| SUNDAY | 
| 4:00 pm - 8:00 pm | Arrival and Check-in | 
| 6:00 pm | Dinner | 
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff | 
| 7:40 pm - 9:30 pm | Chromosome Dynamics: From nucleotides to chromosomes | 
 | Discussion Leader: Julie Cooper (Cancer Research UK Lincoln's Inn Fields Laboratories) | 
| 7:40 pm - 8:30 pm	 | Keynote Lecture: Tomas Lindahl (Cancer Research UK Clare Hall Laboratories)  
"Intrinsic DNA damage and degradation of ssDNA in mammalian cell nuclei" | 
| 8:30 pm - 8:40 pm	 | Discussion | 
| 8:40 pm - 9:20 pm	 | John Marko (Northwestern University, Chicago)   
"Micromechanical analysis of chromosome-folding proteins and of whole chromosomes" | 
| 9:20 pm - 9:30 pm	 | Discussion | 
| MONDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | Views of Chromosomes | 
 | Discussion Leader: James Berger (University of California, Berkeley) | 
| 9:00 am - 9:20 am	 | James Berger (University of California, Berkeley)  
"How far does the rabbit hole go: plumbing the depths of molecular control in a DNA disentangling machine (and not hitting bottom)" | 
| 9:20 am - 9:30 am	 | Discussion | 
| 9:30 am - 9:50 am	 | Steve Harrison (Harvard Medical School)  
"Molecular architecture of kinetochores | 
| 9:50 am - 10:00 am	 | Discussion | 
| 10:00 am - 10:10 am	 | Kazuhiro Maeshima (National Institute of Genetics, Mishima)  
"Local structural similarity between interphase chromatin and mitotic chromosomes in living mammalian cells" | 
| 10:10 am - 10:15 am	 | Discussion | 
| 10:15 am		 | Group Photo / Coffee Break | 
| 10:45 am - 11:05 am	 | Barbara Funnell (University of Toronto)  
"P1 ParA and plasmid dynamics on the bacterial nucleoid" | 
| 11:05 am - 11:15 am	 | Discussion | 
| 11:15 am - 11:35 am	 | Tatsuya Hirano (RIKEN Advanced Science Institute)  
"Functional dissection of condensin I by using recombinant subunits" | 
| 11:35 am - 11:45 am	 | Discussion | 
| 11:45 am - 12:05 pm	 | Peter Fraser (Babraham Institute, Cambridge)  
"Single cell analysis of chromosome structure" | 
| 12:05 pm - 12:15 pm	 | Discussion | 
| 12:15 pm - 12:25 pm	 | Damien Hudson (Murdoch Childrens Research Institute, Australia)  
"Genome-wide map and analysis of condensin I binding sites in vertebrates" | 
| 12:25 pm - 12:30 pm	 | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 5:30 pm | Poster Session | 
| 5:30 pm - 7:30 pm | Chromosome Interactions | 
 | Discussion Leader: Abby Dernburg (University of California, Berkeley) | 
| 5:30 pm - 5:50 pm	 | Abby Dernburg (University of California, Berkeley)
 "Feedback regulation of chromosome transactions during meiotic prophase" | 
| 5:50 pm - 6:00 pm	 | Discussion | 
| 6:00 pm - 6:20 pm	 | Yasushi Hiraoka (Osaka University)  
"Inner nuclear membrane proteins that affect chromosome dynamics in fission yeast" | 
| 6:20 pm - 6:30 pm	 | Discussion | 
| 6:30 pm - 6:50 pm	 | Nancy Kleckner (Harvard University)  
"Chromosome dynamics: from meiotic chromosomes to mitotic chromosomes by way of E.coli" | 
| 6:50 pm - 7:00 pm	 | Discussion | 
| 7:00 pm - 7:10 pm	 | Xindan Wang (Harvard Medical School)  
"Bacillus subtilis chromosome organization alternates between two distinct patterns" | 
| 7:10 pm - 7:15 pm	 | Discussion | 
| 7:15 pm - 7:25 pm	 | Kimberly Collins (Stowers Institute)  
"Corolla encodes a central element protein within the Drosophila synaptonemal complex" | 
| 7:25 pm - 7:30 pm	 | Discussion | 
| 8:00 pm | Dinner | 
| TUESDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | Genome Structure and Evolution | 
 | Discussion Leader: David Sherratt (University of Oxford) | 
| 9:00 am - 9:20 am	 | David Sherratt (University of Oxford)  
"Architecture of the Escherichia coli SMC complex, MukBEF, and its action in chromosome segregation" | 
| 9:20 am - 9:30 am	 | Discussion | 
| 9:30 am - 9:50 am	 | Daniela Barilla (University of York)  
"Life pushed to extremes: genome segregation in archaea" | 
| 9:50 am - 10:00 am	 | Discussion | 
| 10:00 am - 10:10 am	 | Ann Kirchmaier (Purdue University)  
"Epigenetic profiling at single cell and single molecule resolution" | 
| 10:10 am - 10:15 am	 | Discussion | 
| 10:15 am		 | Coffee Break | 
| 10:45 am - 11:05 am	 | Bas van Steensel (NKI Amsterdam)  
"Probing chromatin position effects in high-throughput mode" | 
| 11:05 am - 11:15 am	 | Discussion | 
| 11:15 am - 11:35 am	 | Nick Luscombe (University College London)  
"Computational analyses of nuclear organisation and gene expression" | 
| 11:35 am - 11:45 am	 | Discussion | 
| 11:45 am - 11:55 am	 | Frederic Boccard (CNRS-CGM, Gif-sur-Yvette)  
"Structuring the Ter macrodomain of the E. coli chromosome: mechanisms and consequences" | 
| 11:55 am - 12:00 pm	 | Discussion | 
| 12:00 pm - 12:10 pm	 | Makkuni Jayaram (University of Texas, Austin)  
"Germ line propagation of a selfish DNA element by engaging a meiotic motor system and motor associated telomeres" | 
| 12:10 pm - 12:15 pm	 | Discussion | 
| 12:15 pm - 12:25 pm	 | Sarah Zanders (Fred Hutchinson Cancer Research Center)  
"How to cheat at sex and win: meiotic drive in fission yeast" | 
| 12:25 pm - 12:30 pm	 | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 5:30 pm | Poster Session | 
| 5:30 pm - 7:30 pm | Chromosome Architecture | 
 | Discussion Leader: John Marko (Northwestern University, Chicago) | 
| 5:30 pm - 5:50 pm	 | Edith Heard (Institut Curie, Paris)  
"Dynamic changes in chromosome structure and chromatin content during X inactivation" | 
| 5:50 pm - 6:00 pm	 | Discussion | 
| 6:00 pm - 6:20 pm	 | Olivier Espeli (CNRS Centre de Génétique Moléculaire, Gif-sur-Yvette)  
"Control of sister chromatid cohesion in E. coli" | 
| 6:20 pm - 6:30 pm	 | Discussion | 
| 6:30 pm - 6:50 pm	 | Yves Barral (ETH Zurich)  
"Partitioning DNA circles away from bona fide chromosomes" | 
| 6:50 pm - 7:00 pm	 | Discussion | 
| 7:00 pm - 7:10 pm	 | Remus Dame (Leiden University)  
"Unravelling the role of chromatin proteins in archaeal nucleoid organization" | 
| 7:10 pm - 7:15 pm	 | Discussion | 
| 7:15 pm - 7:25 pm	 | James Taylor (University of Bristol)  
"Interactions between the SMC-complex, Spo0J and DNA" | 
| 7:25 pm - 7:30 pm	 | Discussion | 
| 8:00 pm | Dinner | 
| WEDNESDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | Chromosome Replication | 
 | Discussion Leader: Sue Lovett (Brandeis University) | 
| 9:00 am - 9:20 am	 | Sue Lovett (Brandeis University)  
"Bacterial chromosome compaction and dynamics" | 
| 9:20 am - 9:30 am	 | Discussion | 
| 9:30 am - 9:50 am	 | John Diffley (Cancer Research UK Clare Hall Laboratories)  
"Mechanism of DNA replication origin licensing" | 
| 9:50 am - 10:00 am	 | Discussion | 
| 10:00 am - 10:10 am	 | Jorge Schvartzman (Centro de Investigaciones Biologicas, Madrid)  
"Topoisomerases are dispensable for the replication and segregation of yeast artificial chromosomes (YACs)" | 
| 10:10 am - 10:15 am	 | Discussion | 
| 10:15 am		 | Coffee Break | 
| 10:45 am - 11:05 am	 | Pat Higgins (University of Alabama Medical School)  
"Mechanism of linkage between rates of type-2 topoisomerase turnover and transcription elongation" | 
| 11:05 am - 11:15 am	 | Discussion | 
| 11:15 am - 11:35 am	 | Kirsten Skarstad (University of Oslo)  
"Organization of newly synthesized DNA in Escherichia coli" | 
| 11:35 am - 11:45 am	 | Discussion | 
| 11:45 am - 12:05 pm	 | Vincent Croquette (Ecole Normale Superieure, Paris)  
"Single-molecule study of the T4 replisome and its rescue by fork reversion mediated by UvsW" | 
| 12:05 pm - 12:15 pm	 | Discussion | 
| 12:15 pm - 12:25 pm	 | Karl Duderstadt (University of Groningen)  
"Single replication machines at work: the coordination of daughter strand synthesis" | 
| 12:25 pm - 12:30 pm	 | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 5:30 pm | Poster Session | 
| 5:30 pm - 7:30 pm | Chromosome Repair and Recombination | 
 | Discussion Leader: David Rudner (Harvard Medical School) | 
| 5:30 pm - 5:50 pm	 | Graham Walker (Massachusetts Institute of Technology)  
"Translesion DNA polymerases: From chemotherapy to bactericidal antibiotics" | 
| 5:50 pm - 6:00 pm	 | Discussion | 
| 6:00 pm - 6:20 pm	 | Karl-Peter Hopfner (University of Munich)  
"Structural mechanisms of DNA double-strand break repair enzymes" | 
| 6:20 pm - 6:30 pm	 | Discussion | 
| 6:30 pm - 6:50 pm	 | Scott Keeney (Memorial Sloan-Kettering Cancer Center)  
"Mechanism and regulation of meiotic recombination initiation" | 
| 6:50 pm - 7:00 pm	 | Discussion | 
| 7:00 pm - 7:10 pm	 | Kerstin Bystricky (University of Toulouse)  
"Early steps of double-strand break processing revealed by non-intrusive imaging of DNA loci in living cells" | 
| 7:10 pm - 7:15 pm	 | Discussion | 
| 7:15 pm - 7:25 pm	 | Emanuelle Fabre (Institut Pasteur)  
"Effect of nuclear architecture on the efficiency of double-strand break repair" | 
| 7:25 pm - 7:30 pm	 | Discussion | 
| 7:30 pm - 8:00 pm | Business Meeting | 
 | Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair | 
| 8:00 pm | Dinner | 
| THURSDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | Chromosome Segregation | 
 | Discussion Leader: Rebecca Heald (University of California, Berkeley) | 
| 9:00 am - 9:20 am	 | Rebecca Heald (University of California, Berkeley)  
"Investigating mitotic chromosome size and dynamics in Xenopus" | 
| 9:20 am - 9:30 am	 | Discussion | 
| 9:30 am - 9:50 am	 | Jef Boeke (Johns Hopkins University)  
"Synthesizing and scrambling yeast chromosomes" | 
| 9:50 am - 10:00 am	 | Discussion | 
| 10:00 am - 10:10 am	 | Christian Haering (EMBL, Heidelberg)  
"Topological linkage by condensin rings prevents chromosome breakage" | 
| 10:10 am - 10:15 am	 | Discussion | 
| 10:15 am		 | Coffee Break | 
| 10:45 am - 11:05 am	 | Jan Loewe (MRC Laboratory of Molecular Biology, Cambridge)  
"Bacterial plasmid segregation mechanisms" | 
| 11:05 am - 11:15 am	 | Discussion | 
| 11:15 am - 11:35 am	 | Jeff Errington (University of Newcastle)  
"Chromosome dynamics and the spatial regulation of cell division in B. subtilis" | 
| 11:35 am - 11:45 am	 | Discussion | 
| 11:45 am - 11:55 am	 | Stephan Gruber (Max Planck Institute of Biochemistry, Martinsried)  
"Architecture of a prototype SMC-kleisin complex: Smc-ScpA-ScpB" | 
| 11:55 am - 12:00 pm	 | Discussion | 
| 12:00 pm - 12:20 pm	 | Ginger Zakian (Princeton University)
 "Preventing de novo telomere addition: helicases to the rescue" | 
| 12:20 pm - 12:30 pm	 | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 5:30 pm | Poster Session | 
| 5:30 pm - 7:30 pm | Centromeres and Telomeres | 
 | Discussion Leader: Aaron Straight (Stanford University) | 
| 5:30 pm - 5:50 pm	 | Julie Cooper (Cancer Research UK Lincoln's Inn Fields Laboratories)  
"Telomeres and nuclear microenvironments: surprising means and ends" | 
| 5:50 pm - 6:00 pm	 | Discussion | 
| 6:00 pm - 6:10 pm	 | Francois Cornet (CNRS, Toulouse)
 "Active segregation of chromosome ends in bacteria"
 | 
| 6:10 pm - 6:15 pm	 | Discussion | 
| 6:15 pm - 6:25 pm	 | Stephane Marcand (CEA, Fontenay-aux-Roses)
 "Dicentric chromosomes breakage at centromeres"
 | 
| 6:25 pm - 6:30 pm	 | Discussion | 
| 6:30 pm - 6:50 pm	 | Aaron Straight (Stanford University)  
"Chromatin specialization and the assembly of metazoan centromeres" | 
| 6:50 pm - 7:00 pm	 | Discussion | 
| 7:00 pm - 7:10 pm	 | Joseph Loparo (Harvard Medical School)  
"The Bacillus subtilis ParB protein Spo0J spreads by trapping DNA loops" | 
| 7:10 pm - 7:15 pm	 | Discussion | 
| 7:15 pm - 7:25 pm	 | Anthony Vecchiarelli (NIDDK, National Institutes of Health)
 "Surfing the Bacterial Nucleoid: A key role for Spatial Confinement in ParA-mediated Partition and Transport" | 
| 7:25 pm - 7:30 pm	 | Discussion | 
| 8:00 pm | Dinner | 
| FRIDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am | Departure |