SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Dynamics of Transcription and Cell Cycles |
7:40 pm - 7:45 pm | Opening Remarks: Joe Takahashi |
7:45 pm - 8:10 pm | James McNally (National Cancer Institute, NIH) "Fast and slow cycling of transcriptional activators" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Sharad Ramanathan (Harvard University) "Dissecting timing variability in yeast meiosis" |
8:40 pm - 8:45 pm | Discussion |
8:45 pm - 9:10 pm | Ueli Schibler (University of Geneva) "Circadian transcriptional regulation" |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:30 pm | General Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:00 pm | Molecular Clock Mechanisms |
| Session Chair: Susan Golden (UCSD) |
9:00 am - 9:10 am | Chair’s Introduction |
9:10 am - 9:35 am | Takao Kondo (Nagoya University) "Dual control of the cyanobacterial circadian system" |
9:35 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Carl Johnson (Vanderbilt) "KaiABC oscillator: Core or periphery?" |
10:10 am - 10:35 am | Group Photo / Coffee Break |
10:35 am - 11:00 am | Jay Dunlap (Dartmouth University) "Proteomics and epigenetics of Neurospora clocks" |
11:00 am - 11:05 am | Discussion |
11:05 am - 11:30 am | Chuck Weitz (Harvard) "Proteomics of circadian clock protein complexes" |
11:30 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | General Discussion |
12:00 pm - 12:30 pm | HOT TOPICS I |
| Session Chair: Martha Merrow (University of Groningen) |
12:00 pm - 12:10 pm | Elzbeita Kowalska (University of Zurich)
"Characterization of NONO - a new player in the circadian clock work and senescence" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Frederic Gachon (CNRS UPR1142)
"Circadian clock-coordinated ultradian regulation of translation in mouse liver" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Human Clock Genetics |
| Session Chair: Michael Young (Rockefeller University) |
7:30 pm - 7:40 pm | Chair’s Introduction |
7:40 pm - 8:05 pm | Julianne Winkelmann (Technical University of Munich) "Genetics of restless legs syndrome" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Ying-Hui Fu (UCSF) "Genetics of circadian sleep disorders in humans" |
8:35 pm - 8:40 pm | Discussion |
8:40 pm - 9:05 pm | Thomas Bourgeron (Institut Pasteur) "Genetics of autistic spectrum disorders: links to circadian pathways" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:30 pm | General Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:00 pm | Clocks and Metabolism |
| Session Chair: Joe Bass (Northwestern University) |
9:00 am - 9:10 am | Chair’s Introduction |
9:10 am - 9:35 am | Ron Evans (Salk Institute) "Circadian regulation of metabolism" |
9:35 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Philippe Froguel (Imperial College) "Genetics of plasma glucose and type 2 diabetes risk: MTNR1B" |
10:05 am - 10:10 am | Discussion |
10:10 am - 10:35 am | Coffee Break |
10:35 am - 11:00 am | Benjamin Tu (UT Southwestern) "Significance of metabolic cycles" |
11:00 am - 11:05 am | Discussion |
11:05 am - 11:30 am | Z. Jeffrey Chen (University of Texas, Austin) "Growing around the clocks: Internal clocks promote growth vigor in hybrids and allopolyploids" |
11:30 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | General Discussion |
12:00 pm - 12:30 pm | HOT TOPICS II |
| Session Chair: Carla Green (University of Virginia) |
12:00 pm - 12:10 pm | Karen Gamble (Vanderbilt University)
"Shiftwork in nurses: Contribution of phenotypes and genotypes to adaptation" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Allan James (University of Glasgow)
"Alternative Splicing of Components of the Arabidopsis Circadian Clock" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Emerging roles for clock genes |
| Session Chair: Martha Merrow (University of Groningen) |
7:30 pm - 7:40 pm | Chair’s Introduction |
7:40 pm - 8:05 pm | Paul Frenette (Mt. Sinai) "Circadian trafficking of hematopoietic cells" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Bogi Anderson (UC Irvine) "Circadian clock genes and the hair cycle" |
8:35 pm - 8:40 pm | Discussion |
8:40 pm - 9:05 pm | Andrew C. Oates (Max Planck Institute, Dresden) "Synchrony dynamics of the segmental clock" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:30 pm | General Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:00 pm | Genetics of Drosophila Clocks |
| Session Chair: Amita Sehgal (University of Pennsylvania) |
9:00 am - 9:10 am | Chair’s Introduction |
9:10 am - 9:35 am | Trudy MacKay (North Carolina State University) "Systems Genetics of Sleep in the Drosophila Genetic Reference Panel" |
9:35 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Paul Taghert (Washington University, St. Louis) "Coordination of circadian oscillator neurons by neuropeptide signaling in Drosophila" |
10:05 am - 10:10 am | Discussion |
10:10 am - 10:35 am | Coffee Break |
10:35 am - 11:00 am | Ravi Allada (Northwestern University) "Sleep in Drosophila" |
11:00 am - 11:05 am | Discussion |
11:05 am - 11:30 am | Michael Nitabach (Yale University) "Neural regulation of Drosophila rhythms" |
11:30 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | General Discussion |
12:00 pm - 12:30 pm | HOT TOPICS III |
| Session Chair: Ignacio Provencio (University of Virginia) |
12:00 pm - 12:10 pm | Erin Fortier (McGill University, Canada)
"T cell response is controlled by the circadian clock" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Oscar Castanon-Cervantes (Morehouse School of Medicine)
"Fatal effects of an immune challenge following repeated phase shifts" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | Systems Biology of Circadian Clocks |
| Session Chair: Hiroki Ueda (RIKEN) |
7:30 pm - 7:40 pm | Chair’s Introduction |
7:40 pm - 8:05 pm | Steve Kay (UCSD) "On the significance of circadian programs" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | John Hogenesch (University of Pennsylvania) "Circadian network interactions" |
8:35 pm - 8:40 pm | Discussion |
8:40 pm - 9:05 pm | Achim Kramer (Charité, Berlin) "Genome-wide circadian RNAi screens" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:30 pm | General Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:00 pm | Mammalian Clocks and the SCN |
| Session Chair: Michael Menaker (University of Virginia) |
9:00 am - 9:10 am | Chair’s Introduction |
9:10 am - 9:35 am | Michael Hastings (MRC, Cambridge) "SCN: role of cAMP" |
9:35 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Samer Hattar (Johns Hopkins University) "Melanopsin cell pathways for entrainment" |
10:05 am - 10:10 am | Discussion |
10:10 am - 10:35 am | Coffee Break |
10:35 am - 11:00 am | Sato Honma (Hokkaido University) "Photic regulation of phase and tau; adaptive role of a kinase in the SCN" |
11:00 am - 11:05 am | Discussion |
11:05 am - 11:30 am | Erik Herzog (Washington University, St. Louis) "SCN oscillators: are they robust?" |
11:30 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | General Discussion |
12:00 pm - 12:30 pm | HOT TOPICS IV |
| Session Chair: Martha Gillette (University of Illinois) |
12:00 pm - 12:10 pm | Ute Abraham (Charité, Berlin)
"Odor modulates circadian behavior independent of the SCN" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Kazuhiro Yagita (Osaka University)
"Circadian Clock Generation in Mouse ES Cell Differentiation and Reprogramming" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Perspectives |
| Session Chair: Martin Zatz (NIMH/NIH JBR) |
7:30 pm - 7:40 pm | Chair’s Introduction |
7:40 pm - 8:05 pm | Michael Rosbash (Brandeis University) "On the Significance of Circadian Transcription" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Till Roenneberg (University of Munich) "Human chronotypes: phenotypes and genetics" |
8:35 pm - 8:40 pm | Discussion |
8:40 pm - 9:05 pm | Charalambos Kyriacou (University of Leicester) "Clocks in the real world" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:30 pm | General Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |