Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Diverse Views of Chromosome Biology
7:40 pm - 7:45 pm
Opening Remarks
7:45 pm - 8:10 pm
"Condensin-Based
Chromosome Organization"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"Chromosome Segregation in Archaea: A Thermophilic Menage a Trois"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Imaging the Three-Dimensional Genome Organization in
Single Cells"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Interplay Between Chromosome Segregation, Replication and Cell Division in Pseudomonas aeruginosa "
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Regulation
of Transcription and Replication by Nucleoid-Associated Proteins"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Global
Chromosome Dynamics from Bacteria to Mammalian Cells"
10:20 am - 10:30 am
Discussion
10:30 am - 10:40 am
"Actively Transcribed rRNA Genes Contribute to Nucleoid Resolution in Bacillus subtilis Due to Binding of the Smc-ScpAB Condensin Complex"
10:40 am - 10:45 am
Discussion
10:45 am - 11:15 am
Coffee Break
11:15 am - 11:35 am
"Chromosome Unfolding and Gene
Regulation by Distant Enhancers"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Intracellular Long-Range Communication and Chromosomal Positioning Mechanisms in Cell Division"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Cell-Specific Long-Range Low-Frequency Interactions Regulate the Higher-Order Architecture of the Drosophila Genome"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Centromeres, Telomeres and Chromosome Stability
6:00 pm - 6:20 pm
"Noncanonical Roles of Telomeres and Centromeres in Controlling the Cell Cycle"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"Single-Molecule Experiments to Resolve Structural and Mechanical Properties of Condensin"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 7:05 pm
"Preventing Chromosome Instability: Molecular
Mechanisms of Mitotic Error correction"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Mechanisms to Maintain Centromere Stability in Human Cells"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"TZAP: A Novel Telomere-Associated Protein Involved in Telomere Length Control"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"The Dynamics of ParA-DNA and ParA-ParB Interactions During P1 Plasmid Partition"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Mechanical Architecture and Function
of the Mammalian Spindle"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Coordination of Replication and
Division Cycles"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Phase-Separation
Behavior of Heterochromatin Suggests New Avenues for Cancer Therapeutics"
10:20 am - 10:30 am
Discussion
10:30 am - 10:40 am
"Chromatin Is a Major Determinant of Nuclear Mechanics and Morphology"
10:40 am - 10:45 am
Discussion
10:45 am - 11:15 am
Coffee Break
11:15 am - 11:35 am
"Modeling Replication
Conflicts and Segregation Dynamics"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Chromosome Dynamics Probed by Single-Molecule Enzymology and Single-Cell Genomics"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Structure of Full-Length Smc and Rearrangements Required for Chromosome Organization"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Genome Structure and Dynamics
6:00 pm - 6:20 pm
"Replication-Transcription
Conflicts"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"The
Nature of Mutations Induced by Replication-Transcription Conflict"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Role
of Chromosome Structure in the Regulation of X-Chromosome-Wide Gene Expression"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Replication Stress Restricts Ribosomal DNA Copy Number"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Direct Imaging of the Circular Chromosome in E. coli "
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Chromosome Dynamics and Cancer
9:00 am - 9:20 am
"Folding
and Segregating Chromosomes: Implications for Genome Stability and Epigenetic Inheritance"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Is Heterochromatin Just a Phase?"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Regulation of the Mitotic Chromosome Surface During Nuclear Assembly"
10:20 am - 10:30 am
Discussion
10:30 am - 10:40 am
"Sizing Up the Spindle Checkpoint"
10:40 am - 10:45 am
Discussion
10:45 am - 11:15 am
Coffee Break
11:15 am - 11:35 am
"Non-Canonical Mechanisms that Detect and Respond to Errors During Cell Division"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"RNA Dependent Control of Chromatin Silencing"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Condensin I Directs Sister Chromatid Resolution Throughout Metaphase"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
6:00 pm - 6:20 pm
"Kinetochore
Remodeling During Meiosis Through the Regulation of Hec1"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Spo11, a 'Broken' Topoisomerase"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"The Causes of Chromosome Segregation
Errors in Mammalian Oocytes"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"The Role of Telomerase Dependent Attachments in Ensuring Meiotic Chromosome Motion"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"RNA-Associating Proteins Accumulated on the Chromosome During Homologous Chromosome Pairing in Meiosis"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Chromosome Cohesion and Condensation
9:00 am - 9:20 am
"Single-Nucleus Hi-C Reveals Unique Chromatin Reorganization During the Oocyte-to-Zygote Transition"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Structural and Mechanistic Insight into Cohesin Loading and Release"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Wapl, Pds5A and Pds5B Control Chromatin Compartments, TADs and Loops by Regulating Cohesin-DNA Interactions"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Fast Switches for a Slow Enzyme: Rescuing the Chromosome Condensation Machinery from the Chromatin Trap"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Role of Condensin in the Regulation of Gene Expression in Fission Yeast"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"The Smc5/6 Complex - Connecting DNA Supercoiling with Chromosome Segregation"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"The Roles of HAWK Subunits in Loading, Maintaining, and Releasing Cohesin from Chromosomes"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Structural Basis for Anchoring Eukaryotic Condensin to Chromosomes"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"New Integral Components of the E. coli and Salmonella SMC Complex"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Chromosome Replication and Repair
6:00 pm - 6:20 pm
"Archeal DNA Replication"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"A Mechanism of Replication Licensing in Bacteria: A Locus on Chr1 Licenses the Replication of Chr2 in Vibrio cholerae "
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
"The Abundance of Fob1p Modulates the Efficiency of rRFBs to Stall Replication Forks"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Regulation and Mechanism of Eukaryotic DNA Replication Initiation"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"A Compartmentalized Circuit Mediates Meiotic Crossover Control"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure