Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Epigenetic Reprogramming
Discussion Leader: Karolin Luger (University of Colorado Boulder, USA)
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:25 pm
Petra Hajkova (MRC London Institute of Medical Sciences, United Kingdom)
"Epigenetic Reprogramming in Mouse Development: What Have We Learnt?"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Genome Architecture and Chromosome Dynamics
Discussion Leaders: Lars Jansen (Gulbenkian Institute for Science, Portugal) and Jessica Woolnough (Harvard Medical School, USA)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
Nathan Gamarra (University of California, San Francisco, USA)
"The Nucleosomal Acidic Patch Relieves Auto-Inhibition by the ISWI Remodeler SNF2h"
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
Johanna Gassler (IMBA - Institute of Molecular Biotechnology, Austrian Academy of Sciences, Austria)
"Single-Nucleus Hi-C Reveals Cohesin-Dependent Organization of the Zygotic Genome"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Gurmeet Kaur (National Institutes of Health, USA)
"HU/IHF and Chromo-Domains: A Tangled Tale of Evolutionary Convergence and Divergence of Chromatin Proteins"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:15 pm
Hiroshi Sasaki (Wyss Institute for Biologically Inspired Engineering, Harvard University, USA)
"Tracing Chromosomes at the Nanoscale with DNA-PAINT"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Chromatin Regulation in Physiology and Disease
Discussion Leaders: Ana Pombo (Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Germany) and Jikui Song (University of California, Riverside, USA)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
Valentina Ignatova (Helmholtz Zentrum München, Germany)
"RNA Methylation in the Regulation of Cellular Metabolism"
9:30 am - 9:35 am
Discussion
9:35 am - 9:55 am
Robert Porter (University of Michigan Medical School, USA)
"A Neuron-Specific Methyl-Histone Regulatory Complex"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
Logan Blair (University of California, Davis, USA)
"Do Chromatin Changes Underlie De Novo Gene Origin?"
10:20 am - 10:25 am
Discussion
10:25 am - 10:45 am
Nicholas Gomez (Rockefeller University, USA)
"Stem Cell Reprogramming During Oncogenesis and Development"
10:45 am - 10:50 am
Discussion
10:50 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Yeast and Chromatin / Mentorship Component: The Next Chapter in Chromatin Biology
Discussion Leaders: Jorge Beira (ETH Zurich, Switzerland) and Narsis Attar (University of California, Los Angeles, USA)
1:30 pm - 1:40 pm
Chitra Mohan (Stony Brook University, USA)
"Using VivosX, a Disulfide Crosslinking Approach, to Capture Intra-Nucleosomal Interactions in Yeast and Human Cells"
1:40 pm - 1:45 pm
Discussion
1:45 pm - 1:55 pm
David Truong (NYU Langone Health, USA)
"Towards Total Conversion of Yeast-to-Human Chromatin Architecture"
1:55 pm - 2:00 pm
Discussion
2:00 pm - 2:30 pm
Panel Discussion
The Next Chapter in Chromatin Biology
Petra Hajkova (MRC London Institute of Medical Sciences, United Kingdom)
Lars Jansen (Gulbenkian Institute for Science, Portugal)
Karolin Luger (University of Colorado Boulder, USA)
Maria Claudia Montefusco (Elsevier, USA)
Ana Pombo (Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Germany)
Jikui Song (University of California, Riverside, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes