Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Keynote Session: Novel Approaches Investigating the Structural Role of Chromatin in Epigenetics and Disease
Discussion Leader: Jumana AlHaj Abed (Harvard Medical School, United States)
3:15 pm - 3:55 pm
Marc Marti-Renom (CNAG-CRG, Spain)
"Structure Determination of Genomes and Genomic Domains by Satisfaction of Spatial Restraints"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Peering Into 3D Architecture of the DNA in the Nucleus
Discussion Leaders: Geeta Narlikar (University of California, San Francisco, United States) and Emma Chory (Massachusetts Insitute of Technology, United States)
5:30 pm - 5:45 pm
Mark Pownall (Yale University School of Medicine, Genetics Department, United States)
"Visualizing the Organization of Transcription and Chromatin with Nucleosomal Resolution"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
Michele Gabriele (Massachusetts Institute Of Technology, United States)
"Dynamics of CTCF and Cohesin Mediated Chromatin Looping Revealed by Live-Cell Imaging"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
Stefan Niekamp (Massachusetts General Hospital & Harvard Medical School, United States)
"Phase Separation of Polycomb-Repressive Complex 1 is Promoted by a Chromatin Scaffold"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Anna Malkowska (University of Cambridge, United Kingdom)
"Profiling Chromatin States in Drosophila Melanogaster Quiescent Neural Stem Cells"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Thomas Stormberg (University of Nebraska Medical Center, United States)
"Discovery of Nucleosome Unraveling by Transcription Factor NF-kB: AFM Studies"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Sarah Faulkner (Memorial Sloan Kettering Cancer Center, United States)
"H1 Protects Stalled Replication Forks by Liquid-Liquid Phase Separation with Single-Stranded DNA"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Nucleosome Dynamics in Epigenetic States and Diseases
Discussion Leaders: Asifa Akhtar (Max Planck Institute of Immunobiology and Epigenetics, Germany) and Liyun Miao (Yale University, United States)
9:00 am - 9:10 am
Tanja Bhuiyan (University of Freiburg, Germany)
"TAF2 Condensation in Nuclear Speckles Affects RNA Polymerase II Promoters"
9:10 am - 9:15 am
Discussion
9:30 am - 9:40 am
Megan Frederick (University of Pennsylvania, United States)
"Pioneer Factor Binding Within Compacted Chromatin is Required to Enable SWI/SNF Remodeling"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Noa Furth (Weizmann Institute of Science, Israel)
"The Combinatorial Epigenome of H3-K27M Pediatric Gliomas in Single-Molecule Resolution"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Yolanda Moyano Rodriguez (Institut de Génétique Moléculaire de Montpellier , France)
"Analysis of X-Chromosome Reactivation Determinants in Female Primordial Germ Cells"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Ranya Virk (Northwestern University, United States)
"Leveraging Chromatin Packing to Modulate Phenotypic Plasticity and Chemoevasion Potential of Cancer Cells"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Liyun Miao (Yale University, United States)
"Mechanisms of Chromatin Remodeling and Genome Activation by Pioneer Factors During In Vivo Reprogramming"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Neha Bokil (MIT/Whitehead, United States)
"Sex Chromosome-Driven Regulation of Chromatin Structure"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
11:00 am - 11:15 am
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Managing up and Strategic Planning While Navigating Your Scientific Career
Discussion Leader: Robert Porter (University of Michigan Medical School, United States)
1:30 pm - 1:45 pm
Melike Lakadamyali (University of Pennsylvania, United States)
"Navigating and Managing Scientific Careers in Academia"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Carl Ebeling (Recursion Pharma, United States)
"Navigating Scientific Careers in Industry"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Carolina Perdigoto (Nature Research, United Kingdom)
"Transitioning from Academia into an Editorial Scientific Career"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes