Sunday |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Session: Chromosome Dynamics: From Nucleotides to Chromosomes |
| Discussion Leader: Virginia Zakian (Princeton University, USA) |
7:40 pm - 8:10 pm | Frank Uhlmann (The Francis Crick Institute, United Kingdom) "From Chromatin to Chromosomes" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Jeanne Lawrence (University of Massachusetts Medical School, USA) "Bridging X-Chromosome Regulation to Chromosome
Pathology: New Insights into the Epigenome" |
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Michael Laub (Massachusetts Institute of Technology, USA) "Chromosome Structure and Organization in Caulobacter
crescentus" |
9:20 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Views of Chromosomes |
| Discussion Leader: Dhruba Chattoraj (National Institutes of Health, USA) |
9:00 am - 9:20 am | Sue Biggins (Fred Hutchinson Cancer Research Center, USA) "Deciphering How Tension Stabilizes Kinetochore-Microtubule Interactions" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:40 am | Selected from Poster Abstracts: Alexandra Zidovska (New York University, USA) "Mechanism and Function of Chromatin Positional Dynamics in Interphase" |
9:40 am - 9:45 am | Discussion |
9:45 am - 9:55 am | Selected from Poster Abstracts: Andrew Lane (University of California, Berkeley, USA) "Live Imaging of Non-Repetitive Chromosomal Loci Using Enzymatically Generated CRISPR Imaging Libraries" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Terumi Kohwi-Shigematsu (Lawrence Berkeley National Laboratory, USA) "Genome Organizers Drive Changing Cell Functions:
A Perspective from Stem Cells and Cancer" |
10:20 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Group Photo / Coffee Break |
11:00 am - 11:20 am | Francois Cornet (CNRS / University of Toulouse, France) "The MatP Chromosome Structuring Protein Controls Cell Division via Nucleoid Occlusion" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Selected from Poster Abstracts: Kerry Bloom (University of North Carolina, USA) "Centromere DNA Loops Generate Tension Between Sister Kinetochores in Mitosis" |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Selected from Poster Abstracts: Adam Rudner (University of Ottawa, Canada) "Cdk1 Phosphorylation of Separase Functions with PP2A and Slk19 to Regulate Pericentric Cohesin Localization and Anaphase Onset in Budding Yeast" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Anne Villeneuve (Stanford University, USA) "Dynamics of Meiotic Prophase Chromosome Structures" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Genome Structure and
Evolution |
| Discussion Leader: Aaron Straight (Stanford University Medical School, USA) |
7:30 pm - 7:50 pm | Douglas Koshland (University of California, Berkeley, USA) "The Unexpected Behaviors of Cohesin" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Houra Merrikh (University of Washington, USA) "In Vivo Visualization of Replication-Transcription Conflicts Reveals Pervasive Replisome Instability" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:40 pm | Selected from Poster Abstracts: Karine Dubrana (CEA / INSERM IRCM, France) "Nuclear Organization and Chromatin Modulate Homologous Recombination Efficiency" |
8:40 pm - 8:45 pm | Discussion |
8:45 pm - 8:55 pm | Selected from Poster Abstracts: Andrei Kuzminov (University of Illinois at Urbana-Champaign, USA) "The Dangers and Survival of the Increased Replication Complexity of the Chromosome" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | David Pellman (Dana-Farber Cancer Institute, USA) "Chromothripsis from DNA Damage in Micronuclei" |
9:20 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Chromosome Interactions |
| Discussion Leader: Abby Dernburg (Howard Hughes Medical Institute / University of California, Berkeley, USA) |
9:00 am - 9:20 am | Geeta Narlikar (University of California, San Francisco, USA) "Mechanistic Analysis of Chromatin Remodeling Motors" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Richard Gourse (University of Wisconsin, Madison, USA) "Co-Localization of Distantly Spaced Parts of the
E. coli Chromosome: A Bacterial Nucleolus" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Marc Gartenberg (Robert Wood Johnson Medical School, Rutgers University, USA) "tRNA Synthesis at Nuclear Pores: Gene Gating for RNA Polymerase III?" |
10:20 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:20 am | Suckjoon Jun (University of California, San Diego, USA) "Bacterial Chromosomes Under All (from Slow to
Fast) Growth Conditions" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Selected from Poster Abstracts: Ofer Rog (University of California, Berkeley / Howard Hughes Medical Institute, USA) "The Meiotic Synaptonemal Complex Is a Liquid Crystal" |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Selected from Poster Abstracts: Xindan Wang (Harvard Medical School, USA) "Condensin Resolves Chromosomes by Juxtaposing DNA Flanking Its Recruitment Site" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | David Shechter (Albert Einstein College of Medicine, USA) "Histone Chaperone Acidic Patch Accessibility
Regulates Chromatin Assembly" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Chromosome Repair and
Recombination |
| Discussion Leader: Barbara Funnell (University of Toronto, Canada) |
7:30 pm - 7:50 pm | Daniel Durocher (Lunenfeld-Tananbaum Research Institute, Canada) "Cell Cycle Regulation of DNA Double-Strand Break Repair" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Susan Lovett (Brandeis University, USA) "Replication Gap Repair and Template-Switching" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:40 pm | Selected from Poster Abstracts: Joseph Loparo (Harvard Medical School, USA) "Bridging the Gap: Single-Molecule Studies of Non-Homologous End Joining" |
8:40 pm - 8:45 pm | Discussion |
8:45 pm - 8:55 pm | Selected from Poster Abstracts: Olivier Espeli (College de France - CIRB, France) "Sister Chromatid Cohesion During Genotoxic Stress in E. coli" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Lorraine Symington (Columbia University, USA) "RPA and Sae2 Collaborate to Prevent Palindromic Gene Amplification" |
9:20 pm - 9:30 pm | Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Chromosome Architecture |
| Discussion Leader: John Marko (Northwestern University, USA) |
9:00 am - 9:20 am | Toshio Tsukiyama (Fred Hutchinson Cancer Research Center, USA) "Global Re-Localization of Lysine Deacetylase Drives Quiescence Entry and Maintenance" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Frederic Boccard (Integrative Cell Biology Institute, France) "Conformation and Segregation of the Chromosome
in E. coli and Pseudomonas aeruginosa" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Asifa Akhtar (Max Planck Institute of Immunobiology and Epigenetics, Germany) "Epigenetic Regulation by MOF Containing Complexes" |
10:20 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:20 am | Jeff Errington (Newcastle University, United Kingdom) "Chromosome Segregation in Sporulating Cells and L-Forms of B. subtilis" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Selected from Poster Abstracts: Daniela Garcia (Princeton University, USA) "Proteomics of Budding Yeast Telomerase: The Telomerase Associated Pop Proteins Regulate the Abundance of Telomerase RNA and Telomere Length" |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Selected from Poster Abstracts: Charles Limouse (Stanford University, USA) "Measuring Mesoscale Dynamics of Chromatin with Single-Molecule Tracking Fluorescence Correlation Spectroscopy" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Hironori Funabiki (Rockefeller University, USA) "A Proteomic View of Interactions and Dependencies on Chromatin" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Chromosome Replication |
| Discussion Leader: Scott Keeney (Howard Hughes Medical Institute / Memorial Sloan Kettering Cancer Center, USA) |
7:30 pm - 7:50 pm | Mike O'Donnell (Rockfeller University, USA) "The Structure and Function of the Eukaryotic Replisome" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Steve Bell (Indiana University, USA) "DNA Replication in the Archaea" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:40 pm | Selected from Poster Abstracts: Manuel Mendoza (Center for Genomic Regulation (CRG), Spain) "The Aurora-B Dependent NoCut Checkpoint Prevents Damage of Anaphase Bridges After DNA Replication Stress" |
8:40 pm - 8:45 pm | Discussion |
8:45 pm - 8:55 pm | Selected from Poster Abstracts: Kevin Corbett (University of California, San Diego / Ludwig Institute for Cancer Research, USA) "Regulation of the Spindle Assembly Checkpoint by the Conserved Pch2/TRIP13 ATPase" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | James Berger (Johns Hopkins University, USA) "Running Rings and Spirals Around DNA: Mechanisms
for Initiating DNA Replication" |
9:20 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Chromosome Segregation |
| Discussion Leader: Ting Wu (Harvard Medical School, USA) |
9:00 am - 9:20 am | David Sherratt (Oxford University, United Kingdom) "Coordinated Action of TopoIV and the SMC Complex, MukBEF, in E. coli Chromosome Segregation" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Christof Osman (University of California, San Francisco, USA) "Integrity of the Yeast Mitochondrial Genome, but Not Its Distribution and Inheritance, Relies on Mitochondrial Fission and Fusion" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Melissa Gardner (University of Minnesota, USA) "Dissecting the Role of Chromosome
Forces in Mitosis" |
10:20 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:20 am | Daniela Barilla (University of York, United Kingdom) "Borrowing Building Blocks
from Bacteria and Eukarya: A Three-Component DNA Segregation Machine in Archaea" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Selected from Poster Abstracts: Needhi Bhalla (University of California Santa Cruz, USA) "A Tale of Two Checkpoints" |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Selected from Poster Abstracts: Jaan Mannik (University of Tennessee, USA) "E. coli Is Capable of Translocating Its Chromosome Across Closing Division Septum" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Angelika Amon (Howard Hughes Medical Institute / Massachusetts Institute of Technology, USA) "Translational Control by an Amyloid Is Essential
for Establishing the Meiotic Chromosome Segregation Pattern" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Centromeres and Telomeres |
| Discussion Leader: Patrick Higgins (University of Alabama Medical School, USA) |
7:30 pm - 7:50 pm | Beth Sullivan (Duke University, USA) "Centromeric Plasticity on Endogenous Human Chromosomes" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Christine Jacobs-Wagner (Yale University, USA) "Spindle-Less DNA Segregation" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:40 pm | Selected from Poster Abstracts: Fei Li (New York University, USA) "Ccp1 Homodimer Mediates Chromatin Integrity by Antagonizing CENP-A Loading" |
8:40 pm - 8:45 pm | Discussion |
8:45 pm - 8:55 pm | Selected from Poster Abstracts: Julie Cooper (National Cancer Institute, NIH, USA) "Chromatin Identity Crisis: Centromeres Impersonating Telomeres, in Meiosis and Mitosis" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Agnel Sfeir (New York University Langone Medical Center, USA) "Functional Analysis of Mammalian Polθ Reveals Its Role in Double-Strand Break Repair" |
9:20 pm - 9:30 pm | Discussion |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |