| SUNDAY |
| 4:00 pm - 8:00 pm | Arrival and Check-in (Check-in Desk Closed 6:00 pm - 7:45 pm) |
| 6:00 pm | Dinner |
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:40 pm - 9:30 pm | KEYNOTE LECTURES: NEW METHODS AND NEW INSIGHTS |
| 7:40 pm - 7:55 pm | Discussion Leaders: Martha Gilette (University of Illinois) and John Hogenesch (University of Pennsylvania) |
| 7:55 pm - 8:20 pm | Scott Sternson (HHMI Janelia Farm)
"A neural circuit for control of feeding" |
| 8:20 pm - 8:25 pm | Discussion |
| 8:25 pm - 8:50 pm | David Rand (University of Warwick)
"Theoretical approaches to understanding clock design principles" |
| 8:50 pm - 8:55 pm | Discussion |
| 8:55 pm - 9:20 pm | Kazuhiro Yagita (Kyoto Prefectural University of Medicine)
"Chronogenesis and cellular differentiation" |
| 9:20 pm - 9:25 pm | Discussion |
| 9:25 pm - 9:30 pm | General Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | THE CLOCK IN THE CELL |
| 9:00 am - 9:20 am | Discussion Leader: Luis Larondo (Universidad Católica de Chile) and Carl Johnson (Vanderbilt University) |
| 9:20 am - 9:45 am | Akilesh Reddy (University of Cambridge)
"Peroxiredoxins and metabolic oscillations in the clockwork" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:00 am | Hot Topic Talk: Jerome Menet (Brandeis University)
"Genome-wide transcriptional regulation by CLK:BMAL1 in mouse liver" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am | Coffee Break / Group Photo |
| 10:30 am - 10:55 am | Juergen Ripperger (University of Fribourg)
"Impact of dynamic histone H3.3 exchange on the mammalian circadian oscillator" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 11:25 am | Maria Mittag (University of Jena)
"The clockwork in the green biflagellate alga Chlamydomonas" |
| 11:25 am - 11:30 am | Discussion |
| 11:30 am - 11:55 am | Michael Brunner (University of Heidelberg)
"Generation of evening specific transcription in Neurospora" |
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:10 pm | Hot Topic Talk: Francois Rouyer (CNRS)
"A CULLIN-3 Ubiquitination Complex Controls TIMELESS Oscillations in the Drosophila Circadian Clock" |
| 12:10 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session I |
| 5:30 pm - 7:30 pm | THE CLOCK IN THE BRAIN |
| 5:30 pm - 5:45 pm | Discussion Leaders: Mary Harrington (Smith College) and TBA |
| 5:45 pm - 6:10 pm | Daniel Forger (University of Michigan)
"Multi-scale Complexity within the SCN" |
| 6:10 pm - 6:15 pm | Discussion |
| 6:15 pm - 6:40 pm | Stephan Michel (University of Leiden)
"Aging of the SCN neuronal network; implications for the regulation of sleep and behavioral activity" |
| 6:40 pm - 6:45 pm | Discussion |
| 6:45 pm - 7:10 pm | Michael Nitabach (Yale University)
"Allocation of Crepuscular Activity by a Homotypic Neuropeptide Relay" |
| 7:10 pm - 7:15 pm | Discussion |
| 7:15 pm - 7:30 pm | General Discussion |
| 8:00 pm | Dinner |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | THE RETINA AND THE CLOCK |
| 9:00 am - 9:20 am | Discussion Leaders: Samer Hatter (Johns Hopkins University) and Howard Cooper (Lyon) |
| 9:20 am - 9:45 am | Doug McMahon (Vanderbilt University)
"The Retinal Circadian Clock: Keeping the Eye On Time" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:00 am | Hot Topic Talk: Laura Lande-Diner (Harvard Medical School)
"TRAP150: A circadian interface between CLOCK-BMAL1 and the general transcription machinery" |
| 10:00 am | Coffee Break |
| 10:30 am - 10:55 am | Tim Brown (University of Manchester)
"Melanopsin ganglion cell contributions to sensory coding in central targets" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 11:25 am | Russell Foster (University of Oxford)
"Light input to the clock: Multiple signalling pathways" |
| 11:25 am - 11:30 am | Discussion |
| 11:30 am - 11:55 am | Charles Allen (Oregon State University)
"Signaling Mechanisms Mediating Suprachiasmatic Responses to Light Input" |
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:10 pm | Hot Topic Talk: Felix Naef (University of Lausanne)
"Fast stochastic switches underlie transcriptional bursting of circadian promoters in single mammalian cells" |
| 12:10 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session I |
| 5:30 pm - 7:30 pm | ENTRAINMENT OF THE CLOCK |
| 5:30 pm - 5:45 pm | Discussion Leader: Michael Rosbash (Brandeis University) and C. Kyriacou (Leicester University) |
| 5:45 pm - 6:10 pm | TBA |
| 6:10 pm - 6:15 pm | Discussion |
| 6:15 pm - 6:40 pm | Charlotte Helfrich-Foerster (University of Wuerzburg)
"Old mutants in new light" |
| 6:40 pm - 6:45 pm | Discussion |
| 6:45 pm - 7:10 pm | Ralf Stanewsky (Queen Mary University)
"Temperature entrainment of the clock in the fly" |
| 7:10 pm - 7:15 pm | Discussion |
| 7:15 pm - 7:30 pm | General Discussion |
| 8:00 pm | Dinner |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | THE EXPANDING CLOCK NETWORK IN THE CELL |
| 9:00 am - 9:20 am | Discussion Leaders: Jennifer Loros (Dartmouth Medical School) and Leslie Griffith (Brandeis University) |
| 9:20 am - 9:45 am | Deborah Bell-Pedersen (Texas A&M University)
"Clock regulation of conserved MAPK pathways" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:00 am | Hot Topic Talk: Fumika Hamada (Cincinnati Children's Hospital Medical Center)
"The circadian clock sets body temperature rhythm in Drosophila" |
| 10:00 am | Coffee Break |
| 10:30 am - 10:55 am | Carla Green (University of Texas Southwestern)
"Circadian post-transcriptional control of metabolism" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 11:25 am | Hitoshi Okamura (Kyoto University)
"Dysregulated, cell-specific ccg's lead to disease" |
| 11:25 am - 11:30 am | Discussion |
| 11:30 am - 11:55 am | Michael Rust (University of Chicago)
"Resetting the Cyanobacterial Clock with Nucleotides" |
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:10 pm | Hot Topic Talk: Patrick Emery (University of Massachusetts Medical School)
"GW182 modulates PDF-R signaling and circadian behavior in Drosophila" |
| 12:10 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session II |
| 5:30 pm - 7:30 pm | FITNESS AND THE CIRCADIAN CLOCK |
| 5:30 pm - 5:45 pm | Discussion Leaders: Serge Daan (University of Groningen) and Barbara Helm (Konstanz University and Max Planck Institute for Ornithology) |
| 5:45 pm - 6:10 pm | Seth Davis (Max Planck Institute for Plant Breeding Research)
"Stress signaling as an input and an output of the plant circadian clock" |
| 6:10 pm - 6:15 pm | Discussion |
| 6:15 pm - 6:40 pm | Jadwiga Giebultowicz (Oregon State University)
"The importance of circadian rhythms in preventing proteotoxicity during aging" |
| 6:40 pm - 6:45 pm | Discussion |
| 6:45 pm - 7:10 pm | Amita Sehgal (University of Pennsylvania)
"Circadian clocks and aging in Drosophila" |
| 7:10 pm - 7:15 pm | Discussion |
| 7:15 pm - 7:30 pm | General Discussion |
| 7:30 pm - 8:00 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
| 8:00 pm | Dinner |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | THE CLOCK IN HEALTH AND DISEASE: TRANSLATIONAL RESEARCH |
| 9:00 am - 9:15 am | Discussion Leaders: Till Roenneberg (University of Munich Medical School) and Maria Paz y Hidalgo (UFRGS, Brazil) |
| 9:15 am - 9:45 am | Debra Skene (University of Surrey)
"Lighting for older people: The challenges" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:00 am | Hot Topic Talk: Darwin Jeyaraj (Case Western Reserve University School of Medicine)
"Circadian rhythms govern cardiac repolarization and arrhythmogenesis" |
| 10:00 am | Coffee Break |
| 10:30 am - 10:55 am | Eva Schernhammer (Harvard University)
"Circadian-related genetic and environmental risk factors for cancer" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 11:25 am | Kenneth Wright (University of Colorado, Boulder)
"Circadian and sleep-wakefulness regulation of energy expenditure in humans" |
| 11:25 am - 11:30 am | Discussion |
| 11:30 am - 11:55 am | Marina Antoch (Roswell Park Cancer Insitute)
"A cross-talk between the circadian and NFkB pathways" |
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:10 pm | Hot Topic Talk: Frederic Gachon (University of Lausanne)
"The circadian clock coordinates ribosome biogenesis in mouse liver" |
| 12:10 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session II |
| 5:30 pm - 7:30 pm | INTEGRATION AND SYNTHESIS |
| 5:30 pm - 5:45 pm | Discussion Leaders: Gene Block (UCLA) and Rae Silver (Columbia University) |
| 5:45 pm - 6:10 pm | Joseph Takahashi (University of Texas Southwestern)
"Genetic analysis of circadian clocks in mammals" |
| 6:10 pm - 6:15 pm | Discussion |
| 6:15 pm - 6:40 pm | Andrew Millar (University of Edinburgh)
"Simple and complex clocks" |
| 6:40 pm - 6:45 pm | Discussion |
| 6:45 pm - 7:10 pm | William Schwartz (University of Massachusetts)
"Running in the night" |
| 7:10 pm - 7:15 pm | Discussion |
| 7:15 pm - 7:30 pm | General Discussion |
| 8:00 pm | Dinner |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
