Sunday |
4:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Systems and Concepts:
Rhythms, Oscillators and Clocks |
| Discussion Leader: Hiroki Ueda (RIKEN / The University of Tokyo, Japan) |
7:40 pm - 7:45 pm | Introduction by Discussion Leader |
7:45 pm - 8:10 pm | Michael Rosbash (Brandeis University, USA) "Relating Gene Expression Regulation in Identified Circadian Neurons to Functional Circuits and Behavior" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | James Locke (University of Cambridge, United Kingdom) "The Dynamic Coupling of Genetic Circuits" |
8:40 pm - 8:45 pm | Discussion |
8:45 pm - 9:10 pm | Matthew Bennett (Rice University, USA) "Using Synthetic Biology to Understand Biological Rhythms" |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:30 pm | General Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Clock Mechanisms:
Inputs and Outputs |
| Discussion Leader: Ravi Allada (Northwestern University, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Michael Brunner (University of Heidelberg, Germany) "Regulation of the Circadian Clock by cMYC" |
9:35 am - 9:40 am | Discussion |
9:40 am - 10:05 am | David Gatfield (University of Lausanne, Switzerland) "Ribosome Profiling Reveals the Rhythmic Liver Translatome and Circadian Clock Regulation
by Upstream Open Reading Frames" |
10:05 am - 10:10 am | Discussion |
10:10 am - 10:20 am | Ozgur Tataroglu (University of Massachusetts Medical School, USA) "A Conserved Mechanism for Circadian Thermal Responses in Flies and Mammals" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:55 am | Coffee Break |
10:55 am - 11:20 am | Joanna Chiu (University of California, Davis, USA) "Profiling Temporal Dynamics of Drosophila Clock Protein Posttranslational Modifications Using Quantitative Proteomics" |
11:20 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Carl Johnson (Vanderbilt University, USA) "Single-Molecule Studies of Circadian Synchronization" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:15 pm | General Discussion |
12:15 pm - 12:30 pm | Poster Previews |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | Clocks in the Brain:
Neuronal Control of Circadian Rhythms |
| Discussion Leader: Johanna Meijer (Leiden University, The Netherlands) |
6:00 pm - 6:05 pm | Introduction by Discussion Leader |
6:05 pm - 6:30 pm | Douglas McMahon (Vanderbilt University, USA) "SCN Timekeeping: Genes to Spikes and Back Again" |
6:30 pm - 6:35 pm | Discussion |
6:35 pm - 7:00 pm | Craig Montell (University of California, Santa Barbara, USA) "A New Circadian Photosensor in Flies" |
7:00 pm - 7:05 pm | Discussion |
7:05 pm - 7:15 pm | Olga Barca Mayo (Italian Institute of Technology, Italy) "Astrocytes Modulation of Neuronal Circadian Rhythms in Mammalian Brain" |
7:15 pm - 7:20 pm | Discussion |
7:20 pm - 7:45 pm | Joseph Takahashi (Howard Hughes Medical Institute / University of Texas Southwestern Medical Center, USA) "Integration of Suprachiasmatic Nucleus Neurons
and Behavior" |
7:45 pm - 7:50 pm | Discussion |
7:50 pm - 8:00 pm | General Discussion |
8:00 pm | Dinner |
9:30 pm | Poster Session (continued) |
Tuesday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Timing Is Everywhere:
Non-Circadian Rhythms |
| Discussion Leader: Charalambos Kyriacou (University of Leicester, United Kingdom) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Helge Grosshans (Friedrich Miescher Institute, Switzerland) "Timing C. elegans Development with Ultradian Gene Expression Oscillations" |
9:35 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Takashi Yoshimura (Nagoya University, Japan) "Mechanism of Seasonal Time Measurement in Vertebrates" |
10:05 am - 10:10 am | Discussion |
10:10 am - 10:20 am | Cristina Mazuski (Washington University in St. Louis, USA) "Identification of VIP Firing Patterns that Differentially Affect Circadian Rhythms" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:55 am | Coffee Break |
10:55 am - 11:20 am | Alexander Aulehla (European Molecular Biology Laboratory, Heidelberg, Germany) "Ultradian Signaling Oscillations During Embryonic Patterning and Scaling" |
11:20 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Florian Storch (McGill University, Canada) "Molecular Basis of Ultradian Rhythm Generation" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:15 pm | General Discussion |
12:15 pm - 12:30 pm | Poster Previews |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | The Clock in the
Cell: Transcriptional Regulation and Beyond |
| Discussion Leader: Yoshitaka Fukada (University of Tokyo, Japan) |
6:00 pm - 6:05 pm | Introduction by Discussion Leader |
6:05 pm - 6:30 pm | Takao Kondo (Nagoya University, Japan) "Design of Circadian Clock of Cyanobacteria by Dual ATPase Domains of KaiC" |
6:30 pm - 6:35 pm | Discussion |
6:35 pm - 7:00 pm | Charles Weitz (Harvard Medical School, USA) "Toward Understanding the PERIOD Complex as a Macromolecular Machine" |
7:00 pm - 7:05 pm | Discussion |
7:05 pm - 7:15 pm | Marrit Putker (Medical Research Council Laboratory of Molecular Biology, United Kingdom) "Some Rhythm, No Cry - Characterisation of Circadian Timekeeping in Cry1/2-Deficient Mammalian Fibroblasts" |
7:15 pm - 7:20 pm | Discussion |
7:20 pm - 7:45 pm | Jonathan Lipton (Boston Children's Hospital / Harvard Medical School, USA) "Mechanisms of Circadian Translation" |
7:45 pm - 7:50 pm | Discussion |
7:50 pm - 8:00 pm | General Discussion |
8:00 pm | Dinner |
9:30 pm | Poster Session (continued) |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Timely
Defense: Circadian Control of Immune Functions |
| Discussion Leader: Marina Antoch (Roswell Park Cancer Institute, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Janet Braam (Rice University, USA) "Timing Plant Defense: Attention Herbivores!" |
9:35 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Mimi Shirasu-Hiza (Columbia University Medical School, USA) "Phagocytic Defense Mechanisms in Drosophila" |
10:05 am - 10:10 am | Discussion |
10:10 am - 10:20 am | Marie Pariollaud (University of Manchester, United Kingdom) "A Novel Mechanism Links Inflammation to the Clock Through REV-ERBa Protein Stability" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:55 am | Coffee Break |
10:55 am - 11:20 am | Christoph Scheiermann (Ludwig Maximilians University Munich, Germany) "Circadian Rhythms in Immune Cell Trafficking" |
11:20 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Eran Elinav (Weizmann Institute of Science, Israel) "Microbiome Time" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:15 pm | General Discussion |
12:15 pm - 12:30 pm | Poster Previews |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | Growth, Cancer and
the Clock |
| Discussion Leader: Steven Brown (University of Zürich, Switzerland) |
6:00 pm - 6:05 pm | Introduction by Discussion Leader |
6:05 pm - 6:30 pm | Carla Finkielstein (Virginia Polytechnic Institute and State University, USA) "Clock Proteins: New Players in DNA-Damage Signaling" |
6:30 pm - 6:35 pm | Discussion |
6:35 pm - 7:00 pm | Katja Lamia (The Scripps Research Institute, USA) "Cry1 and Cry2 Integrate DNA Damage with Circadian Time" |
7:00 pm - 7:05 pm | Discussion |
7:05 pm - 7:15 pm | Chris Hong (University of Cincinnati, USA) "Circadian Clock-Gated Synchronized Cell Division Cycles in 3D Enteroids from Mouse Small Intestine" |
7:15 pm - 7:20 pm | Discussion |
7:20 pm - 7:45 pm | Stacey Harmer (University of California, Davis, USA) "Rhythms and Greens: Clock Regulation of Plant Behavior" |
7:45 pm - 7:50 pm | Discussion |
7:50 pm - 8:00 pm | General Discussion |
8:00 pm | Dinner |
9:30 pm | Poster Session (continued) |
Thursday |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
9:00 am - 12:30 pm | Entrainment and Sleep |
| Discussion Leader: Martha Merrow (University of Munich, Germany) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Amita Sehgal (University of Pennsylvania, USA) "Molecules Underlying Sleep in Drosophila" |
9:35 am - 9:40 am | Discussion |
9:40 am - 10:05 am | David Prober (California Institute of Technology, USA) "Circadian Regulation of Sleep in Zebrafish" |
10:05 am - 10:10 am | Discussion |
10:10 am - 10:20 am | Todd Holmes (University of California at Irvine School of Medicine, USA) "Longitudinal Imaging of Drosophila Circadian Neural Circuit Responses to Light Entrainment Cues" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:55 am | Coffee Break |
10:55 am - 11:20 am | Samer Hattar (Johns Hopkins University, USA) "Irregular Light Exposure as a Risk Factor for Neurological Disorders" |
11:20 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Till Roenneberg (University of Munich, Germany) "The Human Sleep Project: Scope and First Results" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:15 pm | General Discussion |
12:15 pm - 12:30 pm | Poster Previews |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | Metabolism and Aging:
The Role of the Clock |
| Discussion Leader: Fernanda Ceriani (Leloir Institute Foundation, Argentina) |
6:00 pm - 6:05 pm | Introduction by Discussion Leader |
6:05 pm - 6:30 pm | Carla Green (University of Texas Southwestern Medical Center, USA) "Circadian Post-Transcriptional Control of Metabolism" |
6:30 pm - 6:35 pm | Discussion |
6:35 pm - 7:00 pm | Roman Kondratov (Cleveland State University, USA) "Delay of Aging by Calorie Restriction, Circadian Approach" |
7:00 pm - 7:05 pm | Discussion |
7:05 pm - 7:15 pm | Mathias Foo (Asia Pacific Center for Theoretical Physics, South Korea) "Unraveling the Core Genetic Circuitry of the Plant Circadian System Through Computational Model" |
7:15 pm - 7:20 pm | Discussion |
7:20 pm - 7:45 pm | Ueli Schibler (University of Geneva, Switzerland) "The Systemic Control of Circadian Gene Expression by Blood-Borne and Temperature-Dependent Signals" |
7:45 pm - 7:50 pm | Discussion |
7:50 pm - 8:00 pm | General Discussion |
8:00 pm | Dinner |
9:30 pm | Poster Session (continued) |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |