Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Advances in Sleep and Circadian Research
7:40 pm - 7:55 pm
Introduction by Discussion Leader
7:55 pm - 8:15 pm
"Multimodal Non-Photic Inputs to the Suprachiasmatic Nucleus in Mice"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
"How to Eat More, Lose Fat, and Live Longer"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"Time Matters: Circadian Control of Metabolism"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Novel Clock Neuron Subtypes Regulate Temporal Aspects of Sleep"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
"Circadian and Sleep Disruption and the Microbiome"
9:35 am - 9:40 am
Discussion
9:40 am - 10:00 am
"How The Sun and The Moon Time Our Sleep"
10:00 am - 10:05 am
Discussion
10:05 am - 10:25 am
"The Electrophysiological and Transcriptomic Responses to an Alkaloid Sleep Inducer are Shaped by Clock Time"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Disordered Proteoforms in the Negative Arm of the Clock Regulate Interactomes to Control Circadian Temperature Responses"
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"A new Ultradian Rhythm in Mammalian Cell Dry Mass Observed by Holography"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"TLWD Scaffold Proteins Sustain Sircadian Function in Arabidopsis"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Discoveries from Across the Phylogenetic Tree
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:05 pm
"Circadian Clocks in the Non-Photosynthetic Bacteria"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Moving on from Lux to Facilitate Cross-Species Comparisons of Photosensitivity"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Photoperiodic Measurement Mechanisms in Plants"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"The Evolution of Sleep Loss in Cavefish"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Circadian Photoentrainment
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
"Genetic Underpinnings of ipRGC Diversity"
9:35 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Towards Understanding Molecular Bases of Infradian Rhythms"
10:00 am - 10:05 am
Discussion
10:05 am - 10:25 am
"A novel Role for Melanopsin Signaling in Diurnal Photoreceptor Phagocytosis"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Watching the Gears of the Circadian Clock Reset in Real Time"
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
"Timing Physiology and Behavior by the Moon"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"A Genetic Model for Understanding the Timekeeping Mechanism During Chronic Social Isolation"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Do Bacteria Care About the Seasons? Evidence of Photoperiodic Time-Measurement in Cyanobacteria"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Role of Circadian Clocks in Microbes
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:05 pm
"Punctual Parasites: Why Rhythmic Replication is Advantageous for Malaria Parasites"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Gut Microbially Produced Bile Acid Metabolite Lengthens Circadian Period in Host Intestinal Cells"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Circadian Regulation of Viruses"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Circadian Anti-Tumor Immune Responses"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
"The Cell Biology of the Circadian Clock in Mammals"
9:35 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Remodeling of Circadian Pacemaker Projections, Not Merely a Neuronal Tale"
10:00 am - 10:05 am
Discussion
10:05 am - 10:25 am
"Cooperativity and Competition in CLOCK:BMAL1 Regulation"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Nutrient-Dependent Regulation of Biological Rhythms"
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
"BMAL1-HIF2a Heterodimers Contribute to Renal Cancer Growth"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Divided and Conquered: Fragmenting the Day-Night Cycle Negatively Impacts Circadian Rhythms, Mood, and Development in Mice"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"A Non-Human Primate Model to Study Circannual Rhythm"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:05 pm
"Development of the Circadian Rhythm"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Dissecting the Role of the Circadian Clock in Cancer"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"A Novel Role for Endothelin B Receptors in High Salt Diet-Induced Circadian Disruption"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Human Period3 Variants Lead to Winter Depression-Like Phenotypes Via Glucocorticoid and Serotonin"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Clock Circuits and Connectivity
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
"Sex Differences in Central Clock Circuits Controlling Daily Rhythms"
9:35 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Sex Differences in the Drosophila Circadian Clock Neuron Network"
10:00 am - 10:05 am
Discussion
10:05 am - 10:25 am
"Ins and Outs of Circadian Time"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"The Glymphatic System as a Target for Circadian Entrainment?"
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
"Circadian Sleep/Wake Dysregulation in Neurodevelopmental Disorders"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Defining the Role of TGF-beta Signaling for Intercellular Coupling and Circadian Entrainment"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Differential Temperature Sensitivity of Protein Synthesis Drives the Mammalian Nocturnal-Diurnal Switch"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Role of Clocks in Physiology and Metabolism
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:05 pm
"Circadian Control of Floret Development in Sunflower"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Time Restricted Feeding in Mammals Including Non-Human Primates"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Melatonin Receptor 1b Variation, Chronotype and Glucose Metabolism"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Circadian Regulation of Metabolic Risk in Mice and Women"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure