansol Lee (Robert Wood Johnson Medical School)
"Msx1 Cooperates with Histone H1b for Inhibition of Transcription and Myogenesis" |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | HISTONE MODIFICATIONS |
| Discussion Leader: David Allis (Rockefeller University)
"Recruitment and Release of Effector Proteins to Histone Methyl-Marks"
presented by Wolfgang Fischle (Rockefeller University) |
| Orjan Wrange (Karolinska Institute)
"NF1 and Oct1 induce nucleosome positioning and preset the chromatin structure of the MMTV LTR" |
| Tony Kouzarides (University of Cambridge)
"Regulation of Transcription by Histone Deimination" |
10:30 am | Coffee Break |
| Mary Ann Osley (University of New Mexico Health Sciences Center)
"Histone H2A Phosphorylation and Chromatin Remodeling at a DNA Double Strand Break Site" |
| Michael Grunstein (University of California-Los Angeles)
"Acetylation Patterns in Gene Activity" |
| Patrick Grant (University of Virginia)
"Regulation of SAGA and SLIK Function in Health and Disease" |
| Ali Shilatiford (St. Louis University)
"A COMPASS and a GPS in Defining Histone Modifications, Transcriptional Regulation, and Human Cancer: The Coordinates of the Genome" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session (for presenters with last names beginning with A-L) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | CHROMATIN REMODELING |
| Discussion Leader: Carl Wu (NCI)
"ATP-dependent Histone Sliding and Histone Exchange by Chromatin Remodeling complexes of the SWI/SNF Family" |
| Brad Cairns (Huntsman Cancer Institute)
"Mechanism and Targeting of the Chromatin Remodeling Complex RSC" |
| Xuetong Snow Shen (M.D. Anderson Cancer Center)
"Involvement of INO80 in DNA Repair" |
| Craig Peterson (University of Massachusetts Medical School)
"SWI/SNF Complex: Nucleosome Recognition and Molecular Mechanism" |
| Tom Owen-Hughes (University of Dundee)
"Mechanisms for the Action of Snf2-Related Proteins" |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | HETEROCHROMATIN |
| Discussion Leader: Sally Elgin (Washington University)
"Chromosome Four: Targeting Heterochromatin Formation in Drosophila" |
| Shiv Grewal (NIH)
"RNAi and Heterochromatin Assembly in Fission Yeast" |
| Thomas Jenuwein (University of Vienna)
"The Indexing of Potential of Histone Lysine Methylation" |
10:30 am | Coffee Break |
| Peter Becker (University of Munchen)
"Targeting the Dosage Compensation Complex to the
Drosophila Male X Chromosome" |
| Juerg Mueller (EMBL)
"Recruitment of Polycomb Group Proteins to Target Genes" |
| Eric Selker (University of Oregon)
"Control of DNA Methylation by Methylation of Histone H3 in Neurospora" |
| Marc Gartenberg (Robert Wood Johnson Medical School)
"Pairing of Sister Chromatids by Silent Chromatin in Budding Yeast" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session (for presenters with last names beginning with M-Z) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | CHROMATIN AND DEVELOPMENT |
| Discussion Leader: Steve Henikoff (Fred Hutchinson Cancer Research Center)
"Maintenance of Active Chromatin" |
| Vince Pirrotta (University of Geneva)
"How Polycomb Complexes Silence" |
| Nicole Francis (Massachusetts General Hospital)
"Chromatin Compaction by a Polycomb Group Complex" |
| Mitzi Kuroda (Harvard Medical School)
"Targeting the X Chromosome for Dosage Compensation in Drosophila" |
| Laura O'Neill (Birmingham University)
"Changes of histone modifications along the mammalian X chromosome" |
| Jill Schumacher (University of Texas)
"Tousled Chromatin: An Aurora B Connection?" |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | PATHWAYS OF ACTIVATION |
| Discussion Leader: Gordon Hager (NIH)
"The Dynamics of Chromatin Reorganization and Gene Activation" |
| Dimitris Thanos (Columbia University)
"The Role of Chromatin Architecture in Gene-Specific Transcription" |
| Steve Triezenberg (Michigan State University)
"Histones and Coactivators During Herpes Simplex Virus Infection" |
10:30 am | Coffee Break |
| William Tansey (Cold Spring Harbor Laboratory)
"Transcriptional Control and the Ubiquitin-Proteasome System" |
| Mike Kladde (Texas A & M)
"Bidirectional Propagation of Chromatin Remodeling During Transcriptional Activation" |
| Jane Mellor (University of Oxford)
"Specialized Nucleosomes Controlling Transcription Elongation" |
| Phillipp Korber (University of Munchen)
"Chromatin in Trans-ition: Fate of Histones at the PHO5 Promoter" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session (for presenters with last names beginning with M-Z) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | SIGNALING AND TRANSCRIPTION |
| Discussion Leader: Fred Winston (Harvard Medical School)
"Analysis of Transcription and Chromatin Structure in Yeast" |
| Trevor Archer (NIH)
"Multifaceted Signaling with Nuclear Receptors and the hSWI/SNF Complex" |
| Rolf Sternglanz (Stony Brook University)
"Yeast Sir3 and Orc1 BAH Domains and Their Role in Silencing" |
| Robert Roeder (Rockefeller University)
"Disease-related Inhibition of HAT Functions" |
| Danny Reinberg (HHMI/UMDNJ) |
| Michael Carey (UCLA School of Medicine)
"Physical and Functional Interactions Between the Mediator Complex and Chromatin Modification Enzymes" |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |