| SUNDAY |
| 4:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Chromatin structure: the nucleosome and beyond |
| Discussion Leader: Karolin Luger (Colorado State University) |
| 7:30 pm - 7:50 pm | Johnathan Widom (Northwestern U)
"A Genomic Code for Nucleosome Positioning and Function" |
| 7:50 pm - 7:55 pm | Discussion |
| 7:55 pm - 8:15 pm | Tim Richmond (ETHZ)
"Pinning Down the Nucleosome Higher-Order Structure" |
| 8:15 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:40 pm | Daniela Rhodes (Cambridge)
"EM analysis of the structure of the '30nm' chromatin fibre" |
| 8:40 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:05 pm | Jeff Hansen (Colorado State Univ)
"Intrinsic disorder in histones and other nuclear proteins" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Karl Ekwall
"Surprising genome-wide roles for HDACs and the RNA pol II machinery" |
| 9:25 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Histone variants, chromatin assembly, and repair |
| Discussion leader: Mary Ann Osley (Univ. New Mexico) |
| 9:00 am - 9:20 am | Karolin Luger (Colorado St. Univ.)
"Nucleosomes and histone chaperones" |
| 9:20 am - 9:25 am | Discussion |
| 9:25 am - 9:45 am | Genevieve Almouzni (Institut Curie)
"Histone dynamics and their modifications" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:10 am | David Tremethick (Australian Natl Univ)
"H2A variants; modulators of higher-order chromatin formation" |
| 10:10 am - 10:15 am | Discussion |
| 10:15 am - 10:45 am | Coffee Break / Group Photo |
| 10:45 am - 11:05 am | Mitch Smith (Univ Virginia)
"Regulatory pathways of MYST Histone Acetyltransferases" |
| 11:05 am - 11:10 am | Discussion |
| 11:10 am - 11:30 am | Xuetong (Snow) Shen (MD Anderson Cancer Center)
"Chromatin Responses to DNA repair" |
| 11:30 am - 11:35 am | Discussion |
| 11:35 am - 11:55 am | Craig Peterson (Univ. Massachusetts)
"Roles for INO80 and SWR1 remodeling enzymes in DNA repair" |
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | Blaine Bartholomew
"Structural Model of Chromatin Remodeling" |
| 12:20 pm - 12:25 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session I |
| 5:30 pm - 7:30 pm | Dynamic Chromatin |
| Discussion Leader: Ali Shilatifard (St. Louis Univ) |
| 5:30 pm - 5:50 pm | Carl Wu (NIH)
"Histone H2AZ variant replacement mediated by the SWR1 complex" |
| 5:50 pm - 5:55 pm | Discussion |
| 5:55 pm - 6:15 pm | Brad Cairns (U. of Utah) |
| 6:15 pm - 6:20 pm | Discussion |
| 6:20 pm - 6:40 pm | Robert Kingston (Harvard Med School)
"Polycomb Proteins and the Maintenance of Repression" |
| 6:40 pm - 6:45 pm | Discussion |
| 6:45 pm - 7:05 pm | Toshio Tsukiyama (Fred Hutchinson Research Center)
"Chromatin remodeling factors are required for DNA replication under stress" |
| 7:05 pm - 7:10 pm | Discussion |
| 7:10 pm - 7:25 pm | Tom Owen Hughes
"Chromatin remodelling by SWI/SNF complexes" |
| 7:25 pm - 7:30 pm | Discussion |
| 8:00 pm | Dinner |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Histone Modifications and Signalling |
| Discussion Leader: Jane Mellor (Oxford) |
| 9:00 am - 9:20 am | David Allis (Rockefeller Univ)
"The 'marriage' between covalent and non-covalent mechanims of chromatin remodeling: Until gene activation do us part" |
| 9:20 am - 9:25 am | Discussion |
| 9:25 am - 9:45 am | Shelley Berger (Wistar Inst)
"Dynamic histone ubiquitylation and sumoylation in gene regulation" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:10 am | Tony Kouzarides (Cambridge)
"Chromatin modifications and their function" |
| 10:10 am - 10:15 am | Discussion |
| 10:15 am - 10:45 am | Coffee Break |
| 10:45 am - 11:05 am | Jerry Workman (Stowers Inst)
"Protein complexes that modify chromatin for transcription" |
| 11:05 am - 11:10 am | Discussion |
| 11:10 am - 11:30 am | Mary Ann Osley (Univ. New Mexico School of Med)
"Role of H2B ubiquitylation in transcription" |
| 11:30 am - 11:35 am | Discussion |
| 11:35 am - 11:55 am | Michael Grunstein (UCLA)
"Acetylation of the histone variant H2AZ is associated with genome wide gene activity in yeast" |
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | Yang Shi (Harvard Med School)
"Regulation of histone methylation by demethylases" |
| 12:20 pm - 12:25 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session I (continued) |
| 5:30 pm - 7:30 pm | Transcribed chromatin |
| Discussion Leader: Sarah Elgin (Washington Univ) |
| 5:30 pm - 5:50 pm | Ali Shilatifard (St. Louis University)
"Molecular Embroidery on Chromatin Mediated via Histone Methylation" |
| 5:50 pm - 5:55 pm | Discussion |
| 5:55 pm - 6:15 pm | Jane Mellor (Oxford)
"Maintenance of the integrity of the transcription unit in yeast" |
| 6:15 pm - 6:20 pm | Discussion |
| 6:20 pm - 6:40 pm | Brian Strahl (Univ. North Carolina)
"Connecting Histone Modifications with RNA Polymerase II Transcription" |
| 6:40 pm - 6:45 pm | Discussion |
| 6:45 pm - 7:05 pm | Ingrid Grummt (German Cancer Res. Center, Heidelberg)
"Intergenic transcripts regulate the epigenetic state of rRNA genes" |
| 7:05 pm - 7:10 pm | Discussion |
| 7:10 pm - 7:25 pm | Asifa Akhtar (EMBL)
"Dosage compensation: Old complex new facts" |
| 7:25 pm - 7:30 pm | Discussion |
| 8:00 pm | Dinner |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Silent Chromatin |
| Discussion Leader: Susan Gasser (Friedrich Miescher Inst) |
| 9:00 am - 9:20 am | Robin Allshire (Wellcome Trust Center, Edinburgh)
"CENP-A chromatin at fission yeast centromeres" |
| 9:20 am - 9:25 am | Discussion |
| 9:25 am - 9:45 am | Shiv Grewal (NIH)
"RNAi-mediated epigenetic control of the genome" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:10 am | Sarah Elgin (Wash U)
"Targeting Heterochromatin Formation in Drosophila melanogaster" |
| 10:10 am - 10:15 am | Discussion |
| 10:15 am - 10:45 am | Coffee Break |
| 10:45 am - 11:05 am | V. Pirotta (Rutgers Univ)
"Polycomb binding and chromatin modifications at Drosophila genomic PcG targets" |
| 11:05 am - 11:10 am | Discussion |
| 11:10 am - 11:30 am | Renato Paro (Univ. Heidelberg)
"Counteracting Polycomb silencing" |
| 11:30 am - 11:35 am | Discussion |
| 11:35 am - 11:55 am | Thomas Jenuwein (Inst. Mol. Path., Vienna)
"Removal of repressive histone lysine methylation marks in mammalian chromatin" |
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | Danesh Moazed (Harvard Med School)
"RNAi and heterochromatin" |
| 12:20 pm - 12:25 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session II |
| 5:30 pm - 5:50 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 5:50 pm - 7:30 pm | Chromosome Organization |
| Discussion Leader: Genevieve Almouzni (Institut Curie) |
| 5:55 pm - 6:15 pm | Gary Felsenfeld (NIH)
"Epigenetic Modifications at Chromatin Boundaries" |
| 6:15 pm - 6:20 pm | Discussion |
| 6:20 pm - 6:40 pm | Ann Dean (NIH)
"The human â-globin chromatin domain" |
| 6:40 pm - 6:45 pm | Discussion |
| 6:45 pm - 7:05 pm | Bryan Turner (Univ. Birmingham)
"Searching high and low for an epigenetic code" |
| 7:05 pm - 7:10 pm | Discussion |
| 7:10 pm - 7:30 pm | U. Laemmli (Univ. Geneva)
"Gene Promoters and Nuclear Structure" |
| 8:00 pm | Dinner |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Nuclear Organization |
| Discussion Leader: Brian Strahl (Univ. North Carolina) |
| 9:00 am - 9:20 am | Susan Gasser (Friedrich Miescher Inst., Basel)
"Silent chromatin structure" |
| 9:20 am - 9:25 am | Discussion |
| 9:25 am - 9:45 am | Andy Belmont (Univ. Illinois UC)
"Large-scale chromatin structure and dynamics associated with transcriptional activation" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:10 am | Wendy Bickmore (MRC, Edinburgh)
"Polarised opening of higher-order chromatin structure underlies colinear gene activation at mammalian Hox loci" |
| 10:10 am - 10:15 am | Discussion |
| 10:15 am - 10:45 am | Coffee Break |
| 10:45 am - 11:05 am | Peter Fraser (Babraham Inst, Cambridge)
"Chromatin dynamics and nuclear organization of transcription" |
| 11:05 am - 11:10 am | Discussion |
| 11:10 am - 11:30 am | Michelle Barton (MD Anderson Cancer Center)
"TGFß and p53 signaling to chromatin during liver regeneration" |
| 11:30 am - 11:35 am | Discussion |
| 11:35 am - 11:55 am | Danny Reinberg (UMDNJ)
"Chromatin and Its Impact on Gene Expression and Cellular Memory" |
| 11:55 am - 12:00 pm | Discussion |
| 12:05 pm - 12:25 pm | Yi Zhang (Univ. North Carolina)
"Identification and functional characterization of JmjC family of histone demethylases" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session II (continued) |
| 5:30 pm - 7:30 pm | Chromatin Programming in Development and Disease |
| Discussion Leader: Michelle Barton (MD Anderson Cancer Center) |
| 5:30 pm - 5:50 pm | Wolf Reik (Babrahamn Inst, Cambridge)
"Molecular mechanisms of epigenetic reprogramming in mammalian development" |
| 5:50 pm - 5:55 pm | Discussion |
| 5:55 pm - 6:15 pm | Jill Schumacher (M D Anderson Cancer Center)
"Chromosomal targets of the Aurora B kinase" |
| 6:15 pm - 6:20 pm | Discussion |
| 6:20 pm - 6:40 pm | Patrick Grant (Univ. Virginia)
"Histone Modifications and Neurodegenerative Disease" |
| 6:40 pm - 6:45 pm | Discussion |
| 6:45 pm - 7:05 pm | Louis Mahadevan
"Dynamic acetylation of all K4-methylated histone H3 in the mouse nucleus: implications for active genes" |
| 7:05 pm - 7:10 pm | Discussion |
| 7:10 pm - 7:25 pm | Wolfgang Fischle |
| 7:25 pm - 7:30 pm | Discussion |
| 8:00 pm | Dinner |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
